scholarly journals Follow-up of Application of Plaster-of-Paris Casts for Non-infected Plantar Ulcers in Field Conditions

1970 ◽  
Vol 41 (3) ◽  
Author(s):  
G. SØDERBERG
Keyword(s):  
Field Conditions ◽  
Plaster Of Paris ◽  
Plantar Ulcers

Outcomes of closed reduction in patients with developmental dysplasia of the hip incorporating open psoas and adductor release and using short leg cast

2021 ◽  
Vol 15 (5) ◽  
pp. 1529-1532
Author(s):  
M. S. Abdulqader ◽  
L. J. Khorsheed ◽  
Hwaizi .
Keyword(s):  
Soft Tissue ◽  
Closed Reduction ◽  
Case Series ◽  
Developmental Dysplasia ◽  
Soft Tissue Release ◽  
Plaster Of Paris ◽  
Dysplasia Of The Hip ◽  
Mid Term Results ◽  
Tönnis Grade

Background and objectives: Closed reduction and short leg spica casting are the preferred treatment options for children with developmental dysplasia of the hip. This study aimed to show the efficacy behind a standardized closed reduction for managing patients with developmental dysplasia of the hip with concomitant soft tissue releases when indicated and using a short leg plaster of Paris cast to maintain reduction and reporting mid-term results. Methods: A case series of 95 hips in 84 children aged 6-18 months who had closed reduction, with five years follow up or until next operation, involved in this study. The protocol defines acceptable concentric reduction criteria and the indications for an associated soft tissue release. All the patients were immobilized in a short leg cast for three months. Multiple follow-up radiographs were taken to assess Tönnis grade, Severin grade, acetabular index, and osteonecrosis signs. Results: A total of 48 hips were Tönnis grade 3/4 hips. At one year, 15 reductions couldn’t be maintained, and these patients needed open reduction. Of these 15 failed reductions, 7 patients were Severin 1; others were Severin 2. Of the 80 successful closed reductions, 70 hips were Severin 1. Surgical management for residual dysplasia was offered for 8 hips. Osteonecrosis was seen in 23 hips but was transient in 20. Bilateral hip dislocations and most Tönnis 4 hips were more likely to fail. Two children had severe osteonecrosis. Conclusions: Closed reduction, with subsequent adductor and psoas releases, when indicated and using a short leg plaster of Paris cast for three months, brings about good mid-term results in children with developmental dysplasia of the hip aged 6-18 months. Keywords: Developmental dysplasia of the hip, closed hip reduction, open psoas release, short leg cast.

scholarly journals Early Functional and Radiological Outcomes Between Plaster Cast and Fiberglass Cast in Stable Thoracolumbar Burst Fracture

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Zamzuri Z ◽  
Ariff Ms ◽  
Mohd Fairuz Ad ◽  
Mohd Shukrimi A ◽  
Nazri My
Keyword(s):  
Burst Fracture ◽  
Radiological Outcome ◽  
Thoracolumbar Burst Fracture ◽  
Kyphotic Angle ◽  
Cross Sectional ◽  
Patient’S Satisfaction ◽  
Plaster Of Paris ◽  
Anterior Body ◽  
Body Cast

Introduction: Burst fracture results from compression failure of both the anterior and middle columns under substantial axial loads. Conservative treatment was a method of treatment for fractures without neurological deficit. This cross sectional study was designed to evaluate the functional and radiological outcome of patient with thoracolumbar burst fracture treated conservatively. Methods: 40 cases were recruited from January 2013 till December 2015. They were followed-up with minimum period of 1 year and evaluated for the functional (Oswetry Disbility Index) and radiological outcomes (kyphotic angle deformity and anterior body compression). Results: 20 patients were treated with body cast made form plaster of Paris and remaining 20 patients with fiberglass cast. In plaster of Paris group, mean kyphotic angle deformity at last follow up was 16.60 ± 2.95 with a mean improvement 4.45 degree and anterior body compression at last follow up was 30.35% ± 10.2 with mean improvement of 9.30%. In fiberglass group, mean kyphotic angle deformity at last follow up was 15.55 ± 3.38 with a mean improvement 7.25 degree and anterior body compression at last follow up was 25.90% ± 7.81 with mean improvement of 3.45%. The functional outcome showed Oswetry Disability Index (ODI) score in plaster of Paris group was 23.70 (SD = 7.82) and in fiberglass group was 18.50 (SD = 5.94). Conclusions: Application of body cast using a fiberglass material give better radiological outcome hence less pain, more functional and higher patient’s satisfaction as compared to plaster of Paris.

scholarly journals The Effect of Vaccination with Neospora caninum Live-Frozen Tachyzoites on Abortion Rates of Naturally Infected Pregnant Cows

Vaccines ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 401
Author(s):  
Monica L. Mazuz ◽  
Benjamin Leibovitz ◽  
Igor Savitsky ◽  
Elena Blinder ◽  
Daniel Yasur-Landau ◽  
...  
Keyword(s):  
Vaccine Efficacy ◽  
Neospora Caninum ◽  
Field Conditions ◽  
High Antibody ◽  
Live Attenuated Vaccine ◽  
Attenuated Vaccine ◽  
Antibody Titers ◽  
Positive Results ◽  
Caninum Tachyzoites

Neosporosis is a major cause of abortions in cattle worldwide. Recently a live attenuated vaccine showing promising results in preventing abortions, when administered at mid-pregnancy to seropositive cows, was developed. In this study, vaccination with 2 × 108 live frozen N. caninum tachyzoites (NcIs491) was used to immunize naturally infected seropositive pregnant dairy dams. The study was performed under field conditions in four herds, and a follow-up of three subsequent pregnancies was analyzed. A total of 1136 cows were serologically examined. Total seroprevalence was 41.4%, with 25.1% of the cows having titers of 1:800 or higher. Abortion rates were significantly higher in cows with high antibody titers (≥1:800) for two consecutive pregnancies. Vaccination was administered to 114 out of 285 cows with antibody titers higher than 1:800. Immunization resulted in lower abortion rates at three of the farms. Vaccine efficacy ranged from −19.8% to 75% at different farms, with overall efficacy of 28.4% in all four farms and overall efficacy of 58.2% in the three farms with positive results. Our results showed different vaccine efficacy in studied farms, suggesting that frozen live vaccination may generally be an effective method to control neosporosis in cattle.

scholarly journals Topical 1% Propranolol in Liposomal Gel: A New Adjuvant Tool for Chronic Leprosy Ulcers

2018 ◽  
Vol 12 (1) ◽  
pp. 59-64
Author(s):  
Ayman Abdelmaksoud ◽  
Domenico Bonamonte ◽  
Giuseppe Giudice ◽  
Angela Filoni ◽  
Michelangelo Vestita
Keyword(s):  
Substantial Reduction ◽  
Complete Healing ◽  
Sensory Function ◽  
Surrounding Tissue ◽  
Granulation Tissue Formation ◽  
Recommended Treatment ◽  
Number Of Patients ◽  
Sterile Normal Saline ◽  
Plantar Ulcers

Objective:To evaluate the effects of 1% topical propranolol in liposomal gel in 3 patients with plantar ulcers.Methods:We enrolled 3 patients with 3 ulcers who had completed the WHO recommended treatment regimen. The ulcers were cleaned with sterile normal saline, and 1% topical propranolol in liposomal gel was applied 2 times/day for 3 months, or less if complete healing was reached before. Assessment of ulcer re-epithelization was recorded at baseline, 6 weeks, and 3 and 6 months after initiation of treatment.Results:Response in the form of granulation tissue formation started by the second week. Substantial reduction in size subsequently continued over the next 3 months. Two of the 3 patients showed complete healing of the ulcers at the 6 months follow up. In the 3rdpatient, the ulcer showed only modest signs of healing. Surprisingly, in all patients, the sensory function was restored, particularly in terms of pain. Some motor functional recovery at the ulcer site and surrounding tissue was also documented.Conclusion:To the best of our knowledge, this is the first trial of topical propranolol for the treatment of trophic ulcers of leprosy. This may represent a promising adjuvant therapy for leprosy ulcers, including ulcers of older age. Further studies are warranted with a larger number of patients and a longer period of follow up to determine the ideal candidates and to identify clinical factors predictive of response.

Sensory manifestations of diabetic neuropathies: Anatomical and clinical correlations

2015 ◽  
Vol 39 (1) ◽  
pp. 7-16 ◽  
Author(s):  
Mohamed Kazamel ◽  
Peter J Dyck
Keyword(s):  
Treatment Options ◽  
Diabetic Neuropathies ◽  
Sensory Impairment ◽  
Sensorimotor Polyneuropathy ◽  
Anatomical Basis ◽  
Patients With Diabetes ◽  
Plantar Ulcers ◽  
Anatomical Localization ◽  
Charcot Joints

Background: Diabetes mellitus is among the most common causes of peripheral neuropathy worldwide. Sensory impairment in diabetics is a major risk factor of plantar ulcers and neurogenic arthropathy (Charcot joints) causing severe morbidity and high health-care costs. Objective: To discuss the different patterns of sensory alterations in diabetic neuropathies and their anatomical basis. Study design: Literature review. Methods: Review of the literature discussing different patterns of sensory impairment in diabetic neuropathies. Results: The different varieties of diabetic neuropathies include typical sensorimotor polyneuropathy (lower extremity predominant, length-dependent, symmetric, sensorimotor polyneuropathy presumably related to chronic hyperglycemic exposure, and related metabolic events), entrapment mononeuropathies, radiculoplexus neuropathies related to immune inflammatory ischemic events, cranial neuropathies, and treatment-related neuropathies (e.g. insulin neuritis). None of these patterns are unique for diabetes, and they can occur in nondiabetics. Sensory alterations are different among these prototypic varieties and are vital in diagnosis, following course, treatment options, and follow-up of treatment effects. Conclusions: Diabetic neuropathies can involve any segment of peripheral nerves from nerve roots to the nerve endings giving different patterns of abnormal sensation. It is the involvement of small fibers that causes positive sensory symptoms like pain early during the course of disease, bringing subjects to physician’s care. Clinical Relevance This article emphasizes on the fact that diabetic neuropathies are not a single entity. They are rather different varieties of conditions with more or less separate pathophysiological mechanisms and anatomical localization. Clinicians should keep this in mind when assessing patients with diabetes on the first visit or follow-up.

The Follow Up on Profiled Wire Gasket Development and Testing With Case Studies

2018 ◽  
Author(s):  
Anthony Currie
Keyword(s):  
Case Studies ◽  
Thermal Cycle ◽  
Laboratory Testing ◽  
Field Conditions ◽  
Related Field ◽  
Field Service ◽  
Sealing Performance ◽  
Winding Wire

The paper discusses the development of sealing technology within the organisation with particular emphasis on the gasket manufactured by profiled winding wire. This will be referred to as a PWG. The paper is a continuation of the paper presented in Paris PVP2013-97050 and follow up in PVP2014-28948. It discusses further laboratory testing and briefly describes 4 related field service case studies. The paper details tests which include: Thermal cycle, sealing performance, compression and recovery testing carried out in both laboratory and field conditions. The 4 related studies are based around the use on large flanges, the use in oxygen rich environment, the use in a thermal cyclic environment and on problematic flange corrosion.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

Brief summary of Kleť photographic search programme for minor planets

1999 ◽  
Vol 173 ◽  
pp. 189-192
Author(s):  
J. Tichá ◽  
M. Tichý ◽  
Z. Moravec
Keyword(s):  
Ccd Camera ◽  
Minor Planet ◽  
Minor Planets ◽  
Main Belt

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.

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