scholarly journals Nail Changes following Hand-Foot-Mouth Disease in North India

2021 ◽  
Vol 7 (4) ◽  
Author(s):  
Ramesh Choudhary ◽  
Vivek Athwani ◽  
Sunil Gothwal
Keyword(s):  
Mouth Disease ◽  
North India ◽  
Outpatient Clinics ◽  
Common Disease ◽  
Preventive Strategies ◽  
Nail Changes ◽  
Male Preponderance ◽  
Hand Foot Mouth Disease

: Hand-foot-mouth disease (HFMD) is common, but nail changes have not been well described. We described nail changes in HFMD. Nail changes following (HFMD) in two outpatient clinics were assessed over two years. Out of 524 cases of HFMD, 40 patients (7.6%) presented with nail problems, 29 cases had onychomadesis, and 11 cases had Beau’s lines. The median age of the subjects was 36 (15 - 126) months, and slight male preponderance (23:17) was seen. HFMD is a common disease having delayed nail changes also. So identification of and preventive strategies are required to limit complications.

scholarly journals Nail changes secondary to hand-foot-mouth disease

2016 ◽  
Vol 58 (3) ◽  
pp. 287 ◽  
Author(s):  
Nebahat Demet Akpolat ◽  
Nezih Karaca
Keyword(s):  
Mouth Disease ◽  
Nail Changes ◽  
Hand Foot Mouth Disease

scholarly journals The Mechanism of Onychomadesis (Nail Shedding) and Beau’s Lines Following Hand-Foot-Mouth Disease

Viruses ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 522 ◽  
Author(s):  
Hsiu-Hui Chiu ◽  
Ming-Tsan Liu ◽  
Wen-Hung Chung ◽  
Yu-Shien Ko ◽  
Chin-Fang Lu ◽  
...  
Keyword(s):  
Late Complications ◽  
Mouth Disease ◽  
Rt Pcr ◽  
Cutaneous Lesions ◽  
Nail Matrix ◽  
Nail Changes ◽  
Hand Foot Mouth Disease ◽  
Atypical Presentations ◽  
Adult Involvement ◽  
A Minor

Background: Nail changes, including onychomadesis (nail shedding) and Beau’s line, following hand-foot-mouth disease (HFMD) are a common emergence at the stage of late complications of HFMD. However, the exact mechanism is still unknown. Therefore, we conducted this study to elucidate the mechanism of nail changes following HFMD. Methods: We collected 11 patients suffering from onychomadesis following HFMD. Nail samples from all of them were collected. Real time reverse transcription polymerase chain reaction (RT-PCR) and sequencing for human enteroviruses (HEV) were performed. Throat swabs for RT-PCR and sequencing for HEV were performed for three cases. Results: RT-PCR demonstrated the presence of Coxackievirus A6 (CVA6) in nail samples from three patients and one with Echovirus. Conclusion: In conclusion, we believe that the major cause of onychomadesis following HFMD is that certain novel viruses, mostly CVA6, are virulent and may damage nail matrix. Direct injury caused by cutaneous lesions of HFMD around nail matrix is a minor cause. There are still other virulent HEV which may result in onychomadesis. In addition, the novel strain of CVA6 also causes atypical clinical presentations, such as adult involvement and delayed-onset palmar and plantar desquamation. Physicians should be familiar with atypical presentations caused by novel viruses to avoid misdiagnosis and even inform patients of the possibility of onychomadesis that may take place weeks later to reassure patients.

scholarly journals NAIL CHANGES IN CASE OF ENTEROVIRAL INFECTIONS IN WESTERN UKRAINE: A REPORT OF 34 CASES

2017 ◽  
Author(s):  
O. R. Boyarchuk ◽  
L. A. Volyanska ◽  
O. M. Dyvonyak
Keyword(s):  
Clinical Features ◽  
Clinical Signs ◽  
Gastrointestinal Symptoms ◽  
Median Number ◽  
Mouth Disease ◽  
Cutaneous Lesions ◽  
Enteroviral Infection ◽  
Nail Changes ◽  
Hand Foot Mouth Disease ◽  
Western Ukraine

Background. Enteroviral infections are common infections, mostly affect children. Nail changes of enteroviral infection including transverse ridging (Beau's lines) and nail shedding (onychomadesis) were described in many countries worldwide.The aim of the research was to investigate the clinical features of the infection that was followed by nail changes during its outbreak in summer-autumn 2016 in Ternopil region, Ukraine.Methods. A case report of 34 children with nail changes that were observed in October 2016 in Ternopil region, Ukraine is presented. All patients were from one kindergarten. Nail trauma, periungual dermatitis, significant medication intake history, systemic diseases were excluded. The survey and clinical examination of cases was performed. Faecal samples were obtained from 13 children with onychomadesis.Results. The median age of the exemined children was 3.97±0.78 years. Interval between onsets of enteroviral infection to nail changes varied from 4 to 12 weeks. Clinical signs that preceded nail changes are fever (64.7%), herpangina (32.6%), pharyngitis (17.6%), gastrointestinal symptoms (44.1%), cutaneous lesions (82.4%) as maculopapular, vesicular rash (44.2%) or/and skin desquamation (41.2%). These clinical data indicate preceded enterovirus infection. In 21 (61.8%) patients hand-foot-mouth disease was suggested.Nail changes were presented by Beau's lines and onychomadesis (nail shedding). The number of affected nails varied from 1 to 16, the median number was 4.88±4.09.Conclusions. Our study proved association between the outbreak of onychomadesis (nail shedding) and enteroviral infection, mainly hand-foot-mouth disease, during summer-autumn 2016 in Western Ukraine (Ternopil region). Enteroviral infection was followed by onychomadesis in 4-12 weeks. Clinical features of enteroviral infection were very variable, with prevalence of cutaneous lesions.More studies are necessary to determine the serotype of the virus that causes onychomadesis.

Gianotti-Crosti syndrome and atypical hand-foot-mouth disease: two distinct entities or two manifestation of the same infection?

2020 ◽  
Vol 155 (1) ◽  
Author(s):  
Elisabetta Venturini ◽  
Luisa Galli ◽  
Elena Chiappini ◽  
Maurizio De Martino ◽  
Andrea Bassi
Keyword(s):  
Mouth Disease ◽  
Hand Foot Mouth Disease

scholarly journals Epidemiological Analysis, Detection, and Comparison of Space-Time Patterns of Beijing Hand-Foot-Mouth Disease (2008–2012)

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e92745 ◽  
Author(s):  
Jiaojiao Wang ◽  
Zhidong Cao ◽  
Daniel Dajun Zeng ◽  
Quanyi Wang ◽  
Xiaoli Wang ◽  
...  
Keyword(s):  
Space Time ◽  
Mouth Disease ◽  
Epidemiological Analysis ◽  
Time Patterns ◽  
Hand Foot Mouth Disease

A Study on Prevalence and Seasonal Distribution of Dengue at a Tertiary Care Centre of North India

Healthline ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 100-107
Author(s):  
Arti Agrawal ◽  
Vikas Kumar ◽  
Sanjeev Kumar ◽  
Neha K Mani
Keyword(s):  
Monsoon Season ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Seasonal Distribution ◽  
North India ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Post Monsoon ◽  
Post Monsoon Season ◽  
Male Preponderance

Introduction: Dengue virus infection is a major public health issue prevalent in tropical and sub-tropical countries all over the world mostly in urban and semi-urban areas. WHO estimates about 50-100 million dengue infections worldwide every year. The present study is aimed to assess the prevalence and seasonal distribution of dengue disease during three consecutive years from 2016-2018 at a tertiary care centre of North India. Method: This is an observational retrospective study conducted on total 6,481 clinical suspected cases referred from indoor and outdoor departments of Medicine and Pediatrics of one of the medical colleges of Agra during the period from 1st January 2016 to 31st December 2018. Results: The maximum positivity was recorded in the year 2016 (16.66%), followed by 2017 (14.07%) and 2018(13.56%).Our study shows male preponderance with maximum cases in the year 2018 was recorded in the month of October (22.75%) whereas the lowest in the month of May (1.96%). Most of the cases were in the age group 0-30 years with a male preponderance. The outbreak occurred during the months of August to November indicating vector transmission in the monsoon and post-monsoon season. Conclusion: From the analysis, this study reflects that the numbers of dengue cases in 2016 were maximum and outnumbered the dengue cases among three consecutive years from 2016 to 2018. The peak in dengue positivity was observed during September to October. As this disease affects the population in the monsoon and post monsoon months therefore continuous monitoring of dengue infection is important during the post-monsoon season.

Effectiveness of Educational Communication in Knowledge, Attitude, and Practice to Hand-Foot-Mouth Disease Prevention of Mother Having Children Under 5 Years Old

2021 ◽  
Vol 104 (8) ◽  
pp. 1229-1234
Keyword(s):  
Disease Prevention ◽  
Educational Communication ◽  
Mouth Disease ◽  
Control Group ◽  
Children Under Five ◽  
Under Five ◽  
Attitude And Practice ◽  
Hand Foot Mouth Disease ◽  
The Right ◽  
Knowledge Attitude And Practice

Background: Hand-foot-mouth disease (HFMD) is an infectious disease that mainly occurs in children under five years old. Vietnam is a developing country with high prevalence of the disease outbreak every year. Can Tho City, Co Do District had the highest incidence of children under five years old acquired HFMD. Objective: 1) To determine the factors correlating with knowledge, attitude, and practice in HFMD prevention of mothers having children under five years old, and 2) to evaluate the alteration in knowledge, attitude, and practice in prevention HFMD of mothers having children under five years old after intervention with health educational communication. Materials and Methods: Community intervention study was done in 420 subjects. At first, all the participants would do the questionnaire and practicing assessment. Then, the participants were divided into two groups, the intervened group for educational communication, and the control group with no intervention. The intervention included three steps, 1) training knowledge and skills for medical staffs and collaborators, 2) providing information about HFMD for the mothers, 3) broadcasting information leaflets to the subjects’ house every month. The assessment in awareness, attitude, and practice would be performed again after one month. The present study staff achieved approval from the Science and Educating Council of Can Tho University of Medicine and Pharmacy. In addition, the present study also received the agreement from The People’s Committee of Co Do District. Results: The present study results shows that 23.3% of mothers had the right knowledge, 50.5% of mothers had the right attitude, and 17.4% of mothers with children under five years of age had the right disease prevention practice. There was an association between education level of mothers with children under five years of age with knowledge, attitude, and practice in disease prevention. After intervention, knowledge of the mothers in the intervened group improved more than 2.79 times, right attitude more than 2.84 times, and practice improvement more than 1.83 times in compared with the control group. Conclusion: Educational communication plays an important role in HFMD disease prevention through increasing the awareness, opinion, and disease prevention of the mothers who directly take care of the under five years old children. Keywords: Hand-foot-mouth disease; Knowledge; Attitudes; Practices; Effective intervention

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