scholarly journals The Role of Green Tea Polyphenols in the Protection from Hexavalent Chromium-Induced Genotoxic Damage

Polyphenols ◽  
2018 ◽  
Author(s):  
María del Carmen García-Rodríguez ◽  
Mario Altamirano-Lozano ◽  
Alejandro Gordillo-García
Keyword(s):  
Green Tea ◽  
Hexavalent Chromium ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Genotoxic Damage

scholarly journals Antigenotoxic and Apoptotic Activity of Green Tea Polyphenol Extracts on Hexavalent Chromium-Induced DNA Damage in Peripheral Blood of CD-1 Mice: Analysis with Differential Acridine Orange/Ethidium Bromide Staining

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
María del Carmen García-Rodríguez ◽  
Megumi Monserrat Carvente-Juárez ◽  
Mario Agustín Altamirano-Lozano
Keyword(s):  
Acridine Orange ◽  
Green Tea ◽  
Hexavalent Chromium ◽  
Ethidium Bromide ◽  
Peripheral Blood ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Genotoxic Damage ◽  
Green Tea Polyphenol ◽  
Apoptotic Activity

This study was conducted to investigate the modulating effects of green tea polyphenols on genotoxic damage and apoptotic activity induced by hexavalent chromium [Cr (VI)] in CD-1 mice. Animals were divided into the following groups: (i) injected with vehicle; (ii) treated with green tea polyphenols (30 mg/kg) via gavage; (iii) injected with CrO3(20 mg/kg) intraperitoneally; (iv) treated with green tea polyphenols in addition to CrO3. Genotoxic damage was evaluated by examining micronucleated polychromatic erythrocytes (MN-PCEs) obtained from peripheral blood at 0, 24, 48, and 72 h after treatment. Induction of apoptosis and cell viability were assessed by differential acridine orange/ethidium bromide (AO/EB) staining. Treatment of green tea polyphenols led to no significant changes in the MN-PCEs. However, CrO3treatment significantly increased MN-PCEs at 24 and 48 h after injection. Green tea polyphenols treatment prior to CrO3injection led to a decrease in MN-PCEs compared to the group treated with CrO3only. The average of apoptotic cells was increased at 48 h after treatment compared to control mice, suggesting that apoptosis could contribute to eliminate the DNA damaged cells induced by Cr (VI). Our findings support the proposed protective effects of green tea polyphenols against the genotoxic damage induced by Cr (VI).

scholarly journals Therapeutic Role of Green Tea Polyphenols in Improving Fertility: A Review

Nutrients ◽  
2018 ◽  
Vol 10 (7) ◽  
pp. 834 ◽  
Author(s):  
Sajid Rahman ◽  
Yingying Huang ◽  
Lei Zhu ◽  
Shibin Feng ◽  
Ibrar Khan ◽  
...  
Keyword(s):  
Green Tea ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Therapeutic Role

scholarly journals Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: Possible role of reactive oxygen species

2010 ◽  
Vol 88 (16) ◽  
pp. 3644-3655 ◽  
Author(s):  
Usha Gundimeda ◽  
Thomas H. McNeill ◽  
Jason E. Schiffman ◽  
David R. Hinton ◽  
Rayudu Gopalakrishna
Keyword(s):  
Reactive Oxygen Species ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Green Tea ◽  
Reactive Oxygen ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Oxygen Species ◽  
Nerve Growth

Role of green tea polyphenols in the inhibition of collagenolytic activity by collagenase

2007 ◽  
Vol 41 (1) ◽  
pp. 16-22 ◽  
Author(s):  
B. Madhan ◽  
G. Krishnamoorthy ◽  
J. Raghava Rao ◽  
Balachandran Unni Nair
Keyword(s):  
Green Tea ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Collagenolytic Activity

Abstract 3684: Differential mechanisms of green tea polyphenols-induced apoptosis in human prostate cancer cells: Role of p53.

2013 ◽  
Author(s):  
Karishma Gupta ◽  
Vijay S. Thakur ◽  
Natarajan Bhaskaran ◽  
Akbar Nawab ◽  
Melissa A. Babcook ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Green Tea ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Prostate Cancer Cells ◽  
Induced Apoptosis
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