scholarly journals LitCovid-AGAC: cellular and molecular level annotation data set based on COVID-19

2021 ◽  
Vol 19 (3) ◽  
pp. e23
Author(s):  
Sizhuo Ouyang ◽  
Yuxing Wang ◽  
Kaiyin Zhou ◽  
Jingbo Xia

Currently, coronavirus disease 2019 (COVID-19) literature has been increasing dramatically, and the increased text amount make it possible to perform large scale text mining and knowledge discovery. Therefore, curation of these texts becomes a crucial issue for Bio-medical Natural Language Processing (BioNLP) community, so as to retrieve the important information about the mechanism of COVID-19. PubAnnotation is an aligned annotation system which provides an efficient platform for biological curators to upload their annotations or merge other external annotations. Inspired by the integration among multiple useful COVID-19 annotations, we merged three annotations resources to LitCovid data set, and constructed a cross-annotated corpus, LitCovid-AGAC. This corpus consists of 12 labels including Mutation, Species, Gene, Disease from PubTator, GO, CHEBI from OGER, Var, MPA, CPA, NegReg, PosReg, Reg from AGAC, upon 50,018 COVID-19 abstracts in LitCovid. Contain sufficient abundant information being possible to unveil the hidden knowledge in the pathological mechanism of COVID-19.

2020 ◽  
pp. 3-17
Author(s):  
Peter Nabende

Natural Language Processing for under-resourced languages is now a mainstream research area. However, there are limited studies on Natural Language Processing applications for many indigenous East African languages. As a contribution to covering the current gap of knowledge, this paper focuses on evaluating the application of well-established machine translation methods for one heavily under-resourced indigenous East African language called Lumasaaba. Specifically, we review the most common machine translation methods in the context of Lumasaaba including both rule-based and data-driven methods. Then we apply a state of the art data-driven machine translation method to learn models for automating translation between Lumasaaba and English using a very limited data set of parallel sentences. Automatic evaluation results show that a transformer-based Neural Machine Translation model architecture leads to consistently better BLEU scores than the recurrent neural network-based models. Moreover, the automatically generated translations can be comprehended to a reasonable extent and are usually associated with the source language input.


2021 ◽  
Author(s):  
Xinxu Shen ◽  
Troy Houser ◽  
David Victor Smith ◽  
Vishnu P. Murty

The use of naturalistic stimuli, such as narrative movies, is gaining popularity in many fields, characterizing memory, affect, and decision-making. Narrative recall paradigms are often used to capture the complexity and richness of memory for naturalistic events. However, scoring narrative recalls is time-consuming and prone to human biases. Here, we show the validity and reliability of using a natural language processing tool, the Universal Sentence Encoder (USE), to automatically score narrative recall. We compared the reliability in scoring made between two independent raters (i.e., hand-scored) and between our automated algorithm and individual raters (i.e., automated) on trial-unique, video clips of magic tricks. Study 1 showed that our automated segmentation approaches yielded high reliability and reflected measures yielded by hand-scoring, and further that the results using USE outperformed another popular natural language processing tool, GloVe. In study two, we tested whether our automated approach remained valid when testing individual’s varying on clinically-relevant dimensions that influence episodic memory, age and anxiety. We found that our automated approach was equally reliable across both age groups and anxiety groups, which shows the efficacy of our approach to assess narrative recall in large-scale individual difference analysis. In sum, these findings suggested that machine learning approaches implementing USE are a promising tool for scoring large-scale narrative recalls and perform individual difference analysis for research using naturalistic stimuli.


2021 ◽  
Author(s):  
Monique B. Sager ◽  
Aditya M. Kashyap ◽  
Mila Tamminga ◽  
Sadhana Ravoori ◽  
Christopher Callison-Burch ◽  
...  

BACKGROUND Reddit, the fifth most popular website in the United States, boasts a large and engaged user base on its dermatology forums where users crowdsource free medical opinions. Unfortunately, much of the advice provided is unvalidated and could lead to inappropriate care. Initial testing has shown that artificially intelligent bots can detect misinformation on Reddit forums and may be able to produce responses to posts containing misinformation. OBJECTIVE To analyze the ability of bots to find and respond to health misinformation on Reddit’s dermatology forums in a controlled test environment. METHODS Using natural language processing techniques, we trained bots to target misinformation using relevant keywords and to post pre-fabricated responses. By evaluating different model architectures across a held-out test set, we compared performances. RESULTS Our models yielded data test accuracies ranging from 95%-100%, with a BERT fine-tuned model resulting in the highest level of test accuracy. Bots were then able to post corrective pre-fabricated responses to misinformation. CONCLUSIONS Using a limited data set, bots had near-perfect ability to detect these examples of health misinformation within Reddit dermatology forums. Given that these bots can then post pre-fabricated responses, this technique may allow for interception of misinformation. Providing correct information, even instantly, however, does not mean users will be receptive or find such interventions persuasive. Further work should investigate this strategy’s effectiveness to inform future deployment of bots as a technique in combating health misinformation. CLINICALTRIAL N/A


JAMIA Open ◽  
2021 ◽  
Vol 4 (3) ◽  
Author(s):  
Craig H Ganoe ◽  
Weiyi Wu ◽  
Paul J Barr ◽  
William Haslett ◽  
Michelle D Dannenberg ◽  
...  

Abstract Objectives The objective of this study is to build and evaluate a natural language processing approach to identify medication mentions in primary care visit conversations between patients and physicians. Materials and Methods Eight clinicians contributed to a data set of 85 clinic visit transcripts, and 10 transcripts were randomly selected from this data set as a development set. Our approach utilizes Apache cTAKES and Unified Medical Language System controlled vocabulary to generate a list of medication candidates in the transcribed text and then performs multiple customized filters to exclude common false positives from this list while including some additional common mentions of the supplements and immunizations. Results Sixty-five transcripts with 1121 medication mentions were randomly selected as an evaluation set. Our proposed method achieved an F-score of 85.0% for identifying the medication mentions in the test set, significantly outperforming existing medication information extraction systems for medical records with F-scores ranging from 42.9% to 68.9% on the same test set. Discussion Our medication information extraction approach for primary care visit conversations showed promising results, extracting about 27% more medication mentions from our evaluation set while eliminating many false positives in comparison to existing baseline systems. We made our approach publicly available on the web as an open-source software. Conclusion Integration of our annotation system with clinical recording applications has the potential to improve patients’ understanding and recall of key information from their clinic visits, and, in turn, to positively impact health outcomes.


10.29007/pc58 ◽  
2018 ◽  
Author(s):  
Julia Lavid ◽  
Marta Carretero ◽  
Juan Rafael Zamorano

In this paper we set forth an annotation model for dynamic modality in English and Spanish, given its relevance not only for contrastive linguistic purposes, but also for its impact on practical annotation tasks in the Natural Language Processing (NLP) community. An annotation scheme is proposed, which captures both the functional-semantic meanings and the language-specific realisations of dynamic meanings in both languages. The scheme is validated through a reliability study performed on a randomly selected set of one hundred and twenty sentences from the MULTINOT corpus, resulting in a high degree of inter-annotator agreement. We discuss our main findings and give attention to the difficult cases as they are currently being used to develop detailed guidelines for the large-scale annotation of dynamic modality in English and Spanish.


Author(s):  
Kaan Ant ◽  
Ugur Sogukpinar ◽  
Mehmet Fatif Amasyali

The use of databases those containing semantic relationships between words is becoming increasingly widespread in order to make natural language processing work more effective. Instead of the word-bag approach, the suggested semantic spaces give the distances between words, but they do not express the relation types. In this study, it is shown how semantic spaces can be used to find the type of relationship and it is compared with the template method. According to the results obtained on a very large scale, while is_a and opposite are more successful for semantic spaces for relations, the approach of templates is more successful in the relation types at_location, made_of and non relational.


10.2196/27386 ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. e27386
Author(s):  
Qingyu Chen ◽  
Alex Rankine ◽  
Yifan Peng ◽  
Elaheh Aghaarabi ◽  
Zhiyong Lu

Background Semantic textual similarity (STS) measures the degree of relatedness between sentence pairs. The Open Health Natural Language Processing (OHNLP) Consortium released an expertly annotated STS data set and called for the National Natural Language Processing Clinical Challenges. This work describes our entry, an ensemble model that leverages a range of deep learning (DL) models. Our team from the National Library of Medicine obtained a Pearson correlation of 0.8967 in an official test set during 2019 National Natural Language Processing Clinical Challenges/Open Health Natural Language Processing shared task and achieved a second rank. Objective Although our models strongly correlate with manual annotations, annotator-level correlation was only moderate (weighted Cohen κ=0.60). We are cautious of the potential use of DL models in production systems and argue that it is more critical to evaluate the models in-depth, especially those with extremely high correlations. In this study, we benchmark the effectiveness and efficiency of top-ranked DL models. We quantify their robustness and inference times to validate their usefulness in real-time applications. Methods We benchmarked five DL models, which are the top-ranked systems for STS tasks: Convolutional Neural Network, BioSentVec, BioBERT, BlueBERT, and ClinicalBERT. We evaluated a random forest model as an additional baseline. For each model, we repeated the experiment 10 times, using the official training and testing sets. We reported 95% CI of the Wilcoxon rank-sum test on the average Pearson correlation (official evaluation metric) and running time. We further evaluated Spearman correlation, R², and mean squared error as additional measures. Results Using only the official training set, all models obtained highly effective results. BioSentVec and BioBERT achieved the highest average Pearson correlations (0.8497 and 0.8481, respectively). BioSentVec also had the highest results in 3 of 4 effectiveness measures, followed by BioBERT. However, their robustness to sentence pairs of different similarity levels varies significantly. A particular observation is that BERT models made the most errors (a mean squared error of over 2.5) on highly similar sentence pairs. They cannot capture highly similar sentence pairs effectively when they have different negation terms or word orders. In addition, time efficiency is dramatically different from the effectiveness results. On average, the BERT models were approximately 20 times and 50 times slower than the Convolutional Neural Network and BioSentVec models, respectively. This results in challenges for real-time applications. Conclusions Despite the excitement of further improving Pearson correlations in this data set, our results highlight that evaluations of the effectiveness and efficiency of STS models are critical. In future, we suggest more evaluations on the generalization capability and user-level testing of the models. We call for community efforts to create more biomedical and clinical STS data sets from different perspectives to reflect the multifaceted notion of sentence-relatedness.


2019 ◽  
Vol 6 ◽  
Author(s):  
Catharina Marie Stille ◽  
Trevor Bekolay ◽  
Peter Blouw ◽  
Bernd J. Kröger

Author(s):  
Subasish Das ◽  
Anandi Dutta ◽  
Tomas Lindheimer ◽  
Mohammad Jalayer ◽  
Zachary Elgart

The automotive industry is currently experiencing a revolution with the advent and deployment of autonomous vehicles. Several countries are conducting large-scale testing of autonomous vehicles on private and even public roads. It is important to examine the attitudes and potential concerns of end users towards autonomous cars before mass deployment. To facilitate the transition to autonomous vehicles, the automotive industry produces many videos on its products and technologies. The largest video sharing website, YouTube.com, hosts many videos on autonomous vehicle technology. Content analysis and text mining of the comments related to the videos with large numbers of views can provide insight about potential end-user feedback. This study examines two questions: first, how do people view autonomous vehicles? Second, what polarities exist regarding (a) content and (b) automation level? The researchers found 107 videos on YouTube using a related keyword search and examined comments on the 15 most-viewed videos, which had a total of 60.9 million views and around 25,000 comments. The videos were manually clustered based on their content and automation level. This study used two natural language processing (NLP) tools to perform knowledge discovery from a bag of approximately seven million words. The key issues in the comment threads were mostly associated with efficiency, performance, trust, comfort, and safety. The perception of safety and risk increased in the textual contents when videos presented full automation level. Sentiment analysis shows mixed sentiments towards autonomous vehicle technologies, however, the positive sentiments were higher than the negative.


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