scholarly journals A clinical study on multiple primary malignant tumors associated with colorectal cancer.

1990 ◽  
Vol 23 (10) ◽  
pp. 2370-2375 ◽  
Author(s):  
Norihiro Yuasa ◽  
Yuji Nimura ◽  
Naokazu Hayakawa ◽  
Junichi Kamiya ◽  
Shoji Maeda ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Clinical Study ◽  
Malignant Tumors ◽  
Multiple Primary

scholarly journals Clinical study on multiple primary malignant tumors in patients with oral cancer.

1997 ◽  
Vol 9 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Mikio Nakashima ◽  
Satoru Ozeki ◽  
Michiyo Saitou ◽  
Junkichi Takaki ◽  
Masamichi Ohishi
Keyword(s):  
Clinical Study ◽  
Oral Cancer ◽  
Malignant Tumors ◽  
Multiple Primary

Multiple primary colorectal cancer: Clinical aspects

2016 ◽  
Vol 88 (8) ◽  
pp. 53-58
Author(s):  
N V Soldatkina ◽  
O I Kit ◽  
Yu A Gevorkyan ◽  
A G Milakin
Keyword(s):  
Colorectal Cancer ◽  
Malignant Tumors ◽  
Morphological Characteristics ◽  
Primary Diagnosis ◽  
Clinical Aspects ◽  
Colorectal Tumors ◽  
Primary Tumors ◽  
Multiple Primary ◽  
Colon And Rectum ◽  
Metachronous Colorectal Cancer

Aim. To define some clinical characteristics of synchronous and metachronous colorectal cancer (CRC). Materials and methods. The investigation was concerned with the data of 150 patients with T1—4N0—2M0—1 multiple primary CRC. The clinical, biological, and morphological characteristics of synchronous and metachronous tumors were analyzed. Results. Multiple primary tumors were 6.01% of all the cases of CRC. There was a preponderance of synchronous CRC (63.75%) with the tumor localized in the sigmoid colon and rectum. In women, synchronous colorectal tumors were more often concurrent with breast tumors; metachronous ones were detected after treatment for genital tumors. In men, synchronous colorectal tumors were more frequently concurrent with kidney cancer; metachronous ones were identified after treatment for gastric cancer. Conclusion. The found characteristics of multiple primary colorectal tumors may be taken in account in programs for both primary diagnosis and follow-up after treatment for malignant tumors, which will be able to improve the early detection of cancer patients and their treatment results.

scholarly journals Clinical study on 18 cases of multiple primary malignant tumors including oral cancer.

1994 ◽  
Vol 40 (7) ◽  
pp. 785-791
Author(s):  
Mie KATAGIRI ◽  
Tomohiro ANDO ◽  
Hiroaki KATAUMI ◽  
Hiroyuki KANEKO ◽  
Yasubumi MARUOKA ◽  
...  
Keyword(s):  
Clinical Study ◽  
Oral Cancer ◽  
Malignant Tumors ◽  
Multiple Primary

MULTIPLE PRIMARY MALIGNANT TUMORS

1960 ◽  
Vol 70 (12) ◽  
pp. 1647???1657
Author(s):  
PHILLIP A. DIBBLE ◽  
ROBERT G. CHAMBERS
Keyword(s):  
Malignant Tumors ◽  
Multiple Primary

scholarly journals Tumor budding as a prognostic criterion of colorectal cancer

Pathologia ◽  
2021 ◽  
Vol 18 (3) ◽  
pp. 346-351
Author(s):  
I. I. Yakovtsova ◽  
V. M. Cheverda ◽  
O. V. Dolhaia ◽  
A. S. Yakymenko ◽  
I. V. Ivakhno
Keyword(s):  
Colorectal Cancer ◽  
Malignant Tumors ◽  
Fatal Outcome ◽  
Tumor Budding ◽  
Lethal Outcome ◽  
Regional Lymph Nodes ◽  
Prognostic Features ◽  
Group I ◽  
Prognostic Criterion ◽  
The Moment

Colorectal cancer (CRC) is the second leading cause of mortality among cancers after malignant tumors of respiratory system. One of the most significant prognostic features of CRC is tumor budding (TB), which isn’t widely implemented in clinical practice. The aim of this research: to find the prognostic criteria of recurrence and lethal outcome of CRR IIA and IIIB stages (рТ3N0-2M0), the ratio of tumors with certain differentiation in groups of research was taken equal. Material and methods. The group I was formed from primary CRC without recurrences. The main relapse-free survival time was 5 years (62.5 ± 16.5 months). The ІІ group – primary CRC with recurrences; ІІА – with recurrences during 5 years from the moment when the tumor was removed, without fatal outcome; ІІВ – with recurrences and lethal outcome from genera­lization of tumor process during 5 years from the moment when the tumor was removed. The microslides of CRC were made by using the standard methods. Results. TB was identified in 46.66 % (28/60) of CRC рТ3N0-2M0. The direct relationship between tumor grade and presence of TB was found (Р < 0.05), but TB didn’t define differentiation of the CRC. There was a statistically significant relationship between TB and metastatic spreading of CRC to regional lymph nodes (Р < 0.001). Metastasis was associated with 3 stage of TB, absence of metastasis was typical for CRC without TB. The tendency was found in a larger number of cases of the CRC with TB 3 stage among recurring CRC compared with CRC without recurrence, mainly due to the ІІВ group of the research. Inverse correlation between TB stage and time of recurrence appearance was found (Р < 0.05). TB in central tumor sites was followed by presence and higher stage of TB in peripheral tumor sites (Р < 0.05), that can be taken into account during biopsies of CRC. Conclusions. TB is a prognostic criterion of metastasis and time of recurrence appearance for CRC рТ3N0-2M0, which is mostly typical for tumors in patients with recurrences and lethal outcome at the taken equal ratio of tumors by differen­tiation.

scholarly journals Promising Advances in LINC01116 Related to Cancer

2021 ◽  
Vol 9 ◽  
Author(s):  
Yating Xu ◽  
Xiao Yu ◽  
Menggang Zhang ◽  
Qingyuan Zheng ◽  
Zongzong Sun ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Gastric Cancer ◽  
Lung Cancer ◽  
Cancer Colorectal ◽  
Malignant Tumors ◽  
Biological Processes ◽  
Aberrant Expression ◽  
Protein Coding ◽  
Future Studies ◽  
Non Coding Rnas

Long non-coding RNAs (lncRNAs) are RNAs with a length of no less than 200 nucleotides that are not translated into proteins. Accumulating evidence indicates that lncRNAs are pivotal regulators of biological processes in several diseases, particularly in several malignant tumors. Long intergenic non-protein coding RNA 1116 (LINC01116) is a lncRNA, whose aberrant expression is correlated with a variety of cancers, including lung cancer, gastric cancer, colorectal cancer, glioma, and osteosarcoma. LINC01116 plays a crucial role in facilitating cell proliferation, invasion, migration, and apoptosis. In addition, numerous studies have recently suggested that LINC01116 has emerged as a novel biomarker for prognosis and therapy in malignant tumors. Consequently, we summarize the clinical significance of LINC01116 associated with biological processes in various tumors and provide a hopeful orientation to guide clinical treatment of various cancers in future studies.

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