scholarly journals Peripheral oxygen saturation, heart rate, and blood pressure during dental treatment of children with cyanotic congenital heart disease

Clinics ◽  
2014 ◽  
Vol 69 (5) ◽  
pp. 314-318 ◽  
Author(s):  
RM Dutra ◽  
IL Neves ◽  
RS Neves ◽  
E Atik ◽  
UP Santos
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Oxygen Saturation ◽  
Congenital Heart ◽  
Dental Treatment ◽  
Cyanotic Congenital Heart Disease ◽  
Peripheral Oxygen Saturation

scholarly journals Low peripheral oxygen saturation as a risk factor for brain abscess in children with cyanotic congenital heart disease

2018 ◽  
Vol 58 (5) ◽  
pp. 252-6
Author(s):  
Nadia Qoriah Firdausy ◽  
Indah Kartika Murni ◽  
Agung Triono ◽  
Noormanto Noormanto ◽  
Sasmito Nugroho
Keyword(s):  
Congenital Heart Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Oxygen Saturation ◽  
Brain Abscess ◽  
Congenital Heart ◽  
Significant Risk ◽  
Cyanotic Congenital Heart Disease ◽  
Arterial Oxygen ◽  
Peripheral Oxygen Saturation

Background Brain abscess is a severe infection of brain parenchyma, which occurs in 25-46% of cases of uncorrected cyanotic congenital heart disease. Low arterial oxygen saturation is the main risk factor for brain abscess in children with cyanotic congenital heart disease, however, the arterial oxygen saturation test is invasive and not routinely done in our setting. Objective To evaluate low peripheral oxygen saturation as a risk factor for brain abscess in children with cyanotic congenital heart disease. Methods We conducted a matched, case-control study at Sardjito Hospital, Yogyakarta for children aged less than 18 years with cyanotic congenital heart disease, from 2010-2016. Case subjects were children with brain abscess complications. The control group had only cyanotic congenital heart disease, and were matched for age and sex to the case group. During hospitalization due to the brain abscess complication in the case group, data regarding peripheral oxygen saturation, polycythemia, pneumonia, sepsis, dental caries and restricted pulmonary blood flow were collected and compared between both groups. Results During the study period, 18 children with cyanotic congenital heart disease had brain abscesses. This group was compared to the control group of 36 children. Bivariate analysis revealed that the lowest level of peripheral oxygen saturation (OR 0.92; 95%CI 0.85 to 0.98; P=0.02) and dental caries (OR 3.3; 95%CI 1.01 to 11.18; P=0.04) were significant risk factors for brain abscess. However, in the multivariate analysis, the only statistically significant risk factor associated with brain abscess was the lowest level of peripheral oxygen saturation (OR 0.92; 95%CI 0.86 to 0.99; P=0.04). Conclusion Low peripheral oxygen saturation is a significant risk factor for brain abscess development in children with cyanotic congenital heart disease.  A decrease of 1% peripheral oxygen saturation may increase the risk of brain abscess by 8%.

scholarly journals Association between Objectively Measured Physical Activity and Arterial Stiffness in Children with Congenital Heart Disease

2021 ◽  
Vol 10 (15) ◽  
pp. 3266
Author(s):  
Laura Willinger ◽  
Leon Brudy ◽  
Renate Oberhoffer-Fritz ◽  
Peter Ewert ◽  
Jan Müller
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Heart Rate ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Arterial Stiffness ◽  
Systolic Blood Pressure ◽  
Congenital Heart ◽  
Z Score ◽  
Objectively Measured

Background: The association between physical activity (PA) and arterial stiffness is particularly important in children with congenital heart disease (CHD) who are at risk for arterial stiffening. The aim of this study was to examine the association between objectively measured PA and arterial stiffness in children and adolescents with CHD. Methods: In 387 children and adolescents with various CHD (12.2 ± 3.3 years; 162 girls) moderate-to-vigorous PA (MVPA) was assessed with the “Garmin vivofit jr.” for 7 consecutive days. Arterial stiffness parameters including pulse wave velocity (PWV) and central systolic blood pressure (cSBP) were non-invasively assessed by oscillometric measurement via Mobil-O-Graph®. Results: MVPA was not associated with PWV (ß = −0.025, p = 0.446) and cSBP (ß = −0.020, p = 0.552) in children with CHD after adjusting for age, sex, BMI z-score, peripheral systolic blood pressure, heart rate and hypertensive agents. Children with CHD were remarkably active with 80% of the study population reaching the WHO recommendation of average 60 min of MVPA per day. Arterial stiffness did not differ between low-active and high-active CHD group after adjusting for age, sex, BMI z-score, peripheral systolic blood pressure, heart rate and hypertensive agents (PWV: F = 0.530, p = 0.467; cSBP: F = 0.843, p = 0.359). Conclusion: In this active cohort, no association between PA and arterial stiffness was found. Longer exposure to the respective risk factors of physical inactivity might be necessary to determine an impact of PA on the vascular system.

Developmental Alterations of Cerebral Gray and White Matter in Children with Congenital Cyanotic Heart Disease

2018 ◽  
Vol 17 (05) ◽  
pp. 161-167
Author(s):  
Juan Leon-Wyss ◽  
Cynthia Rosario ◽  
Janet Toribio ◽  
Herwin Speckter ◽  
Bernd Foerster ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
White Matter ◽  
Oxygen Saturation ◽  
Congenital Heart ◽  
Diffusion Tensor ◽  
Cyanotic Congenital Heart Disease ◽  
Congenital Cyanotic Heart Disease ◽  
Diffusion Tensor Imaging Dti

AbstractThis article examines the relation between oxygen saturation and T2 star time in cyanotic congenital heart disease and its correlation to cerebral gray and white matter alterations. Magnetic resonance imaging was performed in 25 patients (mean age: 52.2 months) and 32 controls. Gray and white matter volumes, as well as fractional anisotropy and longitudinal diffusivity, were significantly reduced in patients. The reduction longitudinal diffusivity correlated to oxygen saturation and T2 star time of gray matter (p < 0.05). This diffusion tensor imaging (DTI) parameter was most affected in cyanotic congenital heart disease and because is the only parameter showing significant correlation to reduced oxygenation, it should be included more often in the follow-up of these patients over time.

Abstract 5716: Should We Treat Hyperuricemia in Adult Patients With Cyanotic Congenital Heart Disease?

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Hideshi Yamamura ◽  
Kei Inai ◽  
Tokuko Shinohara ◽  
Hirofumi Tomimatsu ◽  
Yoshiki Mori ◽  
...  
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Serum Creatinine ◽  
Oxygen Saturation ◽  
Congenital Heart ◽  
Gouty Arthritis ◽  
Cyanotic Congenital Heart Disease ◽  
Adult Patients ◽  
List Type

Background: Although hyperuricemia is common, it is thought that gouty arthritis is rare in adult patients (pts) with cyanotic congenital heart disease (CCHD). However, the actual frequency of hyperuricemia and gout has not been documented. Furthermore, whether hyperuricemia should be treated remains undetermined. This study investigated the incidence of hyperuricemia and gout, risk factors for hyperuricemia and gout, and whether the use of allopurinol decreases the incidence of gout in adult patients with CCHD. Methods: We studied 92 pts with CCHD, including 19 pts with Eisenmenger syndrome (mean age: 33±11 years of age, ranging from 15 to 61), M/F = 48/44) (CCHD group). Comparative data was obtained from 210 acyanotic CHD pts after biventricular repair (mean age: 31±11 years, ranging from 15 to 83, M/F = 98/112) (ACHD group). Hyperuricemia was defined as serum uric acid (UA) > 7.0mg/dl. The risk factors studied were: age, gender, RBC counts, hemoglobin, hematocrit, oxygen saturation, serum creatinine, glomerular filtration rate, cardiothoracic ratio, brain natriuretic peptide and medications, including diuretics, beta-blocker and aspirin. Results: Prevalence of hyperuricemia was 76% in the CCHD group and 24% in the ACHD group. Logistic regression analysis demonstrated that variables that significantly influence hyperuricemia were; hemoglobin over 18g/dl (odds ratio 6.2), oxygen saturation less than 90 (OR 4.8), the use of diuretics (OR 4.0), and serum creatinine higher than 1.0 mg/dl (OR 2.0). Gouty arthritis was observed in 16% in the CCHD group and only 1% in the ACHD group. The prevalence of hyperuricemia and gout in the CCHD group was significantly higher than that in the ACHD group. Of 92 pts in the CCHD group, allopurinol was administered to 37 pts for gout prophylaxis. Of 55 pts without allopurinol, 13 (24%) suffered from gout. In contrast, only 2 of 37 pts (5%) on allopurinol developed gout and the incidence was significantly lower than that in pts without allopurinol. Conclusion: These data suggest that in adult patients with CCHD, the incidence of gout is high, desaturation, polycytemia, impaired renal function, and the use of diuretics are risk factors for hyperuricemia and gout, and hyperuricemia should be treated with medication.

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