scholarly journals Urinary Infection Recurrence and Its Related Factors in Urinary Tract Infection

2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Simin Sadeghi Bojd ◽  
Gholamreza Soleimani ◽  
Alireza Teimouri ◽  
Negar Aflakian
Author(s):  
Ased Ali

The realization of the harms resulting from indiscriminate use of antibiotics for minor infection has added impetus to the need to understand better the interaction between urogenital tract epithelium and invading bacteria during the initial stages of urinary tract infection (UTI). It is thought that uropathogenic Escherichia coli clones develop in the gut and migrate across the perineum to the urethra and up into the bladder. The response of the epithelium to bacterial adherence and the evolution of the invading bacteria will then govern the clinical consequences. These can vary between rapid invasion and further migration to produce systemic sepsis to tolerance of the bacteria in a planktonic state in asymptomatic bacteriuria. The key to these differences is the activation of epithelial pathogen-associated molecular pattern receptors by expressed proteins on the bacterial cell wall. Increased understanding of these interactions will lead to non-antibiotic-based strategies for clinical management of urinary infection.


2018 ◽  
Vol 13 ◽  
pp. 81-84 ◽  
Author(s):  
Miriam D. Ismail ◽  
Ihsan Ali ◽  
Savannah Hatt ◽  
Elizabeth A. Salzman ◽  
Anna W. Cronenwett ◽  
...  

2015 ◽  
Vol 9 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Hossein Samadi Kafil ◽  
Ashraf Mohabati Mobarez

Enterococci rank among leading cause of nosocomial bacteremia and urinary tract infection in hospital and community acquired infections. Several traits that may contribute to enhanced virulence have been identified in Enterococci. Extracellular surface protein (Esp) is a virulence factor that contributes in biofilm formation and resistance to environmental stresses. In this study we aimed to determine occurrence ofespinE. faeciumandE. faecalisisolates isolated from urinary tract infections and to investigate whether there is any correlation between presence ofespand antibiotic resistance. One hundred and sixty six isolates were collected from patients with UTI and after identification by biochemical and PCR, antibiotic resistances were examined. The presence ofespwas investigated by primer-specific PCR. 43.3% of isolates identified asE. faeciumand 56.7% asE. faecalis. Theespgene was found in 76.1% ofE. faeciumisolates and 77.9% ofE. faecalisisolate. There were significant correlation betweenesppositiveE. faeciumand resistance to Vancomycin (p<0.01), also inE.faecaliswe found correlation betweenesppositive and resistance to Ampicillin, Chloramphenicol and Tetracycline (p<0.01, p<0.01, p<0.01 respectively). Occurrence ofespin our isolates from urinary tract infection was high that indicates importance of this gene in urinary tract infections and shows importance of ability to forming biofilm and hydrophobicity of surface of Enterococci for causing urinary infection by Enterococci. Also, our finding showed significant correlation between resistance to antibiotics and presence ofespin Enterococci.


1963 ◽  
Vol 1 (13) ◽  
pp. 51-52

Effective antibacterial therapy in many acute and all chronic or recurrent urinary infections requires identification of the infecting bacteria by smear or culture. Since bacteria are often present in the absence of infection, however, quantitative culture is being used increasingly to distinguish urinary tract infection from contamination. It is also recommended as a screening measure in pregnancy, diabetes mellitus, hypertensive disease, and other conditions in which asymptomatic urinary infection is a special danger.


PEDIATRICS ◽  
2016 ◽  
Vol 137 (4) ◽  
pp. e20152490-e20152490 ◽  
Author(s):  
C. P. Nelson ◽  
A. Hoberman ◽  
N. Shaikh ◽  
R. Keren ◽  
R. Mathews ◽  
...  

2013 ◽  
Vol 59 (1) ◽  
pp. 28-30
Author(s):  
Zsuzsanna Moréh ◽  
Lucia Sanda Voicu

Abstract Introduction: Congenital malformations of the urinary system are risk factors for the development of urinary tract infections (UTI). Besides the severity of the malformation, urinary infection is always associated with poor prognosis for these patients. Late discovery of the malformation background, after several urinary tract infection episodes, contributes to the development of chronic pyelonephritis that may lead to chronic renal failure. Material and method: The study involved patients with renal and urinary tract congenital malformations treated at the Pediatric Nephrology Department from Tîrgu Mureș over a period of 6 years, who associated urinary tract infection. Results: Out of the total of 432 patients with congenital malformations of the urinary system, 270 had had at least one or several episode(s) of urinary tract infections in their medical history. Vesico-ureteral reflux and obstructive lesions of the urinary tract were most frequently associated with urinary infections. During the time when no ultrasound screening had been performed, the malformation background was usually diagnosed at the time of the first urinary infection episodes. Conclusions: The incidence of urinary tract infections in patients with renal and urinary tract congenital malformations depends on the type of the underlying malformation, and the time of diagnosis of the malformation background. Prevention of irreversible complications requires early diagnosis of the urinary system malformations that can be performed through ultrasound screening in the neonatal period.


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