Antiemesis

2007 ◽  
Vol 5 (1) ◽  
pp. 12 ◽  
Author(s):  
_ _
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Nausea And Vomiting ◽  
Poor Adherence ◽  
Chemotherapy Treatment ◽  
Radiation Induced ◽  
Recent Version

Chemotherapy-induced nausea and vomiting (emesis) can significantly affect a patient's quality of life, leading to poor adherence with further chemotherapy treatment. In addition, nausea and vomiting can result in other serious complications and deterioration of the patient's status. These guidelines explore the prevention, treatment, and management of various types of emesis experienced by cancer patients, such as breakthrough, radiation-induced, and anticipatory. For the most recent version of the guidelines, please visit NCCN.org

Assessing the impact of chemotherapy-induced nausea and vomiting on patients’ quality of life: An Arabic version of the Functional Living Index-Emesis

2021 ◽  
pp. 107815522199844
Author(s):  
Abdullah M Alhammad ◽  
Nora Alkhudair ◽  
Rawan Alzaidi ◽  
Latifa S Almosabhi ◽  
Mohammad H Aljawadi
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Arabic Language ◽  
Nausea And Vomiting ◽  
Cancer Center ◽  
Arabic Version ◽  
Patient Reported ◽  
Arabic Speaking ◽  
The Impact

Introduction Chemotherapy-induced nausea and vomiting is a serious complication of cancer treatment that compromises patients’ quality of life and treatment adherence, which necessitates regular assessment. Therefore, there is a need to assess patient-reported nausea and vomiting using a validated scale among Arabic speaking cancer patient population. The objective of this study was to translate and validate the Functional Living Index-Emesis (FLIE) instrument in Arabic, a patient-reported outcome measure designed to assess the influence of chemotherapy-induced nausea and vomiting on patients’ quality of life. Methods Linguistic validation of an Arabic-language version was performed. The instrument was administered to cancer patients undergoing chemotherapy in a tertiary hospital's cancer center in Saudi Arabia. Results One-hundred cancer patients who received chemotherapy were enrolled. The participants’ mean age was 53.3 ± 14.9 years, and 50% were female. Half of the participants had a history of nausea and vomiting with previous chemotherapy. The Cronbach coefficient alpha for the FLIE was 0.9606 and 0.9736 for nausea and vomiting domains, respectively, which indicated an excellent reliability for the Arabic FLIE. The mean FLIE score was 110.9 ± 23.5, indicating no or minimal impact on daily life (NIDL). Conclusions The Arabic FLIE is a valid and reliable tool among the Arabic-speaking cancer population. Thus, the Arabic version of the FLIE will be a useful tool to assess the quality of life among Arabic speaking patients receiving chemotherapy. Additionally, the translated instrument will be a useful tool for future research studies to explore new antiemetic treatments among cancer patients.

scholarly journals Treatment of Chemotherapy-induced Nausea in Cancer Patients

2010 ◽  
Vol 06 (02) ◽  
pp. 14
Author(s):  
Julie L Ryan ◽  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Metabolic Disorders ◽  
Nausea And Vomiting ◽  
Daily Functioning ◽  
Evidence Based ◽  
Nutritional Depletion

For over 30 years, chemotherapy-induced nausea and vomiting have been the most severe and troublesome symptoms for cancer patients receiving chemotherapy. Unresolved chemotherapy-induced nausea and vomiting can lead to metabolic disorders, dehydration, nutritional depletion and oesophageal tears, and can reduce the daily functioning and quality of life of and interfere with treatment schedules. Despite the widespread use of antiemetics, chemotherapy-induced nausea continues to be problematic. Unlike vomiting, nausea is a subjective and unobservable phenomenon, making it extremely difficult to accurately assess and treat. Current research suggests that management of chemotherapy-induced nausea should focus on treating the symptoms before they occur rather than after they develop. This article highlights evidence-based interventions for the treatment of chemotherapy-related nausea.

Adult Cancer Pain

2007 ◽  
Vol 5 (8) ◽  
pp. 824
Author(s):  
_ _
Keyword(s):  
Quality Of Life ◽  
Clinical Practice ◽  
Cancer Pain ◽  
National Comprehensive Cancer Network ◽  
Cancer Patients ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Cancer Network ◽  
Recent Version

Pain is one of the most common symptoms associated with cancer and one of the symptoms patients fear most; unrelieved pain denies them comfort and greatly affects their activities, motivation, interactions with family and friends, and overall quality of life. The importance of relieving pain and availability of effective therapies make it imperative that clinicians caring for cancer patients to be adept at assessing and treating cancer pain. The National Comprehensive Cancer Network Adult Cancer Pain Clinical Practice Guidelines in Oncology acknowledge the range of complex decisions faced in caring for these patients. As a result, they provide dosing guidelines for NSAIDs, opioids, and adjuvant analgesics. They also provide specific suggestions for escalating opioid dosage, managing opioid toxicity, and when and how to proceed to other techniques to manage cancer pain. For the most recent version of the guidelines, please visit NCCN.org

Fatigue control in metastatic colon cancer treated with capecitabine and oxaliplatin.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19628-e19628
Author(s):  
Fernanda Maris Peria ◽  
Lilian Andrade Sá ◽  
Harley Francisco Oliveira ◽  
Josiane Cheli Vettori ◽  
Daniela Pretti da Cunha Tirapelli ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colon Cancer ◽  
Cancer Patients ◽  
Palliative Chemotherapy ◽  
Large Population ◽  
Concurrent Chemotherapy ◽  
Metastatic Colon Cancer ◽  
Chemotherapy Treatment ◽  
Chi Squared

e19628 Background: Fatigue is one of the most frequent symptoms in cancer patients, characterized by profound fatigue that is not relieved by rest. This symptom can be identified at the time of diagnosis and could affects up to 90% of patients undergoing cancer treatment. There are some instruments available in the literature that can characterize the presence of fatigue through clinical questioning. Methods: Considering the large population of patients with metastatic colorectal cancer treated with chemotherapy and the prevalence of fatigue in these patients, this study evaluated the presence of fatigue in 27 metastatic colon cancer patients before the first, second, third and fourth cycles of fist line palliative chemotherapy regimen containing CAPOX (capecitabine and oxaliplatin) by applying the evaluation questionnaire FACIT-F fatigue. Results: The results post Friedman chi-squared test demonstrated that there was no improvement of fatigue during these four cycles of CAPOX palliative chemotherapy (p=0,2574). The FACIT-G analysis demonstrated no worsening of quality of life (p=0,2411) during and between the four cycles of chemo. All different parameters included in FACIT-F questionnaires: emotional (p=0,2629), physical (p=0,3199), familiar (p=0,1456), functional (p=0,8662) and specific fatigue topic (p=0,7569) confirmed no difference between the cycles. Conclusions: Despite the metastatic stage of colon cancer patients and concurrent chemotherapy treatment, there was no fatigue improvement during the four first CAPOX chemo cycles courses and there was the maintenance of quality of life.

scholarly journals Efficacy and Costs of Two Forms of Stress Management Training for Cancer Patients Undergoing Chemotherapy

2002 ◽  
Vol 20 (12) ◽  
pp. 2851-2862 ◽  
Author(s):  
Paul B. Jacobsen ◽  
Cathy D. Meade ◽  
Kevin D. Stein ◽  
Thomas N. Chirikos ◽  
Brent J. Small ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Usual Care ◽  
Stress Management ◽  
Cancer Patients ◽  
Psychosocial Interventions ◽  
Management Training ◽  
The Self ◽  
Chemotherapy Treatment ◽  
Stress Management Training

PURPOSE: Professionally administered psychosocial interventions have been shown to improve the quality of life of cancer patients undergoing chemotherapy. The present study sought to improve access to psychosocial interventions during chemotherapy treatment by evaluating the efficacy and costs of a patient self-administered form of stress management training that requires limited professional time or experience to deliver. PATIENTS AND METHODS: Four hundred eleven patients about to start chemotherapy were randomly assigned to receive usual psychosocial care only, a professionally administered form of stress management training, or a patient self-administered form of stress management training. Quality-of-life assessments were conducted before randomization and before the second, third, and fourth treatment cycles. Intervention costs were estimated from both payer and societal perspectives. RESULTS: Compared with patients who received usual care only, patients receiving the self-administered intervention reported significantly (P ≤ .05) better physical functioning, greater vitality, fewer role limitations because of emotional problems, and better mental health. In contrast, patients who received the professionally administered intervention fared no better in terms of quality of life than patients receiving usual care only. Costs of the self-administered intervention were estimated to be 66% (from a payer perspective) to 68% (from a societal perspective) less than the average costs of professionally administered psychosocial interventions for patients starting chemotherapy. CONCLUSION: Evidence regarding the efficacy and favorable costs of self-administered stress management training suggests that this intervention has the potential to greatly improve patient access to psychosocial intervention during chemotherapy treatment.

scholarly journals Effects of Behavioral Activation on the Quality of Life and Emotional State of Lung Cancer and Breast Cancer Patients During Chemotherapy Treatment

2017 ◽  
Vol 43 (2) ◽  
pp. 151-180 ◽  
Author(s):  
Concepción Fernández-Rodríguez ◽  
Erica Villoria-Fernández ◽  
Paula Fernández-García ◽  
Sonia González-Fernández ◽  
Marino Pérez-Álvarez
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Lung Cancer ◽  
Cancer Patients ◽  
Behavioral Activation ◽  
Emotional State ◽  
Control Group ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment

Research suggests that the progressive abandonment of activities in cancer patients are related to depression and worse quality of life. Behavioral activation (BA) encourages subjects to activate their sources of reinforcement and modify the avoidance responses. This study assesses the effectiveness of BA in improving quality of life and preventing emotional disorders during chemotherapy treatment. One sample of lung cancer patients and another of breast cancer patients were randomized into a BA experimental group (E.G.lung/4sess. n = 50; E.G.breast/6sess. n = 33) and a control group (C.G.lung/4sess. n = 40; C.G.breast/6sess. n = 35), respectively. In each session and in follow-ups (3/6/9 months), all participants completed different assessment scales. The results converge to show the effectiveness of BA, encouraging cancer patients to maintain rewarding activities which can activate their sources of day-to-day reinforcement and modify their experience avoidance patterns. BA appears to be a practical intervention which may improve social and role functioning and the emotional state of cancer patients during chemotherapy treatment.

Development And Validation Of A Voice Script For Telephone Administration Of THE EORTC QLQ-C30

2021 ◽  
Author(s):  
Claire Piccinin ◽  
Madeline Pe ◽  
Dagmara Kuliś ◽  
James W. Shaw ◽  
Sally J. Wheelwright ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Task Force ◽  
Intraclass Correlation ◽  
Nausea And Vomiting ◽  
Self Report ◽  
Equivalence Testing ◽  
The Voice ◽  
Telephone Administration

Abstract Purpose The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life-Core Questionnaire (QLQ-C30) is a widely used generic self-report measure of health-related quality of life (HRQOL) for cancer patients. However, no validated voice script for interviewer-led telephone administration was previously developed that could be used as an alternative to self-completion. The aim of this study was to develop a voice script for interviewer administration via telephone. Methods Following guidelines from the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) PRO Mixed Modes Good Research Practices Task Force, a randomised cross-over equivalence study, including cognitive debriefing, was conducted to assess equivalence between paper and telephone administration modes. Assuming an expected intraclass correlation coefficient (ICC) of 0.70 and a minimally acceptable level of 0.50, a sample size of 63 was required. Results Cognitive interviews with five cancer patients found the voice script to be clear and understandable. Due to a protocol deviation in the first wave of testing, only 26 patients were available for analyses. A second wave of recruitment was conducted, adding 37 patients (n=63; mean age 55.48; 65.1% female). ICCs for mode comparison ranged from 0.72 (nausea and vomiting, 95% CI 0.48-0.86) to 0.90 (global health status/QoL, 95% CI 0.80-0.95; pain, 95% CI 0.79-0.95; constipation, 95% CI 0.80-0.95). For paper versus phone, all ICCs were above 0.70, except nausea and vomiting (95% CI 0.55). For phone versus paper, all ICCs were above 0.70. Conclusions The equivalence testing results support the voice script’s validity for administration of the QLQ-C30 via telephone.

Antiemesis Clinical Practice Guidelines in Oncology

2004 ◽  
Vol 2 (5) ◽  
pp. 470 ◽  
Keyword(s):  
Functional Ability ◽  
Performance Status ◽  
Wound Dehiscence ◽  
Chemotherapeutic Agents ◽  
Nausea And Vomiting ◽  
Nutrient Depletion ◽  
Chemotherapy Treatment ◽  
Anticancer Treatment ◽  
Recent Version

Chemotherapy-induced nausea and vomiting (emesis) can significantly affect a patient's quality of life, leading to poor adherence with further chemotherapy treatment. In addition, nausea and vomiting can result in metabolic imbalances, degeneration of self-care and functional ability, nutrient depletion, anorexia, decline of the patient's performance status and mental status, wound dehiscence, esophageal tears, and withdrawal from potentially useful or curative anticancer treatment. The incidence and severity of nausea and/or vomiting in patients receiving chemotherapy are affected by numerous factors, including (1) the specific chemotherapeutic agents used, (2) dosage, (3) the schedule and route of administration, and (4) individual patient variability. Approximately 70% to 80% of all cancer patients receiving chemotherapy experience emesis, and 10% to 44% experience anticipatory emesis. For the most recent version of the guidelines, please visit NCCN.org

scholarly journals Evaluation of the quality of life of cancer patients undergoing chemotherapy

Rev Rene ◽  
2022 ◽  
Vol 23 ◽  
pp. e71133
Author(s):  
Eliana Aparecida Carlos ◽  
José Adriano Borgato ◽  
Danielle Cristina Garbuio
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Nausea And Vomiting ◽  
Cross Sectional ◽  
Social And Emotional ◽  
Financial Difficulties ◽  
Student’S T

Objective: to assess the quality of life of cancer patients undergoing chemotherapy. Methods: a cross-sectional study carried out in the chemotherapy sector with 51 patients able to answer the data collection instruments. For the analyses, we adopted the variance analysis and Student’s t. Results: the health score indicated moderate quality of life and the symptoms nausea and vomiting, diarrhea, and dyspnea were the most present. The scores of the global health scale showed differences between age groups and presence of metastasis; diarrhea and financial difficulties showed differences with respect to gender; pain was more cited by those who did not undergo surgery; insomnia and nausea and vomiting were related to the time of treatment. Conclusion: participants had moderate overall health scores and the main functional levels affected by the treatment were social and emotional.

scholarly journals Chemotherapy-Induced Nausea and Vomiting

2021 ◽  
Author(s):  
Elisabetta Di Liso
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Common Adverse Effect ◽  
Multiple Organ ◽  
Nausea And Vomiting ◽  
Life Outcomes ◽  
National Guidelines ◽  
Related Factors ◽  
Chemotherapy Agents

Chemotherapy-induced nausea and vomiting is a common adverse effect in cancer patients that not only impacts quality of life, but also treatment outcomes. The prevalence of nausea and vomiting is related to several factors, including the emetogenicity of the chemotherapy regimen, the dose and rate of administration of the chemotherapy agents, various environmental triggers and patient-related factors. The pathogenesis involves multiple organ systems, central nervous system, gastrointestinal tract and neurotransmitters. Clinical management should include a complete assessment of nausea and vomiting to investigate the possible etiology and the pharmacologic approach should involve agents that target each of these pathways and neurotransmitters. Various national guidelines provide recommendations for the prevention and management of CINV and combining these evidence-based strategies into clinical practice is crucial l to improve morbidity and quality-of-life outcomes among cancer patients.

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