scholarly journals Recent Advances in the Diagnosis and Management of Herpetic Keratitis

2021 ◽  
Author(s):  
Anna Nowińska
Keyword(s):  
Quality Of Life ◽  
Optical Coherence Tomography ◽  
Confocal Microscopy ◽  
Herpetic Keratitis ◽  
Diagnosis And Treatment ◽  
Optical Coherence ◽  
Slit Lamp ◽  
Quality Of Vision ◽  
Methods Of Treatment

The chapter is focused on one of the major cause of keratitis - Herpetic keratitis, its epidemiology, natural course, clinical forms, prognosis, diagnosis and treatment. The estimated global incidence of HSV keratitis is roughly 1,5 million, including 40,000 new cases of each year. Patients are usually affected in the early decades of live, therefore the disease has a severe impact on quality of life and quality of vision in young, productive adults. The author describes the detailed corneal characteristics, provides slit lamp photographs, optical coherence tomography scans and confocal microscopy results of different forms of the HSV keratitis: epithelial, stromal, necrotizing and endothelial. The chapter also discusses recent methods of diagnosis based on PCR testing as well as established and future methods of treatment based on the latest research results.

Management of refractory macular hole: a case report

2021 ◽  
pp. 94-95
Author(s):  
E.A. Krupina ◽  
◽  
O.A. Pavlovsky ◽  
E.A. Larina ◽  
◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Silicone Oil ◽  
Functional Results ◽  
Early Postoperative Period ◽  
Optical Coherence ◽  
Corrected Visual Acuity ◽  
Quality Of Vision ◽  
Air Tamponade

Purpose. Evaluation of the results of the use of Autologous Conditioned Plasma in Management refractory macular hole. Materials and methods. We examined рatient B., 56 years old, with a refractory macular hole (MH), which did not close after two operations. Earlier, the patient underwent cataract phacoemulsification with IOL implantation. Along with traditional methods of examination, optical coherence tomography was performed. Before the operation, Autologous Conditioned Рlasma (ACP) was prepared by centrifuging the patient's blood. After removing the silicone oil, the AСР was injected of the MH zone. The operation was completed with a gas-air tamponade. After the operation, recommended position was "face down" for a day. Results. In the early postoperative period, during biomicroscopy, MH was closure. 2 weeks after surgery, on optical coherence tomography (OCT) there MH was closure. Her best-corrected visual acuity (BCVA) the maximum corrected was 0.01 to 0.15. Patient said about the improvement in the quality of vision and a decrease in metamorphopsies. Conclusion. The use of AСР in the Management of refractory MH is an effective method with good anatomical and functional results. Keywords: refractory macular hole, Autologous Conditioned Plasma, optical coherence tomography, anatomical result.

scholarly journals Association of Glaucoma-Related, Optical Coherence Tomography–Measured Macular Damage With Vision-Related Quality of Life

2017 ◽  
Vol 135 (7) ◽  
pp. 783 ◽  
Author(s):  
Alisa J. Prager ◽  
Donald C. Hood ◽  
Jeffrey M. Liebmann ◽  
C. Gustavo De Moraes ◽  
Lama A. Al-Aswad ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Related Quality

scholarly journals Bedside optical coherence tomography for Terson’s syndrome screening in acute subarachnoid hemorrhage: a pilot study

2019 ◽  
Vol 130 (2) ◽  
pp. 517-524 ◽  
Author(s):  
Ciro Ramos-Estebanez ◽  
Maryo Kohen ◽  
Jonathan Pace ◽  
Alireza Bozorgi ◽  
Sunil Manjila ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Optical Coherence Tomography ◽  
Subarachnoid Hemorrhage ◽  
Pilot Study ◽  
Acute Phase ◽  
Depressed Mood ◽  
Potential Role ◽  
Optical Coherence

OBJECTIVEApproximately 10% of patients with subarachnoid hemorrhage (SAH) become permanently, legally blind. The average cost of lifetime support and unpaid taxes for each blind person amounts to approximately $900,000. This study evaluates the feasibility and potential role of bedside optical coherence tomography (OCT) in Terson’s syndrome (TS) in patients with acute SAH (aSAH) and its potential role in blindness prevention.METHODSThe authors conducted an open-label pilot study, in which 31 patients with an angiographic diagnosis of aSAH were first screened for TS with dilated funduscopy and then with OCT in the acute phase and at 6-week follow-up visits. Outpatient mood assessments (Patient Health Questionnaire–depression module, Hamilton Depression Scale), and quality of life general (NIH Patient-Reported Outcomes Measurement Information System) and visual scales (25-item National Eye Institute Visual Functioning Questionnaire) were measured at 1 and 6 weeks after discharge. Exclusion criteria included current or previous history of severe cataracts, severe diabetic retinopathy, severe macular degeneration, or glaucoma.RESULTSOCT identified 7 patients with TS, i.e., a 22.6% incidence in our aSAH sample: 7 in the acute phase, including a large retinal detachment that was initially missed by funduscopy and diagnosed by OCT in follow-up clinic. Dilated retinal funduscopy significantly failed to detect TS in 4 (57.1%) of these 7 cases. Intraventricular hemorrhage was significantly more common in TS cases (85.7% vs 25%). None of the participants experienced any complications from OCT examinations. Neither decreased quality of life visual scale scores nor a depressed mood correlated with objective OCT pathological findings at the 6-week follow-up after discharge. There were no significant mood differences between TS cases and controls.CONCLUSIONSOCT is the gold standard in retinal disease diagnosis. This pilot study shows that bedside OCT examination is feasible in aSAH. In this series, OCT was a safe procedure that enhanced TS detection by decreasing false-negative/inconclusive funduscopic examinations. It allows early diagnosis of macular holes and severe retinal detachments, which require acute surgical therapy to prevent legal blindness. In addition, OCT aids in ruling out potential false-positive visual deficits in individuals with a depressed mood at follow-up.

Clinical case of a comorbid patient with arterial hypertension

2020 ◽  
pp. 31-39
Author(s):  
Ella Polozova ◽  
Vsevolod Skvortsov ◽  
Olga Radaykina ◽  
Mariya Narvatkina ◽  
Anastasiya Seskina ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Arterial Hypertension ◽  
Clinical Picture ◽  
Clinical Case ◽  
Diagnosis And Treatment ◽  
The Moment

The widespread prevalence of comorbid pathology determines the relevance of this problem. Comorbid pathology due to the interaction of diseases, drug pathomorphism, age characteristics of the patient, significantly changes clinical picture and course of the main nosology, affects severity of complications and their nature, significantly affects quality of life and prognosis of patients. Diagnosis and treatment of many diseases is complicated in the conditions of comorbidity. The article presents a clinical case of a comorbid patient with arterial hypertension from the moment of exposure to risk factors and ending with the formation of many concomitant diseases, as an example of trans-nosological comorbidity.

scholarly journals Spectral-domain optical coherence tomography for evaluating palisades of Vogt in ocular surface disorders with limbal involvement

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ying-Yi Chen ◽  
Yi-Chen Sun ◽  
Chia-Ying Tsai ◽  
Hsiao-Sang Chu ◽  
Jo-Hsuan Wu ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ocular Surface ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Slit Lamp ◽  
Ocular Rosacea ◽  
Unilateral Disease ◽  
Healthy Eyes ◽  
Slit Lamp Biomicroscopy ◽  
Sd Oct

AbstractSpectral-domain optical coherence tomography (SD-OCT) has been used to observe the morphology of the palisades of Vogt (POV) with satisfactory resolutions. In this study, we used SD-OCT to examine the microstructure of the POV in ocular surface disorders with limbal involvement. We detect subclinical limbal pathologies based on five parameters, including (1) decreased epithelial thickness, (2) loss of the sharp stromal tip, (3) loss of the smooth epithelial-stromal interface, (4) dilated stromal vessels, and (5) decreased POV density. Eighteen eyes of 10 patients with advancing wavelike epitheliopathy (AWE) and 15 eyes of 9 patients with phlyctenular keratitis/ocular rosacea were recruited. SD-OCT could detect abnormal changes in the POV in 100% of the lesion sites. In presumed-healthy areas of the diseased eyes diagnosed by slit-lamp biomicroscopy, SD-OCT detected abnormal changes in the POV in 100% of the eyes in both groups. In patients with unilateral disease, abnormal changes in the POV were detected by SD-OCT in 50% and 100% of presumed-healthy eyes diagnosed by slit-lamp biomicroscopy in the AWE group and phlyctenular keratitis/ocular rosacea group, respectively. SD-OCT is powerful in detecting POV changes in ocular surface disorders and can provide useful information that cannot be provided by slit-lamp biomicroscopy.

Characteristics of Linear Interstitial Keratitis by In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography

Cornea ◽  
2018 ◽  
Vol 37 (6) ◽  
pp. 785-788
Author(s):  
Aleksandra Petrovic ◽  
Kattayoon Hashemi ◽  
Frank Blaser ◽  
Wolfgang Wild ◽  
George Kymionis
Keyword(s):  
Optical Coherence Tomography ◽  
Confocal Microscopy ◽  
Anterior Segment ◽  
Optical Coherence ◽  
In Vivo Confocal Microscopy ◽  
Interstitial Keratitis

Cytomegalovirus Retinitis: Diagnosis and Treatment

1993 ◽  
Vol 4 (6) ◽  
pp. 322-325 ◽  
Author(s):  
Hunter Maclean ◽  
Baljean Dhillon
Keyword(s):  
Quality Of Life ◽  
Correct Diagnosis ◽  
Cytomegalovirus Retinitis ◽  
Morbidity And Mortality ◽  
Diagnosis And Treatment ◽  
Hiv Positive ◽  
Pathogenic Organism

Cytomegalovirus (CMV) is a non-pathogenic organism in the immunocompetent, but is a major cause of morbidity and mortality amongst patients with AIDS, and the retina is the commonest site of infection1. If left untreated, patients with CMVR will develop disease in their second eye and ultimately become blind2. However, with correct diagnosis and treatment useful vision can be maintained in the majority of cases. Fifteen to 20% of patients with AIDS will contract cytomegalovirus retinitis (CMVR)3−7 and this may be the AIDS-defining diagnosis though more commonly it occurs months after the diagnosis of AIDS. Given the increasing number of HIV positive patients and their longer survival, it is likely that CMVR will become an increasingly prevalent condition. In these patients loss of sight from CMVR has devastating consequences in terms of loss of independence and quality of life and therefore ophthalmologists and physicians should be aware of the presenting characteristics of CMVR, be familiar with therapy and its complications, and be able to recognize relapsing infection.

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