Classification of Urban Regeneration Activation Areas by the Levels of the Population Extinction Risk - A Case Study of Gyeongsangbuk-do -

2021 ◽  
Vol 32 (3) ◽  
pp. 165-172
Author(s):  
Seong-Ho Lim ◽  
Han-Soo Kim
Keyword(s):  
Extinction Risk ◽  
Urban Regeneration ◽  
Population Extinction

scholarly journals Assessment of health/functioning of older adults who consume psychoactive substances

2018 ◽  
Vol 71 (3) ◽  
pp. 942-950
Author(s):  
Vania Dias Cruz ◽  
Silvana Sidney Costa Santos ◽  
Jamila Geri Tomaschewski-Barlem ◽  
Bárbara Tarouco da Silva ◽  
Celmira Lange ◽  
...  
Keyword(s):  
Older Adults ◽  
Qualitative Case Study ◽  
International Classification Of Functioning ◽  
Psychoactive Substances ◽  
Systematic Observation ◽  
Health Functioning ◽  
Final Consideration ◽  
Theory Of Complexity

ABSTRACT Objective: To assess the health/functioning of the older adult who consumes psychoactive substances through the International Classification of Functioning, Disability and Health, considering the theory of complexity. Method: Qualitative case study, with 11 older adults, held between December 2015 and February 2016 in the state of Rio Grande do Sul, using interviews, documents and non-systematic observation. It was approved by the ethics committee. The analysis followed the propositions of the case study, using the complexity of Morin as theoretical basis. Results: We identified older adults who consider themselves healthy and show alterations - the alterations can be exacerbated by the use of psychoactive substances - of health/functioning expected according to the natural course of aging such as: systemic arterial hypertension; depressive symptoms; dizziness; tinnitus; harmed sleep/rest; and inadequate food and water consumption. Final consideration: The assessment of health/functioning of older adults who use psychoactive substances, guided by complex thinking, exceeds the accuracy limits to risk the understanding of the phenomena in its complexity.

scholarly journals Non financial compensation for the redevelopment of the historic urban landscape: the case study of Villasor in Sardinia (Italy)

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Anna Maria Colavitti ◽  
Sergio Serra
Keyword(s):  
Planning Process ◽  
Urban Landscape ◽  
Public Funding ◽  
Urban Regeneration ◽  
Conservation Strategies ◽  
Urban Fabric ◽  
Financial Compensation ◽  
Contemporary World ◽  
Italian Experience

Abstract In Europe, the debate on the recovery of the historic centres has been developed, over the years, around the balance between conservation and transformation needs in order to meet the new demands of the contemporary world. In the field of urban planning, the strictly conservative and binding approach has gradually been supported by flexible and consensual mechanisms that act as a stimulus to private initiative in the redevelopment and regeneration of the historic urban landscape. The consolidated Italian experience in the policies for the protection and enhancement of historical settlements is being significantly innovated after the entry into force of the Urbani Code, which extends the character of landscape heritage to the historic urban fabric, transferring to the regional authorities the task of establishing the specific regulations for its use and transformation. The Region of Sardinia has achieved an important role in the implementation of policies for the recovery and redevelopment of the historic centres identified by the Regional Landscape Plan (RLP). The common and consolidated practice is still characterized by the use of traditional regulative instruments, in particular the detailed plan, which provide rules for the requalification of the compromised urban fabrics through a set of rules and guidelines to be applied to the replacement of recent buildings and the renovation of urban patterns that for density, ratios between solids and voids, heights, alignments and elevations are incompatible with the values of the context. The constraint and binding approach is effective in the conservation strategies but often inadequate to implement actions of integrated redevelopment of urban fabric altered by new buildings in contrast with the historic urban landscape features, also due to the global crisis situation and the shortage of public funding. The paper proposes the use of the non-financial compensation tool, based on the granting of bonus development rights to realising on site or in alternative locations, in order to encourage urban regeneration projects that also involve the replacement of buildings incompatible with historical urban landscape morphological patterns. The integration of a methodology for assessing the financial feasibility of the demolition and reconstruction of the incompatible structures in the planning process, as tested in the case study of Villasor municipality, has allowed the elaboration of a model to support the use of a compensation mechanism for the redevelopment of historical settlement values. In this perspective, the paper aims to investigate the opportunities provided by market-oriented and flexible approaches to support and promote private urban regeneration projects. In particular, it illustrates the experimental results of a methodology for the analysis of the urban fabric that takes into account the factors influencing the feasibility of the intervention of demolition and reconstruction of the incompatible buildings. Finally a model for the assessment of any bonus in terms of additional building capacity is suggested, to be granted to private operators as an incentive to ensure the cost-effectiveness of the project.

scholarly journals Sparse Autoencoder-based Multi-head Deep Neural Networks for Machinery Fault Diagnostics with Detection of Novelties

2021 ◽  
Vol 34 (1) ◽  
Author(s):  
Zhe Yang ◽  
Dejan Gjorgjevikj ◽  
Jianyu Long ◽  
Yanyang Zi ◽  
Shaohui Zhang ◽  
...  
Keyword(s):  
Fault Diagnosis ◽  
Supervised Classification ◽  
Deep Neural Networks ◽  
Activation Function ◽  
Reconstruction Error ◽  
Fine Tuning ◽  
Fault Diagnostics ◽  
Sparse Autoencoder

AbstractSupervised fault diagnosis typically assumes that all the types of machinery failures are known. However, in practice unknown types of defect, i.e., novelties, may occur, whose detection is a challenging task. In this paper, a novel fault diagnostic method is developed for both diagnostics and detection of novelties. To this end, a sparse autoencoder-based multi-head Deep Neural Network (DNN) is presented to jointly learn a shared encoding representation for both unsupervised reconstruction and supervised classification of the monitoring data. The detection of novelties is based on the reconstruction error. Moreover, the computational burden is reduced by directly training the multi-head DNN with rectified linear unit activation function, instead of performing the pre-training and fine-tuning phases required for classical DNNs. The addressed method is applied to a benchmark bearing case study and to experimental data acquired from a delta 3D printer. The results show that its performance is satisfactory both in detection of novelties and fault diagnosis, outperforming other state-of-the-art methods. This research proposes a novel fault diagnostics method which can not only diagnose the known type of defect, but also detect unknown types of defects.

scholarly journals Neither a Novel Tau Proteinopathy nor an Expansion of a Phenotype: Reappraising Clinicopathology-Based Nosology

2021 ◽  
Vol 22 (14) ◽  
pp. 7292
Author(s):  
Luca Marsili ◽  
Jennifer Sharma ◽  
Alberto J. Espay ◽  
Alice Migazzi ◽  
Elhusseini Abdelghany ◽  
...  
Keyword(s):  
Spinocerebellar Ataxia Type ◽  
Niemann Pick Disease ◽  
Whole Exome ◽  
Heterozygous Variant ◽  
History Of ◽  
Ataxia Syndrome ◽  
Niemann Pick

The gold standard for classification of neurodegenerative diseases is postmortem histopathology; however, the diagnostic odyssey of this case challenges such a clinicopathologic model. We evaluated a 60-year-old woman with a 7-year history of a progressive dystonia–ataxia syndrome with supranuclear gaze palsy, suspected to represent Niemann–Pick disease Type C. Postmortem evaluation unexpectedly demonstrated neurodegeneration with 4-repeat tau deposition in a distribution diagnostic of progressive supranuclear palsy (PSP). Whole-exome sequencing revealed a new heterozygous variant in TGM6, associated with spinocerebellar ataxia type 35 (SCA35). This novel TGM6 variant reduced transglutaminase activity in vitro, suggesting it was pathogenic. This case could be interpreted as expanding: (1) the PSP phenotype to include a spinocerebellar variant; (2) SCA35 as a tau proteinopathy; or (3) TGM6 as a novel genetic variant underlying a SCA35 phenotype with PSP pathology. None of these interpretations seem adequate. We instead hypothesize that impairment in the crosslinking of tau by the TGM6-encoded transglutaminase enzyme may compromise tau functionally and structurally, leading to its aggregation in a pattern currently classified as PSP. The lessons from this case study encourage a reassessment of our clinicopathology-based nosology.

Sign in / Sign up

Export Citation Format

Share Document