scholarly journals Comparison of Maternal Serum Magnesium Level in Pre-eclampsia and Normal Pregnant Women

2013 ◽  
Vol 15 (12) ◽  
Author(s):  
Zohreh Tavana ◽  
Sara Hosseinmirzaei
Author(s):  
Shifali Anand ◽  
Jyoti Hak ◽  
Niveditaa Prashar ◽  
Nikita Gandotra ◽  
Rohini Jaggi

Background: Serum magnesium level in pregnancy is a valuable tool to find out preterm onset of labour. In the asymptomatic group, greater surveillance and administration of steroids, tocolytics and transfer to a higher centre wherever necessary has to be done with mothers with low serum magnesium level. The objective of the study is to find association between serum magnesium levels and women with preterm labour, and to compare these values with those patients who have a term delivery.Methods: The subjects included 100 pregnant women with preterm labour (cases) between 28 and 37 weeks gestation (Group A) and similar number of pregnant women with term labour (controls) between 37 and 40 weeks (Group B). Inclusion criteria for cases was singleton pregnancy, painful uterine contractions more than two in 30 minutes, intact fetal membranes, cervical dilatation (at least 1 cm) and effacement (80%). Serum magnesium levels were done in both the groups. Patients were followed until delivery. Routine antenatal investigations were done. Serum levels of magnesium were estimated by Erba’s semi auto-analyser.Results: 62% patients in Group A were from rural areas. More patients in Group A (70%) were from low socioeconomic class. More women in Group A were anaemic (44%). Mean value of hemoglobin in Group A was 9.93gm/dL. More patients in Group A had muscle cramps (89%). VLBW (<1500gm) neonates were more in Group A (21%). Also, LBW (1500-2499gm) neonates were more in Group A (60%). Mean neonatal birth weight in Group A (1907.3gm) was less. Neonatal morbidity and mortality was observed significantly more in Group A. Mean serum magnesium was less in Group A. Mean serum magnesium levels in primi and multigravida patients were less in Group A. Moreover, mean serum magnesium levels were less in urban and rural patients in Group A. Mean serum magnesium levels were less in normal and overweight patients in Group A. Also, mean serum magnesium levels were less in patients with cervical dilatation <3cm and >3cm in Group A.Conclusions: Low maternal serum magnesium level is associated with preterm labour. Patients with preterm labour have significantly low serum magnesium level when compared with labour at term.


2010 ◽  
Vol 13 (7) ◽  
pp. 335-339 ◽  
Author(s):  
S. Khani ◽  
M. Shokrzadeh ◽  
P.k Karamoddin ◽  
S. Shahmohamm

2018 ◽  
Vol 10 (1) ◽  
pp. 10-15
Author(s):  
HL Roy ◽  
S Nargis ◽  
SH Mahmud ◽  
NWB Jahan ◽  
MS Hossain ◽  
...  

Preeclampsia is the most common medical complication of pregnancy associated with increased maternal and infant mortality and morbidity. Reduced serum magnesium level is found to be associated with elevated blood pressure in preeclampsia. The purpose of this cross-sectional study is to evaluate the serum magnesium level in preeclamptic women. For this study 50 preeclamptic patients, with age range 20 to 40 years having gestational age range from 20 to 40 weeks and 50 age and gestational age matched normotensive pregnant women having no proteinuria were enrolled. Serum magnesium was measured by colorimetric method. The mean(±SD) age and mean(±SD) gestational age of preeclampsia was not significantly different from those of normotensive pregnant women (p=0.203 and p=0.251 respectively). The mean(±SD) body mass index of the preeclamptic patients was significantly higher compared to that of normotensive pregnant women (p<0.001). The mean(±SD) serum magnesium level was 3.37±2.05 mg/dl in preeclamptic group and 2.87±1.38 mg/dl in normal pregnant women; the level did not differ significantly between the subject of preeclampsia and normal pregnant women (p=0.153). Findings of this study suggest that serum magnesium has no association with preeclampsia.Bangladesh J Med Biochem 2017; 10(1): 10-15


2011 ◽  
Vol 44 (13) ◽  
pp. S45-S46
Author(s):  
Seyed Mohammad Reza Parizadeh ◽  
Ashraf Mohammadzadeh ◽  
Ahmadshah Farhat ◽  
Laeya Valaee ◽  
Mohammad Khajedaluee

Author(s):  
Pranshi Gupta

Background: Hypertensive disorders are major factors responsible for morbidity and mortality in pregnancy and pre-eclampsia is the leading cause. The etiopathology of pre-eclampsia is not known even after significant research done on it. A strong strategy in its management is to try to reduce the incidence and severity by predicting its occurrence. In this study, the effect of serum calcium and serum magnesium levels is being investigated with occurrence pre-eclampsia.Methods: Total 120 pregnant patients attending Tirath Ram Shah Hospital were included in the study. They were divided into two groups namely normotensive and hypertensive of 60 each. The serum calcium and serum magnesium levels were estimated and the correlation of these levels was studied with the pre-eclampsia related factors. The data was analysed by application of statistical test of significance.Results: Mean serum calcium level in the normotensive group was 10.119±1.27 mg/dl while mean serum calcium level in the hypertensive group was 9.461±1.164. Mean serum magnesium level in the normotensive women in the study was 1.979±0.405 mg/dl. In the hypertensive women, mean serum magnesium level was 1.723±0.414 mg/dl.Conclusions: This study shows that low levels of calcium and magnesium are found in serum of pre-eclampsia patients as compared to normotensive cases of the study population. The severity of pre-eclampsia is inversely proportional to the levels of serum calcium and magnesium.


2021 ◽  
Vol 33 (1) ◽  
pp. 58-60
Author(s):  
Heera Lal Roy ◽  
Susmita Nargis ◽  
Farhana Ferdaus

Introduction: There are many Hypertensive disorders in pregnancy like preeclampsia, eclampsia etc. Pre-eclampsia is the most common medical complication of pregnancy associated with increased maternal and infant mortality and morbidity. Some studies have implicated that low serum calcium levels may have a role in pre-eclampsia but other studies failed to find relation between low levels of these trace elements and pre-eclampsia. Materials and Methods: This cross sectional study was carried out in the Department of Biochemistry, Sylhet MAG Osmani Medical College in collaboration with the Department of Obstetrics and Gynaecology, Sylhet MAG Osmani Medical College Hospital during the period from January 2016 to December 2016. This Study was occured in among 31 pre-eclampsia patients, aged 20 to 40 years, and gestational age ranges from 20 to 40 weeks and 31 age matched normotensive non-pregnant women having no proteinuria. Serum magnesium was measured by Colorimetric method. Results: The mean serum magnesium level was 3.24 (±1.42) mg/dl in pre–eclampsia and was 3.30 (±1.5) mg/dl in normal women. The mean serum magnesium level did not differ significantly between the subjects of pre–eclampsia and normal women (t=0; p<.05). Conclusion: The means of both data sets are equal. So we can conclude that there is no significant difference between them. Medicine Today 2021 Vol.33(1): 58-60


2013 ◽  
Vol 25 (1) ◽  
pp. 15-19
Author(s):  
K Nahar ◽  
H Yasmin ◽  
L Shamsuzzaman

Objective: To assess the serum magnesium level of pregnant women with pre-eclampsia and eclampsia in Mymensingh Medical College & Hospital (MMCH).   Materials and Methods: This descriptive cross-sectional study was carried out in the   department of Obstetrics and Gynaecology of Mymensingh Medical College & Hospital (MMCH) and “ Prof. Muhammed Hossain Central Laboratory” of Bangladesh Agricultural University (BAU). The serum magnesium level were estimated in 60 study subjects who were pregnant   women with pre-eclampsia & eclampsia and of 60 control subjects who were the normotensive pregnant women by photometric test using xylidyl blue.   Results: The mean (±SD) serum magnesium of the control and study group were (2.29 ± 0.28 mg/dl) & (1.84 ±0.26 mg/dl) respectively. The difference in serum magnesium level between the two groups was statistically highly significant (p=<0.001). In the study group the mean (±SD) serum magnesium level of the pre-eclamptic & eclamptic groups were (1.9150 ± 0.26 mg/dl) & (1.8063 ±0.25 mg/dl) respectively and the difference between them was also statistically significant (p=<0.05).   Conclusion: From the result it could be concluded that hypomagnesaemia can be said to be one of the etiological factors in pre-eclampsia and eclampsia. Hence by estimating serum magnesium during antenatal period pre-eclampsia can be predicted and eclampsia can be   prevented early. DOI: http://dx.doi.org/10.3329/bjog.v25i1.13725 Bangladesh J Obstet Gynaecol, 2010; Vol. 25(1) : 15-19


Sign in / Sign up

Export Citation Format

Share Document