scholarly journals Diagnosis of Oral Lichen Planus and Oral Leukoplakia using Contact Mucoscopy

2011 ◽  
Vol 17 (1) ◽  
pp. 7-16
Author(s):  
Hiroyuki SAKAMAKI ◽  
Yoko FUJIMOTO ◽  
Yoshito TAKEDA ◽  
Naomi OGURA ◽  
Tadahiko UTSUNOMIYA ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Oral Leukoplakia ◽  
Oral Lichen

scholarly journals Association of Human Papillomavirus With Oral Lichen Planus and Oral Leukoplakia: A Meta-analysis

2020 ◽  
Vol 20 (4) ◽  
pp. 101485
Author(s):  
Qianhui Shang ◽  
Jiakuan Peng ◽  
Yu Zhou ◽  
Qianming Chen ◽  
Hao Xu
Keyword(s):  
Human Papillomavirus ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Meta Analysis ◽  
Oral Leukoplakia ◽  
Oral Lichen

Assessment and Comparison of Salivary Survivin Biomarker in Oral Leukoplakia, Oral Lichen Planus, and Oral Cancer: A Comparative Study

2017 ◽  
Vol 8 (2) ◽  
pp. 73-76 ◽  
Author(s):  
Ruchika Garg ◽  
Arvind V Shetti ◽  
Anjana S Bagewadi
Keyword(s):  
Oral Cancer ◽  
Comparative Study ◽  
Malignant Transformation ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Oral Leukoplakia ◽  
Control Group ◽  
Significant Difference ◽  
Potentially Malignant ◽  
Oral Lichen

ABSTRACT Introduction Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral cavity. It is preceded by various potentially malignant conditions like oral leukoplakia and oral lichen planus. Survivin is an inhibitor of apoptosis whose levels have been found increased in oral cancer as well as various potentially malignant conditions. Thus survivin can act as a biomarker and help in early detection of potentially malignant conditions which can prevent its transformation into malignancy. Aim To assess and compare the level of total human salivary survivin in oral leukoplakia, oral lichen planus, oral cancer, and control group. Materials and methods A total of 96 subjects were included in the study, which were further grouped into 24 in each group. The saliva was analyzed for survivin level among all the four groups. Survivin concentration (pg/mL) was studied in relation to clinical data. The results were analyzed using Mann—Whitney U test to derive the statistical difference. Results The average of levels of survivin in control group was 0.199 pg/mL, in oral leukoplakia group 0.312 pg/mL, in oral lichen planus group 0.380 pg/mL, and in oral cancer group 0.430 pg/mL. A comparison of all these groups revealed statistically significant difference among the groups. Conclusion Survivin may not be considered as an independent predictor of the malignant transformation for premalignant lesions but it can be an indicator for an increased risk of malignant transformation. How to cite this article Garg R, Shetti AV, Bagewadi AS. Assessment and Comparison of Salivary Survivin Biomarker in Oral Leukoplakia, Oral Lichen Planus, and Oral Cancer: A Comparative Study. World J Dent 2017;8(2):73-76.

A metabonomic approach to the diagnosis of oral squamous cell carcinoma, oral lichen planus and oral leukoplakia

Oral Oncology ◽  
2008 ◽  
Vol 44 (5) ◽  
pp. 477-483 ◽  
Author(s):  
Shi-Kai Yan ◽  
Ben-Juan Wei ◽  
Zhong-Ying Lin ◽  
Yun Yang ◽  
Zeng-Tong Zhou ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Oral Lichen Planus ◽  
Oral Leukoplakia ◽  
Oral Lichen

scholarly journals Photodynamic therapy of oral leukoplakia and oral lichen planus using methylene blue: A pilot study

2015 ◽  
Vol 08 (01) ◽  
pp. 1540005 ◽  
Author(s):  
Savarimuthu Wilfred Prasanna ◽  
Ekta Ingle ◽  
Prakasa Rao Aruna ◽  
Chidambaranathan Pravada ◽  
Dornadula Koteeswaran ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Photodynamic Therapy ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Light Exposure ◽  
Oral Leukoplakia ◽  
Premalignant Lesions ◽  
Therapeutic Modality ◽  
Oral Lichen

Premalignant lesions like oral lichen planus (OLP), oral leukoplakia (OL) has a fair probability of transforming into malignancy and they are perverse toward conventional therapies. Photodynamic therapy (PDT) has been considered as an alternative/complimentary therapeutic modality for the management of premalignant lesions. In this study, methylene blue-mediated photodynamic therapy (MB-PDT) was used as a possible alternative method for the treatment of OLP and OL. A total of 15 OLP lesions and 13 OL lesions were enrolled in the study. The patients were irradiated using metal halide lamp filtered at 630 ± 10 nm, with a light exposure dose of 120 J/cm2 per sitting. For the OLP lesions, MB-PDT was performed once a week for four weeks and for the OL lesions, MB-PDT was performed twice a week for three weeks. Lesions were evaluated pre- and post- and at follow-up sessions by changes in sign and symptom scores, and size of lesions. We have observed a 53.3% of complete reduction in the treated OLP lesions and their decrease in size, sign and symptom score after treatment and at follow-up session was statistically significant. We have also observed complete response for one OL lesion of the 13 treated lesions. The result indicates that MB-PDT is an effective modality in management of OLP and OL. Among the two types of premalignancies treated with MB-PDT, OLP lesions responded much better than that of OL.

scholarly journals Prevention of Malignant Transformation of Oral Leukoplakia and Oral Lichen Planus Using Laser: An Observational Study

2018 ◽  
Vol 19 (12) ◽  
pp. 3635-3641 ◽  
Author(s):  
Karandeep Singh Arora ◽  
Rahul Bansal ◽  
Shreeyam Mohapatra ◽  
Akshay Verma ◽  
Sakshi Sharma ◽  
...  
Keyword(s):  
Observational Study ◽  
Malignant Transformation ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Oral Leukoplakia ◽  
Oral Lichen

Expression of survivin in oral leukoplakia and oral lichen planus

2021 ◽  
Author(s):  
Lalitha CHINTALA ◽  
Khaja A. HUSSAIN ◽  
Srikanth KODANGAL ◽  
Amara S. LINGAM ◽  
Raghunath DANTU ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Oral Leukoplakia ◽  
Oral Lichen

Galectin-9 as an important marker in the differential diagnosis between oral squamous cell carcinoma, oral leukoplakia and oral lichen planus

Immunobiology ◽  
2015 ◽  
Vol 220 (8) ◽  
pp. 1006-1011 ◽  
Author(s):  
Janusa Maria Muniz ◽  
Cláudia Renata Bibiano Borges ◽  
Marcela Beghini ◽  
Marcelo Sivieri de Araújo ◽  
Polyanna Miranda Alves ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Differential Diagnosis ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Oral Lichen Planus ◽  
Oral Leukoplakia ◽  
Oral Lichen ◽  
Important Marker
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