scholarly journals Novel evidence of obesity paradox in esophageal adenocarcinoma: perspective on genes that uncouple adiposity from dismal outcomes

2022 ◽  
Vol 13 (2) ◽  
pp. 436-449
Author(s):  
Lei Zhu ◽  
Fugui Yang ◽  
Lin Dong ◽  
Guangxue Wang ◽  
Qinchuan Li ◽  
...  
Keyword(s):  
Esophageal Adenocarcinoma ◽  
Obesity Paradox

On the origin of the rising incidence of esophageal adenocarcinoma and prediction of future trends

2001 ◽  
Vol 120 (5) ◽  
pp. A30-A30
Author(s):  
J HELM ◽  
J BARTHEL ◽  
D COPPOLA ◽  
P LAZARUS ◽  
S LUTHER ◽  
...  
Keyword(s):  
Esophageal Adenocarcinoma ◽  
Future Trends ◽  
Rising Incidence

Risk factors for esophageal adenocarcinoma: A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A442-A442
Author(s):  
B AVIDAN ◽  
A SONNENBERG ◽  
T SCHNELL ◽  
G CHEJFEC ◽  
A METZ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Adenocarcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Obesity Paradox Identified in Non-ST-Elevation MI

2005 ◽  
Vol 38 (5) ◽  
pp. 56
Author(s):  
BRUCE JANCIN
Keyword(s):  
Obesity Paradox ◽  
St Elevation

The Curious Rise of Esophageal Adenocarcinoma

2006 ◽  
Author(s):  
Carmen Phillips
Keyword(s):  
Esophageal Adenocarcinoma

FEASIBILITY OF SENTINEL NODE NAVIGATED SURGERY IN PATIENTS WITH HIGH-RISK SUBMUCOSAL (T1B) ESOPHAGEAL ADENOCARCINOMA USING A HYBRID TRACER OF TECHNETIUM-99M AND INDOCYANINE GREEN

2020 ◽  
Author(s):  
A Overwater ◽  
BLAM Weusten ◽  
JP Ruurda ◽  
R van Hillegersberg ◽  
RJ Bennink ◽  
...  
Keyword(s):  
High Risk ◽  
Indocyanine Green ◽  
Sentinel Node ◽  
Esophageal Adenocarcinoma ◽  
Technetium 99M ◽  
Navigated Surgery ◽  
Hybrid Tracer

Short Tandem Repeat Polymorphisms in Esophageal Cancer Related Gene –2 are a Risk Faktor for Esophageal Adenocarcinoma

2005 ◽  
Vol 43 (05) ◽  
Author(s):  
T Rawnaq ◽  
JT Kaifi ◽  
EF Yekebas ◽  
R Wachowiak ◽  
M Bubenheim ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Esophageal Adenocarcinoma ◽  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Related Gene ◽  
Cancer Related Gene ◽  
Short Tandem

BMI, mortality, and cardiovascular outcomes in type 1 diabetes: Findings against an obesity paradox

2019 ◽  
Author(s):  
Edqvist J ◽  
Rawshani A ◽  
Adiels M ◽  
Bjorck L ◽  
Lind M ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Obesity Paradox ◽  
Cardiovascular Outcomes

Esophageal Adenocarcinoma with Enteroblastic Differentiation Arising in Ectopic Gastric Mucosa in the Cervical Esophagus: a Case Report and Literature Review

2017 ◽  
Vol 26 (2) ◽  
pp. 193-197 ◽  
Author(s):  
Ryosuke Gushima ◽  
Rei Narita ◽  
Takashi Shono ◽  
Hideaki Naoe ◽  
Takashi Yao ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Esophageal Adenocarcinoma ◽  
Histopathological Examination ◽  
Narrow Band Imaging ◽  
Carbohydrate Antigen ◽  
Endoscopic Examination ◽  
Ectopic Gastric Mucosa ◽  
Tubular Adenocarcinoma ◽  
Positron Emission ◽  
Elevated Lesion

Background: Adenocarcinoma with enteroblastic differentiation is a subtype of alpha-fetoprotein (AFP) producing adenocarcinoma. This type of tumor is associated with a poor prognosis and is prone to metastasize. Esophageal adenocarcinoma with enteroblastic differentiation is extremely rare.Case presentation: The patient was a 65-year-old woman who was referred to our hospital with dysphagia. Endoscopic examination revealed an elevated lesion 20mm in diameter at 17cm from the upper incisors. Endoscopic submucosa dissection (ESD) was performed and histopathological examination revealed tubular adenocarcinoma composed of cuboidal cells with clear cell cytoplasm. Immunohistochemical stain was diffusely positive for Sall-like protein 4 (SALL4) and weakly positive for AFP and glypican 3. From this result, we diagnosed esophageal adenocarcinoma with enteroblastic differentiation. The patient is still alive without recurrence of cancer 40 months after ESD.Conclusion: To our knowledge, this is the first report to undergo ESD for esophageal adenocarcinoma with enteroblastic differentiation arising from ectopic gastric mucosa in the esophagus.Abbreviations: AFP: alfa-fetoprotein; CA19-9: carbohydrate antigen 19-9; CEA: carcinoembryonic antigen; ESD: endoscopic submucosal dissection; EUS: endoscopic ultrasound; FDG-PET: [18F] fluorodeoxyglucose positron emission tomography; ME: magnifying endoscopy; NBI: narrow band imaging; SALL 4: Sall-like protein 4; SCC: squamous cell carcinoma antigen.

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