scholarly journals Chemotherapy-Induced Nausea and Vomiting

2021 ◽  
Author(s):  
Elisabetta Di Liso
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Common Adverse Effect ◽  
Multiple Organ ◽  
Nausea And Vomiting ◽  
Life Outcomes ◽  
National Guidelines ◽  
Related Factors ◽  
Chemotherapy Agents

Chemotherapy-induced nausea and vomiting is a common adverse effect in cancer patients that not only impacts quality of life, but also treatment outcomes. The prevalence of nausea and vomiting is related to several factors, including the emetogenicity of the chemotherapy regimen, the dose and rate of administration of the chemotherapy agents, various environmental triggers and patient-related factors. The pathogenesis involves multiple organ systems, central nervous system, gastrointestinal tract and neurotransmitters. Clinical management should include a complete assessment of nausea and vomiting to investigate the possible etiology and the pharmacologic approach should involve agents that target each of these pathways and neurotransmitters. Various national guidelines provide recommendations for the prevention and management of CINV and combining these evidence-based strategies into clinical practice is crucial l to improve morbidity and quality-of-life outcomes among cancer patients.

Assessing the impact of chemotherapy-induced nausea and vomiting on patients’ quality of life: An Arabic version of the Functional Living Index-Emesis

2021 ◽  
pp. 107815522199844
Author(s):  
Abdullah M Alhammad ◽  
Nora Alkhudair ◽  
Rawan Alzaidi ◽  
Latifa S Almosabhi ◽  
Mohammad H Aljawadi
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Arabic Language ◽  
Nausea And Vomiting ◽  
Cancer Center ◽  
Arabic Version ◽  
Patient Reported ◽  
Arabic Speaking ◽  
The Impact

Introduction Chemotherapy-induced nausea and vomiting is a serious complication of cancer treatment that compromises patients’ quality of life and treatment adherence, which necessitates regular assessment. Therefore, there is a need to assess patient-reported nausea and vomiting using a validated scale among Arabic speaking cancer patient population. The objective of this study was to translate and validate the Functional Living Index-Emesis (FLIE) instrument in Arabic, a patient-reported outcome measure designed to assess the influence of chemotherapy-induced nausea and vomiting on patients’ quality of life. Methods Linguistic validation of an Arabic-language version was performed. The instrument was administered to cancer patients undergoing chemotherapy in a tertiary hospital's cancer center in Saudi Arabia. Results One-hundred cancer patients who received chemotherapy were enrolled. The participants’ mean age was 53.3 ± 14.9 years, and 50% were female. Half of the participants had a history of nausea and vomiting with previous chemotherapy. The Cronbach coefficient alpha for the FLIE was 0.9606 and 0.9736 for nausea and vomiting domains, respectively, which indicated an excellent reliability for the Arabic FLIE. The mean FLIE score was 110.9 ± 23.5, indicating no or minimal impact on daily life (NIDL). Conclusions The Arabic FLIE is a valid and reliable tool among the Arabic-speaking cancer population. Thus, the Arabic version of the FLIE will be a useful tool to assess the quality of life among Arabic speaking patients receiving chemotherapy. Additionally, the translated instrument will be a useful tool for future research studies to explore new antiemetic treatments among cancer patients.

scholarly journals Treatment of Chemotherapy-induced Nausea in Cancer Patients

2010 ◽  
Vol 06 (02) ◽  
pp. 14
Author(s):  
Julie L Ryan ◽  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Metabolic Disorders ◽  
Nausea And Vomiting ◽  
Daily Functioning ◽  
Evidence Based ◽  
Nutritional Depletion

For over 30 years, chemotherapy-induced nausea and vomiting have been the most severe and troublesome symptoms for cancer patients receiving chemotherapy. Unresolved chemotherapy-induced nausea and vomiting can lead to metabolic disorders, dehydration, nutritional depletion and oesophageal tears, and can reduce the daily functioning and quality of life of and interfere with treatment schedules. Despite the widespread use of antiemetics, chemotherapy-induced nausea continues to be problematic. Unlike vomiting, nausea is a subjective and unobservable phenomenon, making it extremely difficult to accurately assess and treat. Current research suggests that management of chemotherapy-induced nausea should focus on treating the symptoms before they occur rather than after they develop. This article highlights evidence-based interventions for the treatment of chemotherapy-related nausea.

The effect of gender on health-related quality of life and related factors in post-lobectomy lung-cancer patients

2015 ◽  
Vol 19 (3) ◽  
pp. 292-300 ◽  
Author(s):  
Nai-Wen Chang ◽  
Kuan- Chia Lin ◽  
Wen-Hu Hsu ◽  
Shih-Chun Lee ◽  
James Yi-Hsin Chan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Related Factors ◽  
Lung Cancer Patients ◽  
Related Quality ◽  
Health Related

PROMIS evaluation for head and neck cancer patients: A comprehensive quality-of-life outcomes assessment tool

2014 ◽  
Vol 124 (6) ◽  
pp. 1368-1376 ◽  
Author(s):  
Robert J. Stachler ◽  
Lonni R. Schultz ◽  
David Nerenz ◽  
Kathleen L. Yaremchuk
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Assessment Tool ◽  
Outcomes Assessment ◽  
Life Outcomes ◽  
Quality Of Life Outcomes

Antiemesis

2007 ◽  
Vol 5 (1) ◽  
pp. 12 ◽  
Author(s):  
_ _
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Nausea And Vomiting ◽  
Poor Adherence ◽  
Chemotherapy Treatment ◽  
Radiation Induced ◽  
Recent Version

Chemotherapy-induced nausea and vomiting (emesis) can significantly affect a patient's quality of life, leading to poor adherence with further chemotherapy treatment. In addition, nausea and vomiting can result in other serious complications and deterioration of the patient's status. These guidelines explore the prevention, treatment, and management of various types of emesis experienced by cancer patients, such as breakthrough, radiation-induced, and anticipatory. For the most recent version of the guidelines, please visit NCCN.org

Subgroups of Advanced Cancer Patients Clustered by Their Symptom Profiles: Quality-of-Life Outcomes

2011 ◽  
Vol 14 (11) ◽  
pp. 1246-1253 ◽  
Author(s):  
Amna Husain ◽  
Jeff Myers ◽  
Debbie Selby ◽  
Barbara Thomson ◽  
Edward Chow
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Life Outcomes ◽  
Advanced Cancer Patients ◽  
Symptom Profiles ◽  
Quality Of Life Outcomes
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