scholarly journals Alcohol Drinking Pattern and Risk of Head and Neck Cancer: A Nationwide Cohort Study

2021 ◽  
Vol 18 (21) ◽  
pp. 11204
Author(s):  
Hye Yeon Koo ◽  
Kyungdo Han ◽  
Dong Wook Shin ◽  
Jung Eun Yoo ◽  
Mi Hee Cho ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cohort Study ◽  
Head And Neck Cancer ◽  
Alcohol Consumption ◽  
Oral Cavity ◽  
Head And Neck ◽  
Neck Cancer ◽  
Daily Amount ◽  
Average Alcohol ◽  
Drinking Frequency

Alcohol consumption is a major risk factor for head and neck cancer (HNC), yet little data exist examining drinking patterns and HNC risk. In this population-based, retrospective cohort study, 11,737,467 subjects were recruited from the Korean National Health Insurance Service database. The risks of overall HNC and HNC subtypes according to average alcohol consumption, drinking frequency, and daily amount were examined using Cox proportional hazard models. Over the median follow-up of 6.4 years, 15,832 HNC cases were identified. HNC risk linearly increased with drinking frequency (p-trend < 0.01; adjusted hazard ratio [aHR] 1.55, 95% confidence interval [CI] 1.45–1.67 in subjects who drank 7 days/week). HNC risk also increased according to daily amount of alcohol consumption (p-trend < 0.01), but plateaued from 5–7 units/occasion (aHR 1.25, 95% CI 1.19–1.31) to >14 units/occasion (aHR 1.26, 95% CI 1.13–1.40). When stratified by average alcohol consumption, drinking frequency, but not daily amount, showed a linear relationship with HNC risk in moderate and heavy drinkers. When comparing the HNC subtypes, similar tendencies were observed in cancers of the oral cavity, pharynx, and larynx, but not in the salivary gland. In conclusion, drinking frequency is a stronger risk factor for HNC, especially for cancer of the oral cavity, pharynx, and larynx, than the daily amount of alcohol consumption.

scholarly journals Alcohol Consumption as a Major Risk Factor in the Development of Early Esophageal Cancer in Patients with Head and Neck Cancer.

2001 ◽  
Vol 40 (8) ◽  
pp. 692-696 ◽  
Author(s):  
Hiroki TANABE ◽  
Kinichi YOKOTA ◽  
Naomi SHIBATA ◽  
Tomonobu SATOH ◽  
Jiro WATARI ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Risk Factor ◽  
Head And Neck Cancer ◽  
Alcohol Consumption ◽  
Head And Neck ◽  
Neck Cancer ◽  
Major Risk Factor ◽  
Early Esophageal Cancer

Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention

2019 ◽  
Vol 73 (6) ◽  
pp. 24-31
Author(s):  
Andrzej Kowalski ◽  
Jurek Olszewski ◽  
Hanna Zielińska-Bliźniewska
Keyword(s):  
Risk Factors ◽  
Head And Neck Cancer ◽  
Alcohol Consumption ◽  
Oral Cavity ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Sex ◽  
Burning Pain ◽  
Family Medical History ◽  
Hygiene Measures

Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.

Patterns of Care in Elderly Head-and-Neck Cancer Radiation Oncology Patients: A Single-Center Cohort Study

2011 ◽  
Vol 79 (1) ◽  
pp. 46-51 ◽  
Author(s):  
Shao Hui Huang ◽  
Brian O'Sullivan ◽  
John Waldron ◽  
Gina Lockwood ◽  
Andrew Bayley ◽  
...  
Keyword(s):  
Cohort Study ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Radiation Oncology ◽  
Patterns Of Care ◽  
Single Center ◽  
Oncology Patients

Low‐dose aspirin use and mortality risk in patients with head and neck cancer – a nationwide cohort study of 10,770 patients

2021 ◽  
Author(s):  
Cecilie D. Cour ◽  
Christian Buchwald ◽  
Christian Dehlendorff ◽  
Martin Garset‐Zamani ◽  
Christian Grønhøj ◽  
...  
Keyword(s):  
Cohort Study ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Mortality Risk ◽  
Low Dose ◽  
Dose Aspirin ◽  
Low Dose Aspirin

Days alive and out of hospital following transoral robotic surgery: Cohort study of 262 patients with head and neck cancer

Head & Neck ◽  
2021 ◽  
Author(s):  
Mikkel H. H. Larsen ◽  
Susanne I. Scott ◽  
Hani I. Channir ◽  
Anne K. Ø. Madsen ◽  
Birgitte W. Charabi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Head And Neck Cancer ◽  
Robotic Surgery ◽  
Head And Neck ◽  
Neck Cancer ◽  
Transoral Robotic Surgery

DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage

2007 ◽  
Vol 121 (8) ◽  
pp. 1724-1728 ◽  
Author(s):  
Ian M. Smith ◽  
Wojciech K. Mydlarz ◽  
Suhail K. Mithani ◽  
Joseph A. Califano
Keyword(s):  
Head And Neck Cancer ◽  
Alcohol Consumption ◽  
Head And Neck ◽  
Neck Cancer ◽  
Squamous Cell ◽  
Global Hypomethylation

The association with xerostomia from sialadenitis and the jaw osteonecrosis in head and neck cancer population: a nationwide cohort study

2018 ◽  
Vol 23 (2) ◽  
pp. 585-593 ◽  
Author(s):  
Yi-Fang Huang ◽  
Chih-Hsin Muo ◽  
Chun-Hao Tsai ◽  
Shih-Ping Liu ◽  
Chung-Ta Chang
Keyword(s):  
Cohort Study ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Jaw Osteonecrosis

Quality Indicators: Measurement and Predictors in Head and Neck Cancer Free Flap Patients

2018 ◽  
Vol 158 (2) ◽  
pp. 265-272 ◽  
Author(s):  
Antoine Eskander ◽  
Stephen Y. Kang ◽  
Benjamin Tweel ◽  
Jigar Sitapara ◽  
Matthew Old ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Length Of Stay ◽  
Oral Cavity ◽  
Head And Neck ◽  
Neck Cancer ◽  
Free Flap ◽  
Preoperative Assessment ◽  
Assessment Clinic ◽  
Primary Radiotherapy ◽  
The Impact

Objective To determine the predictors of length of stay (LOS), readmission within 30 days, and unplanned return to the operating room (OR) within 30 days in head and neck free flap patients. Study Design Case series with chart review. Setting Tertiary academic cancer hospital. Subjects and Methods All head and neck free flap patients at The Ohio State University (OSU, 2006-2012) were assessed. Multivariable logistic regression to assess the impact of patient factors, flap and wound factors, and intraoperative factors on the aforementioned quality metric outcomes. Results In total, 515 patients were identified, of whom 66% had oral cavity cancers, 33% had recurrent tumors, and 28% underwent primary radiotherapy. Of the patients, 31.5% had a LOS greater than 9 days, predicted by longer operative time, oral cavity and pharyngeal tumor sites, blood transfusion, diabetes mellitus, and any complication. A total of 12.6% of patients were readmitted within 30 days predicted by absent OSU preoperative assessment clinic attendance and any complication, and 14.8% of patients had an unplanned OR return predicted by advanced age. Conclusions When assessing quality metrics, adjustment for the complexity involved in managing patients with head and neck cancer with a high comorbidity index, clean contaminated wounds, and a high degree of primary radiotherapy is important. Patients seen in a preoperative assessment clinic had a lower risk of readmission postoperatively, and this should be recommended for all head and neck free flap patients. Quality improvement projects should focus on predictors and prevention of complications as this was the number one predictor of both increased length of stay and readmission.

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