scholarly journals Theranostic Nanoparticles and Their Spectrum in Cancer

2020 ◽  
Author(s):  
Anca Onaciu ◽  
Ancuta Jurj ◽  
Cristian Moldovan ◽  
Ioana Berindan-Neagoe
Keyword(s):  
Theranostic Nanoparticles

scholarly journals Drug Delivery: Immune Cell-Mediated Biodegradable Theranostic Nanoparticles for Melanoma Targeting and Drug Delivery (Small 10/2017)

Small ◽  
2017 ◽  
Vol 13 (10) ◽  
Author(s):  
Zhiwei Xie ◽  
Yixue Su ◽  
Gloria B. Kim ◽  
Erhan Selvi ◽  
Chuying Ma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Immune Cell ◽  
Theranostic Nanoparticles

Localized Delivery of Theranostic Nanoparticles and High‐Energy Photons using Microneedles‐on‐Bioelectronics

2021 ◽  
pp. 2100425
Author(s):  
Youngsik Lee ◽  
Taegyu Kang ◽  
Hye Rim Cho ◽  
Gil Ju Lee ◽  
Ok Kyu Park ◽  
...  
Keyword(s):  
High Energy ◽  
Theranostic Nanoparticles ◽  
Localized Delivery

Hitchhiking Nanoparticles: Mesenchymal Stem Cell-Mediated Delivery of Theranostic Nanoparticles

2021 ◽  
Author(s):  
Dominyka Dapkute ◽  
Marijus Pleckaitis ◽  
Danute Bulotiene ◽  
Dainius Daunoravicius ◽  
Ricardas Rotomskis ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Theranostic Nanoparticles

scholarly journals Functional Nanoparticles for Tumor Penetration of Therapeutics

Pharmaceutics ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 193 ◽  
Author(s):  
Yu-Lin Su ◽  
Shang-Hsiu Hu
Keyword(s):  
Therapeutic Efficacy ◽  
Tumor Heterogeneity ◽  
Interstitial Fluid ◽  
Fluid Pressure ◽  
Drug Particle ◽  
Tumor Penetration ◽  
Functional Nanoparticles ◽  
Particle Penetration ◽  
Enhanced Permeability And Retention ◽  
Theranostic Nanoparticles

Theranostic nanoparticles recently received great interest for uniting unique functions to amplify therapeutic efficacy and reduce side effects. Despite the enhanced permeability and retention (EPR) effect, which amplifies the accumulation of nanoparticles at the site of a tumor, tumor heterogeneity caused by the dense extracellular matrix of growing cancer cells and the interstitial fluid pressure from abnormal angiogenesis in the tumor inhibit drug/particle penetration, leading to inhomogeneous and limited treatments. Therefore, nanoparticles for penetrated delivery should be designed with different strategies to enhance efficacy. Many strategies were developed to overcome the obstacles in cancer therapy, and they can be divided into three main parts: size changeability, ligand functionalization, and modulation of the tumor microenvironment. This review summarizes the results of ameliorated tumor penetration approaches and amplified therapeutic efficacy in nanomedicines. As the references reveal, further study needs to be conducted with comprehensive strategies with broad applicability and potential translational development.

scholarly journals Targeted Imaging and Therapy of Brain Cancer Using Theranostic Nanoparticles

2010 ◽  
Vol 7 (6) ◽  
pp. 1921-1929 ◽  
Author(s):  
Mahaveer Swaroop Bhojani ◽  
Marcian Van Dort ◽  
Alnawaz Rehemtulla ◽  
Brian D. Ross
Keyword(s):  
Brain Cancer ◽  
Targeted Imaging ◽  
Theranostic Nanoparticles

pH-Sensitive Theranostic Nanoparticles for Targeting Bacteria with Fluorescence Imaging and Dual-Modal Antimicrobial Therapy

2018 ◽  
Vol 1 (11) ◽  
pp. 6187-6196 ◽  
Author(s):  
Peng Liu ◽  
Li Qun Xu ◽  
Gang Xu ◽  
Dicky Pranantyo ◽  
Koon-Gee Neoh ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Antimicrobial Therapy ◽  
Ph Sensitive ◽  
Theranostic Nanoparticles

scholarly journals Ultralong tumor retention of theranostic nanoparticles with short peptide-enabled active tumor homing

2019 ◽  
Vol 6 (9) ◽  
pp. 1845-1853 ◽  
Author(s):  
Lihua Li ◽  
Yao Lu ◽  
Zefeng Lin ◽  
Angelina S. Mao ◽  
Ju Jiao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Tumor ◽  
Short Peptide ◽  
Highly Efficient ◽  
Bimodal Imaging ◽  
Theranostic Nanoparticles ◽  
Tumor Homing ◽  
Homing Peptide ◽  
Tumor Retention

A short breast tumor-homing peptide can guide the theranostic nanoparticles to the tumors and enable their ultralong tumor retention, leading to highly efficient targeted breast cancer CT/MRI bimodal imaging and photothermal-chemotherapy.

Self-assembly of paramagnetic amphiphilic copolymers for synergistic therapy

2020 ◽  
Vol 8 (31) ◽  
pp. 6866-6876 ◽  
Author(s):  
Zhiliang Gao ◽  
Weiwei Mu ◽  
Yuan Tian ◽  
Yimao Su ◽  
Huanli Sun ◽  
...  
Keyword(s):  
Self Assembly ◽  
Amphiphilic Copolymers ◽  
Dual Mode ◽  
Theranostic Nanoparticles

Theranostic nanoparticles composed of amphiphilic paramagnetic polymers are assembled for dual mode imaging and synergistic therapy.

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