scholarly journals Uterine Embolization as a New Treatment Option in Adenomyosis Uteri

2021 ◽  
Author(s):  
Panagiotis Tsikouras ◽  
Fotini Gaitatzi ◽  
Stefani Filiou ◽  
Spyridon Michalopoulos ◽  
Aggeliki Gerede ◽  
...  
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Clinical Symptoms ◽  
Treatment Options ◽  
Smooth Muscles ◽  
Premenopausal Women ◽  
Uterine Wall ◽  
Invasive Treatment ◽  
New Treatment ◽  
Case Basis

Adenomyosis is characterized by the development of endometrial ectopic glands and tissue in the myometrium layer in depth greater than 2.5 mm from the endometrial surface of the separative area by -myomas well as by hypertrophy and hyperplasia of the smooth muscles of the myometrium. This is filtration, not mere displacement, of the myometrium, from the endometrium. Clinical symptoms include dysmenorrhea and menorrhagia. It is diffuse (adenomyosis) or focal (adenomyoma), asymmetrically affects the uterine wall of premenopausal women (usually the posterior) and often coexists with myomas. The pathogenesis of adenomyosis remains unknown. The treatment options are: drug therapy, invasive treatment of fibroids: myomectomy (open—intra-abdominal, laparoscopic, hysteroscopic), hysterectomy, myolysis—cryocatalysis, microwave or radiofrequency thermal catalysis (RF-ablation), ultrasound focus catalysis (FUS), laser photocatalysis and percutaneous selective uterine artery embolization (UAE). Embolization remains an alternative and not a substitute of hysterectomy. The medical indication is made on a case-by-case basis, depending on age, desire for pregnancy and the clinical symptoms of adenomyosis.

scholarly journals Uterine Artery Embolization as Nonsurgical Treatment of Uterine Myomas

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Strinic Tomislav ◽  
Maskovic Josip ◽  
Cambi Sapunar Liana ◽  
Vulic Marko ◽  
Jukic Marko ◽  
...  
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Clinical Symptoms ◽  
Uterine Fibroids ◽  
Normal Activity ◽  
Uneventful Recovery ◽  
Artery Embolization ◽  
Invasive Treatment ◽  
Variable Intensity

The purpose of this study was to evaluate safety, efficacy or complications of uterine artery embolization (UAE). Patients with symptomatic uterine fibroids (n=157) were treated by selective bilateral UAE using 350–500 μm sized polyvinyl alcohol particles. Bilateral UAE was successful in 152 (96.8%) cases. Baseline measures of clinical symptoms and MRI taken before the procedure were compared to those taken 3, 6, and 12 months after embolotherapy. Also, complications and outcomes were analyzed after procedure. All patients had an uneventful recovery and were able to return to normal activity within two weeks of embolization. After the procedure, most patients experienced crampy pelvic pain, of variable intensity, which was well managed with the standard analgesia protocol. Five (3%) of participants had persisting amenorrhea after procedure. None reported any new gynecologic or medical problem during the follow-up period. There were no deaths and no major permanent injuries. Reductions in mean uterine volume were 61% (P<0.01) and in dominant fibroid volume 66% (P≤0.01). The follow-up showed significant improvement of bleeding. In conclusion, uterine artery embolization is a successful, minimal invasive treatment of uterine fibroids that preserves the uterus, had minimal complications, and requires short hospitalization and recovery.

Acute lymphoblastic leukaemia

2020 ◽  
pp. 5269-5280
Author(s):  
H. Josef Vormoor ◽  
Tobias F. Menne ◽  
Anthony V. Moorman
Keyword(s):  
Acute Lymphoblastic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Kinase Inhibitors ◽  
Clinical Symptoms ◽  
Bone Marrow Failure ◽  
Treatment Options ◽  
Intrathecal Methotrexate ◽  
New Treatment ◽  
B Lineage ◽  
Relapsed Disease

Acute lymphoblastic leukaemia (ALL) is a malignant proliferation of lymphoid blasts, most commonly of B-lineage origin. The clinical symptoms and signs are either a consequence of bone marrow failure (infections, bruising, petechiae, pallor, and tiredness) or a consequence of the uncontrolled proliferation of the blasts (lymphadenopathy, hepatosplenomegaly, and cranial nerve palsies). Its peak incidence is in young children but ALL occurs at all ages. More than 80% of all affected children are cured with modern chemotherapy, but unfortunately the outcome of adults is much worse despite some improvements led by the introduction of paediatric-inspired protocols and tyrosine kinase inhibitors in BCR-ABL1-positive ALL. Standard chemotherapy for ALL consists of several months of intensive multidrug induction, consolidation and intensification chemotherapy (including steroids, vincristine, asparaginase and anthracyclines), intrathecal methotrexate to target blasts in the central nervous system, and low-intensity maintenance therapy (with oral 6-mercaptopurine and methotrexate) for up to 3 years. Treatment is stratified according to the response and other prognostic biomarkers (including genetics). Allogeneic haematopoietic stem cell transplantation is used predominantly in the relapse setting for children but in frontline therapy for adult patients to consolidate chemotherapy. Novel targeted small molecules and, in particular, immunotherapy are promising to offer new treatment options for patients with high-risk or relapsed disease.

A uterine wall defect after uterine artery embolization for symptomatic myomas

2002 ◽  
Vol 77 (1) ◽  
pp. 176-178 ◽  
Author(s):  
Pier Andrea De Iaco ◽  
Giuseppe Muzzupapa ◽  
Rita Golfieri ◽  
Michela Ceccarini ◽  
Brunilde Roset ◽  
...  
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Uterine Wall ◽  
Artery Embolization ◽  
Wall Defect

Uterine Artery Embolization is Advanced, Minimally Invasive Treatment for Fibroids with Intervention Procedure: A Case Report

2014 ◽  
Vol 1 (1) ◽  
pp. 47
Author(s):  
Chandrashekhar M. Gattani ◽  
Tejas P. Sadavarte ◽  
Shripad S. Kamble
Keyword(s):  
Minimally Invasive ◽  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Posterior Wall ◽  
Contrast Study ◽  
Lower Abdomen ◽  
Artery Embolization ◽  
Invasive Treatment ◽  
Intervention Procedure

<p>Uterine Artery Embolization (UAE) has become most effective and minimally invasive alternative treatment over the past many years, especially for women with symptomatic fibroids for whom conservation of uterus is important. Here we are reporting a case of an eighteen year old, unmarried female who presented with pain in lower abdomen and pelvis, menorrhagia and she also noticed gradually increasing lump in pelvis and lower abdomen.</p><p>After clinical examination, patient was referred for radiological investigations, initially ultrasonography was performed which revealed, a large sized posterior wall uterine fibroid measuring approx. 19 x 10 x 18 cm and it was further confirmed on MRI with contrast study. UAE was carried out in order to relieve the symptoms, reduce the size of fibroid and at the same time preserve the uterus. The procedure was uneventful after follow-up for 3 months, there was partial regression in the size of fibroid.</p>

Effects of uterine artery embolization on life quality in premenopausal women

2016 ◽  
Vol 76 (10) ◽  
Author(s):  
S Gyroglou ◽  
A Liberis ◽  
B Manav ◽  
P Naoumis ◽  
C Bouschanetsis ◽  
...  
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Life Quality ◽  
Premenopausal Women ◽  
Artery Embolization

Uterine Fibroids

2021 ◽  
Author(s):  
Kari Plewniak ◽  
Hye-Chun Hur
Keyword(s):  
Key Words ◽  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Treatment Options ◽  
Uterine Fibroids ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Hormonal Status ◽  
Artery Embolization ◽  
Medical Comorbidities

Uterine fibroids may be present in up to 80% of women and are the most common benign indication for hysterectomy. Symptoms related to fibroids can vary tremendously and depend on the number, size, and location of fibroids, as well as the patient’s hormonal status. Several different treatment options are available for fibroids. A variety of factors, such as a patient’s symptoms, age, reproductive goals, and medical comorbidities, help determine which treatment is best for each patient.  This review contains 11 figures, 4 tables and 55 references Key Words: abnormal uterine bleeding, fibroids, FIGO fibroid classification, hysterectomy, leiomyoma, myomectomy, uterine artery embolization

scholarly journals Hospital trends of admissions and procedures for acute leg ischaemia in England, 2000–2011

2015 ◽  
Vol 97 (1) ◽  
pp. 59-62 ◽  
Author(s):  
RS von Allmen ◽  
A Anjum ◽  
JT Powell ◽  
JJ Earnshaw
Keyword(s):  
Hospital Admissions ◽  
Treatment Options ◽  
Treatment Modalities ◽  
Mortality Data ◽  
Age Group ◽  
Hospital Data ◽  
Invasive Treatment ◽  
Common Procedure ◽  
Endovascular Interventions ◽  
New Treatment

IntroductionAcute leg ischaemia (ALI) is a common vascular emergency for which new minimally invasive treatment options were introduced in the 1990s. The aim of this study was to determine recent hospital trends for ALI in England and to assess whether the introduction of the new treatment modalities had affected management.MethodsRoutine hospital data covering ALI were provided by Hospital Episode Statistics for the years 2000 to 2011 and mortality data were obtained from the Office for National Statistics. All data were age standardised, reported per 100,000 of the population, and stratified by age band (60–74 years and ≥75 years) and sex.ResultsHospital admissions have risen significantly from 60.3 to 94.3 per 100,000 of the population, with an average annual increase of 6.2% since 2003 (p<0.001). The rise was greater in the older age group (from 79.9 to 134.4 vs 49.3 to 73.0) and yet procedures for ALI have shown a significant decrease since 2000 from 14.3 to 12.4 per 100,000 (p=0.013), independent of age and sex. Open embolectomy of the femoral artery remains the most common procedure and the proportion of endovascular interventions showed only a small increase. Only a few deaths were attributed to ALI (range: 95–150 deaths per year).ConclusionsHospital workload for ALI has increased, particularly since 2003, but this trend does not appear to have translated into increased endovascular or surgical activity.

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