scholarly journals Endocrine disruption by PFAS: A major concern associated with legacy and replacement substances

2021 ◽  
Vol 71 (6) ◽  
pp. 429-454
Author(s):  
Emiliano Panieri ◽  
Aleksandra Buha-Đorđevic ◽  
Luciano Saso
Keyword(s):  
Weight Control ◽  
Environmental Fate ◽  
Endocrine System ◽  
Carbon Chain ◽  
Reproductive Capacity ◽  
Human Populations ◽  
Range Transport ◽  
Human Reproductive ◽  
Living Organisms ◽  
Body Weight Control

Perand poly-fluorinated alkyl substances (PFAS) have been used for decades in a great variety of processes and products by virtue of their exceptional properties, versatility and chemical stability. Nevertheless, it is increasingly recognized that these substances can represent a serious hazard to human health and living organisms due to their persistence, long-range transport potential and tendency to accumulate in biota. For this reason, some efforts have been made across the EU to identify alternative molecules, with a shorter carbon chain and theoretically safer profile, that might replace the previous generation of legacy PFAS. Unfortunately, this strategy has not been entirely successful and serious concerns are still posed by PFAS in different human populations. Among others, an emerging aspect is represented by the adverse effects that both legacy and alternative PFAS can exert on the human endocrine system, with respect to vulnerable target subpopulations. In this review we will briefly summarize PFAS properties, uses and environmental fate, focusing on their effects on human reproductive capacity and fertility, body weight control and obesity as well as thyroid function.

scholarly journals Az étrend szerepe a húgyúti kövek kialakulásában és megelőzésében

2017 ◽  
Vol 158 (22) ◽  
pp. 851-855 ◽  
Author(s):  
Attila Szendrői ◽  
Ákos Tordé ◽  
Judit Vargha ◽  
Gergely Bánfi ◽  
András Horváth ◽  
...  
Keyword(s):  
Weight Control ◽  
Fruits And Vegetables ◽  
Fluid Intake ◽  
Stone Formation ◽  
Family Doctor ◽  
Developed Countries ◽  
Urinary Stones ◽  
Nutritional Components ◽  
The Developed Countries ◽  
Body Weight Control

Abstract: In Hungary and in the developed countries urinary stones occur more often due to nutritional habits, obesity and sedentary lifestyle beside the endocrine and metabolic causes. In the daily urological and family doctor practice prevention should have an important role. Prevention is based not only on body weight control, physical exercise and medical treatment, but on proper diet as well. The nutritional components can change the consistence of urine, causing supersaturation, which is essential in stone formation. Specific nutritional components can either prevent stone formation (increased fluid intake, citrate, magnesium, fruits and vegetables) or either increase stone formation (decreased fluid intake, proteins, carbohydrates, oxalate, salt, increased calcium intake, ascorbic-acid etc). We summarized evidence-based practical dietary suggestions on the primary and secondary prevention of urinary stones. Orv Hetil. 2017; 158(22): 851–855.

Recent insights into body weight control: From physiology to pathology

2001 ◽  
Vol 7 (11) ◽  
pp. 571-578 ◽  
Author(s):  
Robert Krysiak ◽  
Bogus?aw Okopie? ◽  
Dariusz Belowski ◽  
Andrzej Madej ◽  
Zbigniew Stanis?aw Herman
Keyword(s):  
Body Weight ◽  
Weight Control ◽  
Body Weight Control

scholarly journals Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review

2021 ◽  
Vol 18 (13) ◽  
pp. 7170
Author(s):  
Helena Pinos ◽  
Beatriz Carrillo ◽  
Ana Merchán ◽  
Judit Biosca-Brull ◽  
Cristian Pérez-Fernández ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Weight ◽  
Weight Control ◽  
Animal Studies ◽  
Pesticide Exposure ◽  
Endocrine Disrupting Chemicals ◽  
Overweight And Obesity ◽  
Postnatal Exposure ◽  
Body Weight Control ◽  
The Impact

In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health.

scholarly journals Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control

2016 ◽  
Vol 23 (5) ◽  
pp. 797-810 ◽  
Author(s):  
Tina Djogo ◽  
Sarah C. Robins ◽  
Sarah Schneider ◽  
Darya Kryzskaya ◽  
Xiaohong Liu ◽  
...  
Keyword(s):  
Body Weight ◽  
Median Eminence ◽  
Weight Control ◽  
Body Weight Control

Disturbed Body Weight Control in Geriatric Rats: a Model for Anorexia in Alzheimers

1992 ◽  
pp. 451-459
Author(s):  
Collin R. Park ◽  
Sabine M. von Preyss-Friedman ◽  
Robert S. Schwartz ◽  
Stephen C. Woods
Keyword(s):  
Body Weight ◽  
Weight Control ◽  
Body Weight Control
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