Targeting TPX2 Suppresses the Tumorigenesis of Hepatocellular Carcinoma Cells Resulting in Arrested Mitotic Phase Progression and Increased Genomic Instability

Chao-Wen Hsu; Yu-Chia Chen; Hsing-Hao Su; Guan-Jin Huang; Chih-Wen Shu; Tony Tong-Lin Wu; Hung-Wei Pan

doi:10.7150/jca.17478

Targeting TPX2 Suppresses the Tumorigenesis of Hepatocellular Carcinoma Cells Resulting in Arrested Mitotic Phase Progression and Increased Genomic Instability

Journal of Cancer ◽

10.7150/jca.17478 ◽

2017 ◽

Vol 8 (8) ◽

pp. 1378-1394 ◽

Cited By ~ 18

Author(s):

Chao-Wen Hsu ◽

Yu-Chia Chen ◽

Hsing-Hao Su ◽

Guan-Jin Huang ◽

Chih-Wen Shu ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Genomic Instability ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Phase Progression

Interferon-α delays S-phase progression in human hepatocellular carcinoma cells via inhibition of specific cyclin-dependent kinases

Hepatology ◽

10.1053/jhep.2001.21749 ◽

2001 ◽

Vol 33 (2) ◽

pp. 346-356 ◽

Cited By ~ 56

Author(s):

D Murphy

Keyword(s):

Hepatocellular Carcinoma ◽

S Phase ◽

Carcinoma Cells ◽

Human Hepatocellular Carcinoma ◽

Interferon Α ◽

Hepatocellular Carcinoma Cells ◽

Cyclin Dependent Kinases ◽

Phase Progression ◽

Human Hepatocellular Carcinoma Cells

Quantitative Proteomics Reveals That the Inhibition of Na+/K+-ATPase Activity Affects S-Phase Progression Leading to a Chromosome Segregation Disorder by Attenuating the Aurora A Function in Hepatocellular Carcinoma Cells

Journal of Proteome Research ◽

10.1021/acs.jproteome.5b00724 ◽

2015 ◽

Vol 14 (11) ◽

pp. 4594-4602 ◽

Cited By ~ 11

Author(s):

Zhongwei Xu ◽

Fengmei Wang ◽

Fengxu Fan ◽

Yanjun Gu ◽

Nana Shan ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Atpase Activity ◽

Chromosome Segregation ◽

Quantitative Proteomics ◽

S Phase ◽

Carcinoma Cells ◽

Aurora A ◽

Hepatocellular Carcinoma Cells ◽

Phase Progression

The role of α2, αv and β1 Integrins in cell growth of hepatocellular carcinoma cells in vitro

Zeitschrift für Gastroenterologie ◽

10.1055/s-0037-1612833 ◽

2018 ◽

Vol 56 (01) ◽

pp. E2-E89

Author(s):

M Juratli ◽

A Schnitzbauer ◽

R Blaheta ◽

W Bechstein

Keyword(s):

Hepatocellular Carcinoma ◽

Cell Growth ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Β1 Integrins

Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MRP2 antisense constructs

Zeitschrift für Gastroenterologie ◽

10.1055/s-2004-816111 ◽

2004 ◽

Vol 42 (01) ◽

Author(s):

P Hafkemeyer ◽

Y Folmer ◽

C Fulda ◽

H Blum

Keyword(s):

Hepatocellular Carcinoma ◽

Drug Resistance ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Adenoviral Delivery ◽

Antisense Constructs

HGF/SF downstream signaling in human hepatoblastoma and hepatocellular carcinoma cells

Klinische Pädiatrie ◽

10.1055/s-2004-828568 ◽

2004 ◽

Vol 216 (03) ◽

Author(s):

S Grotegut ◽

E Fasler-Kan ◽

G Christofori ◽

D von Schweinitz

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Downstream Signaling

Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels

Forum on Immunopathological Diseases and Therapeutics ◽

10.1615/forumimmundisther.v2.i2.40 ◽

2011 ◽

Vol 2 (2) ◽

pp. 127-135 ◽

Cited By ~ 2

Author(s):

Luigi Inguglia ◽

Monica Notarbartolo ◽

Paola Poma ◽

Manuela Labbozzetta ◽

Natale D'Alessandro

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Molecular Analysis ◽

Histone Deacetylase Inhibitor ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Induction Of Apoptosis

Apoptotic Effect of Extract from Medicinal Mushroom from Taiwan Taiwanofungus salmoneus (Higher Basidiomycetes) Mycelium Combined with or without Cisplatin on Hepatocellular Carcinoma Cells

International Journal of Medicinal Mushrooms ◽

10.1615/intjmedmushrooms.v17.i6.70 ◽

2015 ◽

Vol 17 (6) ◽

pp. 567-577 ◽

Cited By ~ 2

Author(s):

Rao-Chi Chien ◽

Yun-Jung Hsieh ◽

Jeng-Leun Mau

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Medicinal Mushroom ◽

Hepatocellular Carcinoma Cells ◽

Apoptotic Effect

Effects of Liver Cancer Drugs on Cellular Energy Metabolism in Hepatocellular Carcinoma Cells

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2018.10.03.079 ◽

2018 ◽

Vol 10 (03) ◽

Keyword(s):

Hepatocellular Carcinoma ◽

Energy Metabolism ◽

Liver Cancer ◽

Carcinoma Cells ◽

Cancer Drugs ◽

Hepatocellular Carcinoma Cells ◽

Cellular Energy ◽

Cellular Energy Metabolism

Faculty Opinions recommendation of Loss of p53 and Ink4a/Arf cooperate in a cell autonomous fashion to induce metastasis of hepatocellular carcinoma cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1090889.544239 ◽

2007 ◽

Author(s):

Shannon Glaser

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

A Cell

Faculty Opinions recommendation of Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5261961.5217056 ◽

2010 ◽

Author(s):

Grace Guo ◽

Guodong Li

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Tumor Growth ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Growth Factor Beta