scholarly journals Antifungal activity of Psidium guajava organic extracts against dermatophytic fungi

2012 ◽  
Vol 6 (41) ◽  
pp. 5435-5438 ◽  
Author(s):  
Beatriz Padroacute n Maacute rquez ◽  
Ezequiel Viveros Valdez ◽  
Or ◽  
Azucena ay Caacute rdenas ◽  
Pilar Carranza Rosales
Keyword(s):  
Antifungal Activity ◽  
Psidium Guajava ◽  
Dermatophytic Fungi ◽  
Organic Extracts

scholarly journals EVALUATION OF ANTIFUNGAL POTENTIAL OF ALLIUM AMPELOPRASUM AGAINST FUNGAL PHYTOPATHOGENS

2018 ◽  
Vol 11 (11) ◽  
pp. 129
Author(s):  
Shahid Khan ◽  
Amandeep Kaur ◽  
Neeta Raj Sharma
Keyword(s):  
Chemical Composition ◽  
Antifungal Activity ◽  
Inhibitory Concentration ◽  
Economic Importance ◽  
Allium Ampeloprasum ◽  
Water Extracts ◽  
Maximum Inhibition ◽  
Antifungal Potential ◽  
Organic Extracts ◽  
Fungal Phytopathogens

Objective: Present study evaluates the antifungal potential of Allium ampeloprasum extracts against two phytopathogens of economic importance, namely Alternaria triticina and Magnaporthe oryzae which are found to be one of the greatest threats to wheat and rice crop worldwide.Methods: Four different organic solvents, i.e., water, methanol, acetone, and hexane were used for extract preparation based on the increasing order of polarity. Further, different concentrations of these extracts were used to perform a quantitative assay for measuring the antifungal activity of extracts. Two-way analysis of variance was used to statistically analyze the results through GraphPad Prism v. 7.00.Results: The best results were shown by water extracts with a maximum inhibition of 99.39±0.2% against A. triticina and 99.39±2.2% against M. oryzae. Water extracts gave minimal inhibitory concentration 90 values at 9.94 μg/mL against M. oryzae and at 16.73 μg/mL against A. triticina.Conclusion: Water extracts of A. ampeloprasum have relatively higher potential for being used as an antifungal agent as compared to other organic extracts used in this study. Further study on the chemical composition of A. ampeloprasum water extracts can reveal potent anti-phytopathogenic fungal compounds which can be used to develop biofungicides.

scholarly journals Phenolic composition and medicinal usage of Psidium guajava Linn.: Antifungal activity or inhibition of virulence?

2017 ◽  
Vol 24 (2) ◽  
pp. 302-313 ◽  
Author(s):  
Maria F.B. Morais-Braga ◽  
Joara N.P. Carneiro ◽  
Antonio J.T. Machado ◽  
Débora L. Sales ◽  
Antonia T.L. dos Santos ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Psidium Guajava ◽  
Phenolic Composition

scholarly journals Effects of Medicinal Plant Extracts and Photosensitization on Aflatoxin Producing Aspergillus flavus (Raper and Fennell)

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Loise M. Njoki ◽  
Sheila A. Okoth ◽  
Peter M. Wachira
Keyword(s):  
Antifungal Activity ◽  
Medicinal Plant ◽  
Plant Extracts ◽  
Spinacia Oleracea ◽  
Aflatoxin Production ◽  
Prunus Africana ◽  
Toxigenic Fungi ◽  
Medicinal Plant Extracts ◽  
Organic Extracts ◽  
Zones Of Inhibition

This study was undertaken with an aim of exploring the effectiveness of medicinal plant extracts in the control of aflatoxin production. Antifungal properties, photosensitization, and phytochemical composition of aqueous and organic extracts of fruits from Solanum aculeastrum, bark from Syzygium cordatum, and leaves from Prunus africana, Ocimum lamiifolium, Lippia kituiensis, and Spinacia oleracea were tested. Spores from four-day-old cultures of previously identified toxigenic fungi, UONV017 and UONV003, were used. Disc diffusion and broth dilution methods were used to test the antifungal activity. The spores were suspended in 2 ml of each extract separately and treated with visible light (420 nm) for varying periods. Organic extracts displayed species and concentration dependent antifungal activity. Solanum aculeastrum had the highest zones of inhibition diameters in both strains: UONV017 (mean = 18.50±0.71 mm) and UONV003 (mean = 11.92±0.94 mm) at 600 mg/ml. Aqueous extracts had no antifungal activity because all diameters were below 8 mm. Solanum aculeastrum had the lowest minimum inhibitory concentration at 25 mg/ml against A. flavus UONV017. All the plant extracts in combination with light reduced the viability of fungal conidia compared with the controls without light, without extracts, and without both extracts and light. Six bioactive compounds were analyzed in the plant extracts. Medicinal plant extracts in this study can control conidia viability and hence with further development can control toxigenic fungal spread.

scholarly journals Antifungal Metabolites From Alternaria atrans: An Endophytic Fungus in Psidium guajava

2019 ◽  
Vol 14 (5) ◽  
pp. 1934578X1984411 ◽  
Author(s):  
Zhi Yang ◽  
Wen-Jia Dan ◽  
Yi-Xiao Li ◽  
Guang-Rui Peng ◽  
An-Ling Zhang ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Medicinal Plant ◽  
Inhibitory Activity ◽  
Colletotrichum Gloeosporioides ◽  
Fusaric Acid ◽  
Alternaria Solani ◽  
Psidium Guajava ◽  
Inhibitory Effect ◽  
Solid Culture ◽  
Antifungal Metabolites

Six metabolites (1–6), including 1 new fusaric acid derivative, designated atransfusarin (1), and 5 known compounds, (3 R,6 R)-3-benzyl-6-isopropyl-4-methylmorpholine-2,5-dione (2), daucoterol (3), adenosine (4), cerebroside B (5), and 2,3-dihydroxypropyl ( Z,Z)-9,12-octadecadienate (6), were isolated from the solid culture of an endophytic Alternaria atrans MP-7, associated with the medicinal plant Psidium guajava. The structure of the new compound was elucidated by spectral data. The antifungal test indicated that (3 R,6 R)-3-benzyl-6-isopropyl-4-methylmorpholine-2,5-dione (2) showed obvious inhibitory activity against Alternaria solani, Colletotrichum gloeosporioides, and Phyricularia grisea. Compared to fusaric acid (1a), even though the antifungal activity of atransfusarin (1) against A. solani, C. gloeosporioides, and P. grisea was greatly decreased, its inhibitory effect against Botrytis cinerea was still retained.

scholarly journals Phytochemical Analysis and Antifungal Activity of Ficus Sycomorus L. (Moraceae) Extracts on some Dermatophytic Fungi

2021 ◽  
Vol 6 (1) ◽  
pp. 11-17
Author(s):  
Umar Lawal ◽  
◽  
L. Mansir ◽  
M. G. Sani
Keyword(s):  
Antifungal Activity ◽  
Methanol Extract ◽  
Fungal Infections ◽  
Stem Bark ◽  
Phytochemical Analysis ◽  
Microsporum Canis ◽  
Phytochemical Screening ◽  
Ms Analysis ◽  
Dermatophytic Fungi ◽  
Ficus Sycomorus

Ficus sycomorus L is a large, semi-deciduous spreading savannah tree that belongs to the family (Moraceae) is used by many tribes in the treatments of skin infections. The aim of this study was to carry out phytochemical analysis and antifungal evaluation of F. sycomorus L. stem and leaf Methanol extract on some dermatophytic fungi. The stem and leaf crude extracts were obtained after drying using maceration and percolation with methanol as the solvent. The extract was subjected to qualitative phytochemical screening as well as GC-MS analysis for the presence of bioactive constituents. The antifungal inhibitory effect of the crude stem and leaf extracts was assessed by agar well diffusion methods. The phytochemical screening revealed that the leaves and stem-bark contained secondary metabolites such as tannins, flavonoids, alkaloids, saponins, reducing sugar and steroid. The GC-MS assay showed that the most prevailing compound in the methanolic stem-bark extract was 2, 9, Diazabicyclo (4, 4, 0) decane-3,10 dione, while in the methanolic leaves extract was acetic acid. The anti-dermatophytic assay of the extracts against Microsporum canis and Tricophyton tonsurans showed that the extracts inhibited the fungi with zones of inhibitions ranging from 6.33±0.47 to 24.33±0.47mm with the leaf extract exhibiting higher inhibition zones than the stem extract (p˂0.01). The study shows that both the stem and leaf methanol extract of Ficus sycomorus L possesses antifungal activity and should be considered as a potential antifungal agent in search of newer agents to address dermatophytic fungal infections Key words: Ficus sycomorus L, Phytochemical/GC-MS Analysis, Antifungal activity

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