scholarly journals Oxidised Low Density Lipoprotein (LDL) Modification with Statin Therapy is Associated with Reduction in Carotid Stenosis

Author(s):  
Elias Skopelitis ◽  
Dimitrios Levisianou ◽  
Helen Lydataki ◽  
Sofoklis Kougialis

2010 ◽  
Vol 11 (2) ◽  
pp. 115-116
Author(s):  
S. Kougialis ◽  
D. Levisianou ◽  
E. Skopelitis ◽  
S. Nikolaou ◽  
A. Kroustalis ◽  
...  


10.5772/25833 ◽  
2012 ◽  
Author(s):  
Elias Skopelitis ◽  
Dimitrios Levisianou ◽  
Theodore Gialernios ◽  
Sofoklis Kougialis


2021 ◽  
Vol 10 (7) ◽  
pp. 1480
Author(s):  
Keishi Ichikawa ◽  
Toru Miyoshi ◽  
Kazuhiro Osawa ◽  
Takashi Miki ◽  
Hiroshi Ito

Objective: To evaluate the association of serum malondialdehyde low-density lipoprotein (MDA-LDL), an oxidatively modified LDL, with the prevalence of high-risk plaques (HRP) determined with coronary computed tomography angiography (CTA) in statin-treated patients. Methods: This study was a single-center retrospective cohort comprising 268 patients (mean age 67 years, 58% men) with statin therapy and who underwent coronary CTA for suspected stable coronary artery disease. Patients were classified into two groups according to median MDA-LDL level or median LDL-C level. Coronary CTA-verified HRP was defined when two or more characteristics, including positive remodeling, low-density plaques, and spotty calcification, were present. Results: Patients with HRP had higher MDA-LDL (p = 0.011), but not LDL-C (p = 0.867) than those without HRP. High MDA-LDL was independently associated with HRP (odds ratio 1.883, 95% confidential interval 1.082–3.279) after adjustment for traditional risk factors. Regarding incremental value of MDA-LDL for predicting CTA-verified HRP, addition of serum MDA-LDL levels to the baseline model significantly increased global chi-square score from 26.1 to 32.8 (p = 0.010). Conclusions: A high serum MDA-LDL level is an independent predictor of CTA-verified HRP, which can lead to cardiovascular events in statin-treated patients.



1995 ◽  
Vol 24 (4) ◽  
pp. 209-211 ◽  
Author(s):  
A. Savolainen ◽  
R. von Essen ◽  
J. Leikola ◽  
G. Alfthan ◽  
O. Vaarala ◽  
...  


2017 ◽  
Vol 20 (C) ◽  
pp. 109
Author(s):  
Nikolaos Ioakeimidis ◽  
Charalambos Vlachopoulos ◽  
Athanasios Angelis ◽  
Dimitrios Terentes- Printzios ◽  
Christos Georgakopoulos ◽  
...  


2011 ◽  
Vol 18 (7) ◽  
pp. 568-573 ◽  
Author(s):  
Jong-Hwan Park ◽  
Masashi Miyashita ◽  
Masaki Takahashi ◽  
Kazuhiro Harada ◽  
Kanae Takaizumi ◽  
...  


2015 ◽  
Vol 9 (3) ◽  
pp. 298-300 ◽  
Author(s):  
Antonio Laguna-Camacho ◽  
Arely S. Alonso-Barreto ◽  
Hugo Mendieta-Zerón




Sign in / Sign up

Export Citation Format

Share Document