scholarly journals A successful healthy live birth from a female patient with hypogonadotropic hypogonadism and oocytes with unusually large cytoplasmic inclusions

2016 ◽  
Vol 20 (1) ◽  
Author(s):  
Candan Iltemir Duvan ◽  
Aslıhan Pekel ◽  
Ummu Gulsum Ercan ◽  
Yuksel Onaran Arıkan
Keyword(s):  
Female Patient ◽  
Live Birth ◽  
Hypogonadotropic Hypogonadism ◽  
Cytoplasmic Inclusions

scholarly journals Chorangioma - A Case Report

2014 ◽  
Vol 14 (2) ◽  
pp. 185-186
Author(s):  
Rehana Khanam ◽  
P.K. Ghosh ◽  
Fauzia Jahan ◽  
Saidur Rahman
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Live Birth ◽  
Microscopic Examination ◽  
Histopathological Examination ◽  
Incidental Finding ◽  
Caesarian Section ◽  
College Hospital ◽  
Medical College ◽  
Clinically Normal

We present a female patient with pregnancy associated with normal live birth and the unusual concomitance of chorangioma. It was an incidental finding during the routine microscopic examination of the placenta of the 30 year multipara whose pregnancy was clinically normal. She was admitted to the Bangladesh Medical College Hospital for labor at 34 weeks gestation. She was investigated thoroughly because of irregular pervaginal bleeding before delivary. Caesarian section was done at 37th weeks of pregnancy. The placenta was found enlarged, irregular and haemorrhagic. Histopathological examination from the sections of specimen was done and diagnosed as Chorangioma. The case is presented as below.DOI: http://dx.doi.org/10.3329/jom.v14i2.19671 J Medicine 2013, 14(2): 185-186

Hypogonadotropic hypogonadism in a female patient previously diagnosed as having waardenburg syndrome due to a sox10 mutation

Endocrine ◽  
2014 ◽  
Vol 49 (2) ◽  
pp. 553-556 ◽  
Author(s):  
Yoko Izumi ◽  
Ikuma Musha ◽  
Erina Suzuki ◽  
Manami Iso ◽  
Tomoko Jinno ◽  
...  
Keyword(s):  
Female Patient ◽  
Hypogonadotropic Hypogonadism ◽  
Waardenburg Syndrome

scholarly journals The mitochondrial DNA content can not predict the embryo viability

2018 ◽  
Author(s):  
M.S. Yong Qiu ◽  
M.S. Songchang Chen ◽  
Chen Dayang ◽  
M.S. Ping Liu ◽  
M.S. Jun Xia ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Female Patient ◽  
Live Birth ◽  
Dna Content ◽  
Birth Rate ◽  
Live Birth Rate ◽  
Embryo Morphology ◽  
Embryo Viability ◽  
Mitochondrial Dna Content ◽  
Chromosome Status

ABSTRACTObjectiveTo investigate whether the mitochondrial DNA content could predict the embryo viabilityDesignRetrospective analysis.SettingReproductive genetics laboratoryPatient(s)A total of 421 biopsied samples obtained from 129 patientsIntervention(s)Embryo biopsies samples underwent whole genome amplification (WGA) and were tested by next generation sequencing (NGS) and array Comparative Genomic Hybridization (aCGH), 30 samples were selected randomly to undergo quantitative real-time polymerase chain reaction (qPCR).Main Outcome Measure(s)Those embryos which obtained the consistent chromosome status determined both aCGH and NGS platform were further classified. We investigated the relationship of mtDNA content with several factors including female patient age, embryo morphology, chromosome status, and live birth rate of both blastocysts and blastomeres.Result(s)A total of 386 (110 blastomeres and 276 blastocysts) out of 399 embryos showed consistent chromosome status outcome. We found no statistically difference was observed in aneuploid and euploid blastocysts (p=0.14), the same phenomenon was observed in aneuploid and euploid blastomeres (p=0.89). Similarly, the mtDNA content was independent of female patient age, embryo morphology and live birth rate.Conclusion(s)The mtDNA content did not provide a reliable prediction of the viability of blastocysts to initiate a pregnancy.

Hypogonadotropic hypogonadism in a female patient with congenital arhinia

2017 ◽  
Vol 30 (1) ◽  
Author(s):  
Janel Darcy Hunter ◽  
Melissa Ann Davis ◽  
Jennifer Rachel Law
Keyword(s):  
Female Patient ◽  
Hypogonadotropic Hypogonadism ◽  
Brain Magnetic Resonance Imaging ◽  
Abdominal Ultrasound ◽  
Sex Steroid ◽  
Laboratory Evaluation ◽  
Delayed Puberty ◽  
Timely Initiation ◽  
Normal Pituitary Gland ◽  
First Case

AbstractThe association of anosmia and congenital hypogonadotropic hypogonadism (CHH) is well described; however, congenital arhinia is a malformation associated with CHH that occurs much more rarely. There have been three reports of male patients with hypogonadism and congenital arhinia in the literature to date. We present the first case of arhinia associated with CHH in a female patient. A 14 years and 8 months female with congenital arhinia presented with delayed puberty. Physical examination and laboratory evaluation were consistent with hypogonadotropic hypogonadism. She had no other hormone deficiencies and brain magnetic resonance imaging demonstrated a normal pituitary gland. Abdominal ultrasound showed a prepubertal uterus and ovaries. She was subsequently started on sex steroid treatment to induce secondary sexual characteristics. This case demonstrates that abnormalities of nasal development may provide an early diagnostic clue to hypogonadotropic hypogonadism, particularly in female patients who would not manifest classic signs of CHH in infancy (micropenis and cryptorchidism). Early diagnosis of CHH and timely initiation of sex steroid therapy is important to prevent comorbidities related to pubertal delay.

Sign in / Sign up

Export Citation Format

Share Document