Concept-Match Medical Data Scrubbing

2003 ◽  
Vol 127 (6) ◽  
pp. 680-686 ◽  
Author(s):  
Jules J. Berman

Abstract Context.—In the normal course of activity, pathologists create and archive immense data sets of scientifically valuable information. Researchers need pathology-based data sets, annotated with clinical information and linked to archived tissues, to discover and validate new diagnostic tests and therapies. Pathology records can be used for research purposes (without obtaining informed patient consent for each use of each record), provided the data are rendered harmless. Large data sets can be made harmless through 3 computational steps: (1) deidentification, the removal or modification of data fields that can be used to identify a patient (name, social security number, etc); (2) rendering the data ambiguous, ensuring that every data record in a public data set has a nonunique set of characterizing data; and (3) data scrubbing, the removal or transformation of words in free text that can be used to identify persons or that contain information that is incriminating or otherwise private. This article addresses the problem of data scrubbing. Objective.—To design and implement a general algorithm that scrubs pathology free text, removing all identifying or private information. Methods.—The Concept-Match algorithm steps through confidential text. When a medical term matching a standard nomenclature term is encountered, the term is replaced by a nomenclature code and a synonym for the original term. When a high-frequency “stop” word, such as a, an, the, or for, is encountered, it is left in place. When any other word is encountered, it is blocked and replaced by asterisks. This produces a scrubbed text. An open-source implementation of the algorithm is freely available. Results.—The Concept-Match scrub method transformed pathology free text into scrubbed output that preserved the sense of the original sentences, while it blocked terms that did not match terms found in the Unified Medical Language System (UMLS). The scrubbed product is safe, in the restricted sense that the output retains only standard medical terms. The software implementation scrubbed more than half a million surgical pathology report phrases in less than an hour. Conclusions.—Computerized scrubbing can render the textual portion of a pathology report harmless for research purposes. Scrubbing and deidentification methods allow pathologists to create and use large pathology databases to conduct medical research.

Author(s):  
Augustin-Catalin Iapa ◽  
Vladimir-Ioan Cretu

Identifying or authenticating a computer user are necessary steps to keep systems secure on the network and to prevent fraudulent users from accessing accounts. Keystroke dynamics authentication can be used as an additional authentication method. Keystroke dynamics involves in-depth analysis of how you type on the keyboard, analysis of how long a key is pressed or the time between two consecutive keys. This field has seen a continuous growth in scientific research. In the last five years alone, about 10,000 scientific researches in this field have been published. One of the main problems facing researchers is the small number of public data sets that include how users type on the keyboard. This paper aims to provide researchers with a data set that includes how to type free text on the keyboard by 80 users. The data were collected in a single session via a web platform. The dataset contains 410,633 key-events collected in a total time interval of almost 24 hours. In similar research, most datasets are with texts written by users in English. The language in which the users wrote for this research is Romanian. This paper also provides an extensive analysis of the data set collected and presents relevant information for the analysis of the data set in future research.


Author(s):  
Lior Shamir

Abstract Several recent observations using large data sets of galaxies showed non-random distribution of the spin directions of spiral galaxies, even when the galaxies are too far from each other to have gravitational interaction. Here, a data set of $\sim8.7\cdot10^3$ spiral galaxies imaged by Hubble Space Telescope (HST) is used to test and profile a possible asymmetry between galaxy spin directions. The asymmetry between galaxies with opposite spin directions is compared to the asymmetry of galaxies from the Sloan Digital Sky Survey. The two data sets contain different galaxies at different redshift ranges, and each data set was annotated using a different annotation method. The results show that both data sets show a similar asymmetry in the COSMOS field, which is covered by both telescopes. Fitting the asymmetry of the galaxies to cosine dependence shows a dipole axis with probabilities of $\sim2.8\sigma$ and $\sim7.38\sigma$ in HST and SDSS, respectively. The most likely dipole axis identified in the HST galaxies is at $(\alpha=78^{\rm o},\delta=47^{\rm o})$ and is well within the $1\sigma$ error range compared to the location of the most likely dipole axis in the SDSS galaxies with $z>0.15$ , identified at $(\alpha=71^{\rm o},\delta=61^{\rm o})$ .


2020 ◽  
Vol 6 ◽  
Author(s):  
Jaime de Miguel Rodríguez ◽  
Maria Eugenia Villafañe ◽  
Luka Piškorec ◽  
Fernando Sancho Caparrini

Abstract This work presents a methodology for the generation of novel 3D objects resembling wireframes of building types. These result from the reconstruction of interpolated locations within the learnt distribution of variational autoencoders (VAEs), a deep generative machine learning model based on neural networks. The data set used features a scheme for geometry representation based on a ‘connectivity map’ that is especially suited to express the wireframe objects that compose it. Additionally, the input samples are generated through ‘parametric augmentation’, a strategy proposed in this study that creates coherent variations among data by enabling a set of parameters to alter representative features on a given building type. In the experiments that are described in this paper, more than 150 k input samples belonging to two building types have been processed during the training of a VAE model. The main contribution of this paper has been to explore parametric augmentation for the generation of large data sets of 3D geometries, showcasing its problems and limitations in the context of neural networks and VAEs. Results show that the generation of interpolated hybrid geometries is a challenging task. Despite the difficulty of the endeavour, promising advances are presented.


2006 ◽  
Vol 39 (2) ◽  
pp. 262-266 ◽  
Author(s):  
R. J. Davies

Synchrotron sources offer high-brilliance X-ray beams which are ideal for spatially and time-resolved studies. Large amounts of wide- and small-angle X-ray scattering data can now be generated rapidly, for example, during routine scanning experiments. Consequently, the analysis of the large data sets produced has become a complex and pressing issue. Even relatively simple analyses become difficult when a single data set can contain many thousands of individual diffraction patterns. This article reports on a new software application for the automated analysis of scattering intensity profiles. It is capable of batch-processing thousands of individual data files without user intervention. Diffraction data can be fitted using a combination of background functions and non-linear peak functions. To compliment the batch-wise operation mode, the software includes several specialist algorithms to ensure that the results obtained are reliable. These include peak-tracking, artefact removal, function elimination and spread-estimate fitting. Furthermore, as well as non-linear fitting, the software can calculate integrated intensities and selected orientation parameters.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Jiawei Lian ◽  
Junhong He ◽  
Yun Niu ◽  
Tianze Wang

Purpose The current popular image processing technologies based on convolutional neural network have the characteristics of large computation, high storage cost and low accuracy for tiny defect detection, which is contrary to the high real-time and accuracy, limited computing resources and storage required by industrial applications. Therefore, an improved YOLOv4 named as YOLOv4-Defect is proposed aim to solve the above problems. Design/methodology/approach On the one hand, this study performs multi-dimensional compression processing on the feature extraction network of YOLOv4 to simplify the model and improve the feature extraction ability of the model through knowledge distillation. On the other hand, a prediction scale with more detailed receptive field is added to optimize the model structure, which can improve the detection performance for tiny defects. Findings The effectiveness of the method is verified by public data sets NEU-CLS and DAGM 2007, and the steel ingot data set collected in the actual industrial field. The experimental results demonstrated that the proposed YOLOv4-Defect method can greatly improve the recognition efficiency and accuracy and reduce the size and computation consumption of the model. Originality/value This paper proposed an improved YOLOv4 named as YOLOv4-Defect for the detection of surface defect, which is conducive to application in various industrial scenarios with limited storage and computing resources, and meets the requirements of high real-time and precision.


1997 ◽  
Vol 1997 ◽  
pp. 143-143
Author(s):  
B.L. Nielsen ◽  
R.F. Veerkamp ◽  
J.E. Pryce ◽  
G. Simm ◽  
J.D. Oldham

High producing dairy cows have been found to be more susceptible to disease (Jones et al., 1994; Göhn et al., 1995) raising concerns about the welfare of the modern dairy cow. Genotype and number of lactations may affect various health problems differently, and their relative importance may vary. The categorical nature and low incidence of health events necessitates large data-sets, but the use of data collected across herds may introduce unwanted variation. Analysis of a comprehensive data-set from a single herd was carried out to investigate the effects of genetic line and lactation number on the incidence of various health and reproductive problems.


2011 ◽  
pp. 24-32 ◽  
Author(s):  
Nicoleta Rogovschi ◽  
Mustapha Lebbah ◽  
Younès Bennani

Most traditional clustering algorithms are limited to handle data sets that contain either continuous or categorical variables. However data sets with mixed types of variables are commonly used in data mining field. In this paper we introduce a weighted self-organizing map for clustering, analysis and visualization mixed data (continuous/binary). The learning of weights and prototypes is done in a simultaneous manner assuring an optimized data clustering. More variables has a high weight, more the clustering algorithm will take into account the informations transmitted by these variables. The learning of these topological maps is combined with a weighting process of different variables by computing weights which influence the quality of clustering. We illustrate the power of this method with data sets taken from a public data set repository: a handwritten digit data set, Zoo data set and other three mixed data sets. The results show a good quality of the topological ordering and homogenous clustering.


2019 ◽  
Vol 8 (2S11) ◽  
pp. 3523-3526

This paper describes an efficient algorithm for classification in large data set. While many algorithms exist for classification, they are not suitable for larger contents and different data sets. For working with large data sets various ELM algorithms are available in literature. However the existing algorithms using fixed activation function and it may lead deficiency in working with large data. In this paper, we proposed novel ELM comply with sigmoid activation function. The experimental evaluations demonstrate the our ELM-S algorithm is performing better than ELM,SVM and other state of art algorithms on large data sets.


2021 ◽  
Vol 14 (11) ◽  
pp. 2369-2382
Author(s):  
Monica Chiosa ◽  
Thomas B. Preußer ◽  
Gustavo Alonso

Data analysts often need to characterize a data stream as a first step to its further processing. Some of the initial insights to be gained include, e.g., the cardinality of the data set and its frequency distribution. Such information is typically extracted by using sketch algorithms, now widely employed to process very large data sets in manageable space and in a single pass over the data. Often, analysts need more than one parameter to characterize the stream. However, computing multiple sketches becomes expensive even when using high-end CPUs. Exploiting the increasing adoption of hardware accelerators, this paper proposes SKT , an FPGA-based accelerator that can compute several sketches along with basic statistics (average, max, min, etc.) in a single pass over the data. SKT has been designed to characterize a data set by calculating its cardinality, its second frequency moment, and its frequency distribution. The design processes data streams coming either from PCIe or TCP/IP, and it is built to fit emerging cloud service architectures, such as Microsoft's Catapult or Amazon's AQUA. The paper explores the trade-offs of designing sketch algorithms on a spatial architecture and how to combine several sketch algorithms into a single design. The empirical evaluation shows how SKT on an FPGA offers a significant performance gain over high-end, server-class CPUs.


Author(s):  
V. Suresh Babu ◽  
P. Viswanath ◽  
Narasimha M. Murty

Non-parametric methods like the nearest neighbor classifier (NNC) and the Parzen-Window based density estimation (Duda, Hart & Stork, 2000) are more general than parametric methods because they do not make any assumptions regarding the probability distribution form. Further, they show good performance in practice with large data sets. These methods, either explicitly or implicitly estimates the probability density at a given point in a feature space by counting the number of points that fall in a small region around the given point. Popular classifiers which use this approach are the NNC and its variants like the k-nearest neighbor classifier (k-NNC) (Duda, Hart & Stock, 2000). Whereas the DBSCAN is a popular density based clustering method (Han & Kamber, 2001) which uses this approach. These methods show good performance, especially with larger data sets. Asymptotic error rate of NNC is less than twice the Bayes error (Cover & Hart, 1967) and DBSCAN can find arbitrary shaped clusters along with noisy outlier detection (Ester, Kriegel & Xu, 1996). The most prominent difficulty in applying the non-parametric methods for large data sets is its computational burden. The space and classification time complexities of NNC and k-NNC are O(n) where n is the training set size. The time complexity of DBSCAN is O(n2). So, these methods are not scalable for large data sets. Some of the remedies to reduce this burden are as follows. (1) Reduce the training set size by some editing techniques in order to eliminate some of the training patterns which are redundant in some sense (Dasarathy, 1991). For example, the condensed NNC (Hart, 1968) is of this type. (2) Use only a few selected prototypes from the data set. For example, Leaders-subleaders method and l-DBSCAN method are of this type (Vijaya, Murthy & Subramanian, 2004 and Viswanath & Rajwala, 2006). These two remedies can reduce the computational burden, but this can also result in a poor performance of the method. Using enriched prototypes can improve the performance as done in (Asharaf & Murthy, 2003) where the prototypes are derived using adaptive rough fuzzy set theory and as in (Suresh Babu & Viswanath, 2007) where the prototypes are used along with their relative weights. Using a few selected prototypes can reduce the computational burden. Prototypes can be derived by employing a clustering method like the leaders method (Spath, 1980), the k-means method (Jain, Dubes, & Chen, 1987), etc., which can find a partition of the data set where each block (cluster) of the partition is represented by a prototype called leader, centroid, etc. But these prototypes can not be used to estimate the probability density, since the density information present in the data set is lost while deriving the prototypes. The chapter proposes to use a modified leader clustering method called the counted-leader method which along with deriving the leaders preserves the crucial density information in the form of a count which can be used in estimating the densities. The chapter presents a fast and efficient nearest prototype based classifier called the counted k-nearest leader classifier (ck-NLC) which is on-par with the conventional k-NNC, but is considerably faster than the k-NNC. The chapter also presents a density based clustering method called l-DBSCAN which is shown to be a faster and scalable version of DBSCAN (Viswanath & Rajwala, 2006). Formally, under some assumptions, it is shown that the number of leaders is upper-bounded by a constant which is independent of the data set size and the distribution from which the data set is drawn.


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