scholarly journals Relationship Between Selenium Trace and Patient Outcome After Open-Heart Surgery

2020 ◽  
Vol 10 (4) ◽  
Author(s):  
Gohar Eslami ◽  
Roya Salehi ◽  
Hamidreza Samaee ◽  
Vallialah Habibi ◽  
Mohammad Shokrzadeh ◽  
...  
Keyword(s):  
Patient Outcome ◽  
Heart Surgery ◽  
Acute Stress ◽  
Open Heart Surgery ◽  
Selenium Level ◽  
Serum Selenium ◽  
Open Heart ◽  
Duration Of Surgery ◽  
The Relationship ◽  
Serum Selenium Level

Background: Acute stress response to heart surgery can cause major morbidity in patients. The trace of selenium is useful for preventing heart damage. Although the trend of selenium changes is of high importance for body balance, the usefulness of routine use and effectiveness of this element for patients under open-heart surgery is still unclear. Objectives: This study aimed at assessing serum selenium level before and after open-heart surgery and the relationship between selenium trace and patient outcome. Methods: This prospective analytical study was performed on 100 patients undergoing open-heart surgery using cardiopulmonary bypass (CPB). In all patients, the serum level was measured at a predetermined time (before surgery and one and two days after surgery). Then, the relationship between serum selenium and patient outcome was assessed. Results: The mean serum selenium level in patients on admission was 72.90 ± 14.62 μg/L, one day after surgery was 71.20 ± 15.84 μg/L, and two days after surgery was 71.54 ± 15.97 μg/L. Serum selenium levels were inversely and significantly associated with age (r = -0.183; P = 0.034, 013) duration of surgery (r = -221 and P = 0.014), duration of intensive care unit stay (r = 0.204, P = 0.021), and duration of CPB (r = 0.223, P = 013). Conclusions: Based on this study’s results, a low level of selenium can affect patients’ outcomes after open-heart surgery.

scholarly journals Influence of biomarkers level during follow-up when operating under cardiopulmonary bypass

2015 ◽  
Vol 18 (3) ◽  
pp. 39
Author(s):  
Yu. I. Petrishchev ◽  
A. L. Levit ◽  
I. N. Leyderman
Keyword(s):  
Cardiac Surgery ◽  
Length Of Stay ◽  
Plasma Levels ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Cardiac Surgeons ◽  
The Given ◽  
The Relationship

Systemic inflammatory response was first determined in 1980 and cardiac surgeons turned to it in 1996. At present, there are a lot of publications on this issue, however, the extent of operation and duration of CPB are considered in clinical practice as crucial indicators of severity of patient's condition following cardiac surgery. In our study we tried to look at this problem from a different perspective and draw a parallel between the severity of patient's condition resulting from operational trauma and CPB. We included 48 patients who under-went cardiac surgery under CPB. Plasma levels of procalcitonin (PCT), lactate and interleukin-6 were investigated before the operation, after CPB and at 24 hours. Also revealed was the relationship between the plasma levels of IL-6, lactate and PCT (r = 0.53; p = 0.000 in both cases). The level of PCT at the 3rd stage was found to relate to the duration of CPB (r = 0.4; p = 0.005), ALV (r = 0.44; p = 0.001) and length of stay at ICU (r = 0.53; p = 0.000). We didn't manage to find any relationship between the length of stay at ICU and the duration of CPB. Correlation between the PCT plasma level and the duration of intensive care indicates the importance of dynamics of the given biomarker for early prediction of follow-up course after open-heart surgery.

scholarly journals DOES PREOPERATIVE ANXIETY AFFECT EARLY OUTCOMES OF OPEN-HEART SURGERY?

2021 ◽  
Author(s):  
Zeki Talas ◽  
Muhip Kanko ◽  
Şadan Yavuz Prof ◽  
Sibel Gür ◽  
Burhan Küçük ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Postoperative Complications ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Preoperative Anxiety ◽  
Open Heart ◽  
High Anxiety ◽  
Hamilton Anxiety Scale ◽  
Anxiety Levels ◽  
The Relationship

Aim: We aim to determine the preoperative anxiety levels of patients with open-heart surgery and examine the relationship between anxiety levels and postoperative complications. Material and Methods: In our prospective study, 200 patients who will undergo open-heart surgery preoperative anxiety levels were measured using the Hamilton anxiety scale (HAM-A). Anxiety levels and the development of complications were investigated. Results: Preoperative anxiety was more common in females (p=0.001). The length of stay in the intensive care unit (p=0.006) and the hospital stay (p=0.005) were found to be longer in patients with high anxiety. It was observed that high preoperative anxiety severity increased the risk of developing postoperative complications (p=0.000024). Conclusion: We can say that preoperative anxiety, which is not considered very important, is seen more frequently than expected for patients who will undergo open-heart surgery. In our study, it was observed that high anxiety levels increased the risk of postoperative complications.

Relationship between serum lactate and ionized calcium in open-heart surgery.

1986 ◽  
Vol 32 (10) ◽  
pp. 1849-1853 ◽  
Author(s):  
J Toffaletti ◽  
R H Christenson ◽  
S Mullins ◽  
R E Harris
Keyword(s):  
Linear Regression ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Blood Gases ◽  
Serum Lactate ◽  
Ionized Calcium ◽  
Open Heart ◽  
Total Calcium ◽  
Before And After ◽  
The Relationship

Abstract We studied 16 patients undergoing open-heart surgery and heart-lung bypass, to examine the relationship between ionized calcium and lactate. Blood was sampled at successive stages of the operation for measurement of ionized and total calcium, lactate, blood gases, pH, hematocrit, and other constituents. We found that correlations between ionized calcium and lactate were positive and statistically significant (p less than 0.05), both among and within patients. The linear regression of ionized calcium on lactate remained highly significant (p less than 0.0001) after adjustment for variability among patients and across operative stages as well as after correction for pH and hemodilution. The significant regressions between calcium and lactate, both before and after administration of calcium, indicate a relationship for calcium and lactate in patients undergoing open-heart surgery.

scholarly journals The Relationship Between Performance Indicators and Readmission of Patients With Open Heart Surgery: A Case Study in Iran

2019 ◽  
Vol 4 (2) ◽  
pp. 62-67
Author(s):  
Parvin Ebrahimi ◽  
Mohammadali Taghi Nattaj Darzi Naghibi ◽  
Soudabeh Vatankhah ◽  
Ghassem Faghanzadeh Ganji
Keyword(s):  
Teaching Hospital ◽  
Performance Indicators ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Patient Readmission ◽  
Open Heart ◽  
Cross Sectional ◽  
Statistical Population ◽  
The North ◽  
The Relationship

Background: Open heart surgery is a prevalent therapeutic intervention for cardiovascular diseases. Significant adverse effects occur after heart surgery, one of which is patient readmission to the hospital. Objective: The present study aimed to determine the relationship between performance indicators and the readmission of patients with open heart surgery in a teaching hospital in Iran. Methods: This study was performed using a cross-sectional and descriptive method with a retrospective approach. Data was collected on a data collection form. The statistical population of this study comprised all patients who underwent open heart surgery from mid-September 2015 to mid-September 2016 in a teaching hospital in the north of Iran (n=849). Those patients readmitted to the hospital within 90 days after discharge, based on a review of patient records, were included in the study. Descriptive statistics and Spearman correlation coefficient were used for data analysis by SPSS 20. Results: Among the patients who had open heart surgery in the selected hospital, 12.5% were readmitted within 90 days after discharge. The most important reasons for readmission in this study were infection in surgery place (25.8%), pleural effusion (18.7%), warfarin toxicity (9.8%), and tamponade (8.9%). There were inverse relationships between patient readmission and the two performance indicators of bed occupancy percentage (r = -0.594, P=0.042) and bed turnover rate (r = -0.664, P=0.018). There were no statistically significant relationships between any of the other indicators (length of stay, mortality, and bed turnover interval) and readmission rate (P>0.1). Conclusion: Hospital authorities can use these results for bed management and targeting interventions to reduce costs and readmissions as a measure of hospital quality. However, further research into readmission factors in other hospitals is recommended.

scholarly journals The Relation Of Intraoperative Renal Oxygen Saturation Change With Postoperative Acute Kidney Injury

2021 ◽  
Author(s):  
Mustafa Emre Gürcü ◽  
Atakan Erkılınç ◽  
Pınar Karaca Baysal ◽  
Fatih Yılmaz ◽  
Tuncer Koçak
Keyword(s):  
Acute Kidney Injury ◽  
Cardiopulmonary Bypass ◽  
Oxygen Saturation ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Kidney Injury ◽  
Left Ventricular Ejection ◽  
Open Heart ◽  
The Relationship ◽  
Renal Oxygen

Objective: Acute kidney injury seen in 25-30 % of the cases after open heart surgery where cardiopulmonary bypass was performed, is one of the most important factors that affect the success of the on- pump open heart surgery by increasing the rates of postoperative morbidity, and mortality. Near infrared spectroscopy (NIRS) is a noninvasive monitoring that frequently used method that allows correction of imbalances in oxygen supply to the brain and vital organs. We aimed to investigate the relationship between renal oxygen saturation values and postoperative acute kidney injury. Method: Fifty patients who underwent on- pump open heart surgery between July 2020 and January 2021 by using cardiopulmonary bypass were included in the study. Demographic data included age, gender, body mass index (BMI), hypertension, diabetes mellitus, chronic obstructive pulmonary disease, other chronic diseases and left ventricular ejection fraction. The definition of acute kidney injury was defined according to the criteria of KDIGO. At the end of the postoperative 48th hour the relationship between intraoperative renal rSO2 changes in patients with or without acute kidney injury was evaluated. Results: Fifty patients were included in the current study. The median (IQR) age of 50 patients was 62 (54.3-66.5), and mostly male patients constituted the study populatio,. When we evaluated the intraoperative data, there were statistically significant differences in changes in renal rSO2 values in patients who had and had not developed postoperative acute kidney injury (-12%, -3%, respectively) (p: 0.001). In the multivariate logistic regression analysis, the change in rSO2 values in the intraoperative period [(from - 10% to 0.5%), OR: 0.18 (0.04-0.76) p: 0.03] were found to be an independent predictor of postoperative acute kidney injury. Conclusion: We found that the decrease of renal rSO2 measurements during surgery may predict the development of acute kidney injury in the postoperative period. We think that renal oxygen saturation monitoring with NIRS is a very effective method for predicting postoperative renal dysfunction, because it is both noninvasive and reflects simultaneous data.

Expression of Plasma microRNA-1/21/ 208a/499 in Myocardial Ischemic Reperfusion Injury

Cardiology ◽  
2015 ◽  
Vol 130 (4) ◽  
pp. 237-241 ◽  
Author(s):  
Wei Yang ◽  
Jianlin Shao ◽  
Xiangfeng Bai ◽  
Guimin Zhang
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
Cardiac Biomarkers ◽  
Open Heart ◽  
Aortic Clamping ◽  
Muscle Band ◽  
Dependent Change ◽  
Time Dependent Change ◽  
Plasma Microrna ◽  
The Relationship

Objectives: We aimed to measure changes in the levels of several miRNAs during open-heart surgery and to investigate the relationship between these changes and cardiac biomarkers. Methods: Creatine kinase-muscle band (CK-MB), cardiac troponin (cTnI) and miRNA (miR-1/21/208a/499) levels were measured during open-heart surgery in 15 patients undergoing combined mitral and aortic valve replacement. The levels of these markers were measured presurgically, 45 min after aortic clamping, 60 min after reperfusion and 24 h after surgery. Results: Significant differences were found in miR-1/208a/499 levels but not in miR-21 levels. miR-1/208a levels were unchanged until 45 min after aortic clamping, increased 60 min after reperfusion (p < 0.001) and decreased significantly 24 h after surgery (p < 0.001). The changes in miR-1/208a levels exhibited a similar pattern to those observed for cTnI and CK-MB, although the changes in miR-208a levels reflected more rapidly than those in miR-1 levels. miR-499 levels decreased after reperfusion (p < 0.001) until 24 h after surgery; these levels were negatively correlated with cTnI and CK-MB levels at all of the time points. Conclusions: A time-dependent change in miR-1/208a/499 levels occurred during open-heart surgery, and these were associated with levels of cTnI and CK-MB. These results reveal that miRNAs may be sensitive biomarkers for I/R injury during open-heart surgery.

Elevated Preoperative Fasting Serum Glucose Levels Increase the Risk of Postoperative Mediastinitis in Patients Undergoing Open Heart Surgery

2003 ◽  
Vol 24 (10) ◽  
pp. 776-778 ◽  
Author(s):  
Stephen J. Wilson ◽  
Daniel J. Sexton
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
Serum Glucose ◽  
Open Heart ◽  
Preoperative Fasting ◽  
Fasting Serum ◽  
Fasting Serum Glucose ◽  
Glucose Levels ◽  
Increased Risk ◽  
The Relationship

AbstractWe conducted a case-control study to investigate the relationship between preoperative fasting serum glucose and postoperative mediastinitis in patients undergoing open heart surgery. Multivariate analysis revealed that a glucose level of 126 mg/dL or greater was associated with a significantly increased risk of mediastinitis (OR, 5.25; P = .002).

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