scholarly journals Xylopia aethiopica ethanol seed extract suppresses Cadmium chloride-induced ovary and gonadotropins toxicity in adult female Wistar rats

2021 ◽  
Vol 25 (2) ◽  
Author(s):  
Elvis.T Godam ◽  
Olugbemi Olaniyan ◽  
Chiwendu D Wofuru ◽  
Clinton D Orupabo ◽  
Kenneth S Ordu ◽  
...  
Keyword(s):  
Adult Female ◽  
Cadmium Chloride ◽  
Wistar Rats ◽  
Seed Extract ◽  
Female Wistar Rats ◽  
Xylopia Aethiopica

scholarly journals The fertility assessment of normal cyclic Wistar rats following the administration of methanolic extract of Portulaca oleracea: an experimental study

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Izuchukwu Azuka Okafor ◽  
Uchenna Somtochukwu Nnamah ◽  
Jude Nnaka
Keyword(s):  
Estrous Cycle ◽  
Adult Female ◽  
Wistar Rats ◽  
Major Effect ◽  
Reproductive Hormones ◽  
Portulaca Oleracea ◽  
High Dose ◽  
Methanolic Extracts ◽  
Cycle Arrest ◽  
Female Wistar Rats

Abstract Background Purslane is a widely distributed shrub used for the treatment of different ailments. The increasing reproductive complications associated with herbal treatments have led to the need to critically evaluate the safety and/or reproductive potentials of commonly used plant extracts. This study investigated the reproductive effect of methanolic extracts of Portulaca oleracea (MEPO) in adult female Wistar rats. Results Group C showed a significant decrease both in relative ovarian weight (p = 0.000), and relative uterine weight (p = 0.037), when compared with the control. There were no significant (p ˃ 0.05) changes in the levels of follicle-stimulating hormone, luteinizing hormone, progesterone, and estradiol. When compared to the control, groups B and C showed abnormal estrous cycle and cycle arrest especially at the metestrus phase with mild congestion of a few blood vessels in the ovary and uterus. Conclusions MEPO may possess some anti-fertility effect, as it disrupts the estrous cycle of adult female Wistar rats; although it has no major effect on the reproductive hormones, uterus, and ovarian histology of adult female Wistar rats. However, high dose consumption should be taken with precaution.

scholarly journals Locomotor sensitization to cocaine in adolescent and adult female Wistar rats

2018 ◽  
Vol 349 ◽  
pp. 158-162 ◽  
Author(s):  
Sydney A. Rowson ◽  
Stephanie L. Foster ◽  
David Weinshenker ◽  
Gretchen N. Neigh
Keyword(s):  
Adult Female ◽  
Wistar Rats ◽  
Locomotor Sensitization ◽  
Female Wistar Rats

Cyantraniliprole impairs reproductive parameters by inducing oxidative stress in adult female wistar rats

2021 ◽  
Author(s):  
Suellen Ribeiro da Silva Scarton ◽  
Felipe Tsuzuki ◽  
Marina Trevizan Guerra ◽  
Dayane Priscila dos Santos ◽  
Aldair Casagrande dos Santos ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adult Female ◽  
Wistar Rats ◽  
Reproductive Parameters ◽  
Female Wistar Rats

Effects of chia (Salvia hispanica L.) on oxidative stress and inflammation in ovariectomized adult female Wistar rats

2019 ◽  
Vol 10 (7) ◽  
pp. 4036-4045 ◽  
Author(s):  
Bárbara Pereira da Silva ◽  
Renata Celi Lopes Toledo ◽  
Marcella Duarte Villas Mishima ◽  
Maria Eliza de Castro Moreira ◽  
Christiane Mileib Vasconcelos ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adult Female ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Lipid Profiles ◽  
Ovariectomized Rats ◽  
High Fat ◽  
Salvia Hispanica ◽  
Female Wistar Rats ◽  
Salvia Hispanica L

The study investigated the influence of chia consumption on inflammation, oxidative stress, and lipid profiles in female ovariectomized rats fed a high-fat diet.

scholarly journals Haematological Study on the Effects of Goko Cleanser (Herbal Mixture) on Adult Female Wistar Rats

2021 ◽  
pp. 8-19
Author(s):  
Darlington Nnamdi Onyejike ◽  
McWilliams, Winifred Chidera ◽  
Mmaju, Chidinma Ifeyinwa ◽  
Okeke, Somadina Nnamdi ◽  
Obiesie, Ifechukwu Justicia ◽  
...  
Keyword(s):  
Adult Female ◽  
Wistar Rats ◽  
The Body ◽  
Control Group ◽  
Herbal Mixture ◽  
Female Wistar Rats ◽  
Group 3 ◽  
Haematological Study ◽  
The Brain ◽  
Herbal Mixtures

Introduction: Goko cleanser is one of the popular herbal mixtures used by the Nigerian populace. This study was carried out to evaluate the effects of this herbal mixture on some haematological parameters of adult female Wistar rats. Methodology: A total of twenty five Wistar rats weighing about 160 – 280g were divided into five groups according to their corresponding weights. The groups were designated as groups 1 – 5. Group 1 served as the control group, while groups 2, 3, 4, and 5 received 1000mg/Kg, 1500mg/Kg, 2000mg/Kg and 4000mg/Kg respectively. Results: The TWBC, PCV, PLATELET count, and RBC and Hb showed a statistically significant (p<0.05) increase for the test groups 2 – 5 when compared to the control group. The body weight had a statistically significant (p<0.05) decrease in groups 2, 4, and 5; while group 3 had a statistically insignificant (p>0.05) decrease. Conclusion and Recommendation: This study revealed that Goko Cleanser contains some haemopoietic benefits, but inhibit appetite centres. Hence, this study recommends that further study be carried out on the effects of this herbal mixture on the brain so as to reveal the extent of its effect on the appetite centres.

scholarly journals Subchronic exposure to Kafura; its neurotoxic potentials in young adult female Wistar rats

Heliyon ◽  
2020 ◽  
Vol 6 (3) ◽  
pp. e03514
Author(s):  
Anoka A. Njan ◽  
Mary O. Ologe ◽  
Olufunke E. Olorundare ◽  
Saheed O. Afolabi ◽  
Benjamin C. Ejimkonye ◽  
...  
Keyword(s):  
Young Adult ◽  
Adult Female ◽  
Wistar Rats ◽  
Subchronic Exposure ◽  
Female Wistar Rats

Effect of imidacloprid on antioxidant status and histopathological changes in ovary and uterus of adult female wistar rats

2018 ◽  
Author(s):  
Archana Lohiya ◽  
Vinod Kumar ◽  
J.S. Punia
Keyword(s):  
Oxidative Stress ◽  
Adult Female ◽  
Wistar Rats ◽  
Control Programme ◽  
Female Rats ◽  
Histopathological Changes ◽  
Gum Acacia ◽  
Flea Control ◽  
Female Wistar Rats ◽  
Neonicotinoid Insecticide

Imidacloprid is a neonicotinoid insecticide and has been extensively used as a crop pest and in pet flea control programme. In the present study, the effects of imidacloprid on ovary and uteri tissue was analyzed in adult female Wistar rats at two dose levels (19 and 38 mg/kg/day) administered orally for 10, 20 and 30 days. Effects were compared with respective control animals administered daily with 2% gum acacia. Parameters undertaken were organ weight, levels of cytoplasmic and membrane proteins, oxidative stress parameters viz. activities of SOD, GPx and levels of GSH and MDA and histopathological changes. IMI (38 mg/kg, 30 days) reduced cytoplamic proteins in both ovaries and uteri whereas this dose reduced membrane protein in ovaries only. IMI (38 mg/kg, 20 and 30 days) decreased SOD enzyme in both ovaries and uteri and GSH-Px levels in ovaries only. The GSH-Px levels were also seen with decreased levels in uteri with IMI (38 mg/kg) for 30 days. IMI (38 mg/kg, 20 and 30 days) induces degenerative changes in ovaries of rats. Hence, it is concluded from the present studies that administration of higher doses (38 mg/kg/day) of IMI for 20 and 30 days generated oxidative stress in ovaries and uteri of female rats.

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