scholarly journals Ozone Therapy as treatment for severe cases without good evolution in ophthalmology [abstract]

2019 ◽  
Vol 3 (4) ◽  
Author(s):  
Karla Tratsk

PURPOSE: In ophthalmology many diseases lead to irreversible blindness, something that implies millions of dollars in care because people with these difficulties loose their autonomy, becoming dependent in all their everyday activities. This presentation will focus on clinical cases of the following pathologies treated with Ozone Therapy because all these were already being treated in a conventional way without signs of improvement. They are primary open-angle glaucoma, age-related macular degeneration, diabetic retinopathy, occlusion of the central retinal artery, facial paralysis and herpetic polyneuropathy associated with orbital apex syndrome. CASE PRESENTATION: As an example, a patient, 73 , female, insulin-dependent diabetes for 10 years, with primary open angle glaucoma, diabetic retinopathy with various laser photocoagulations, vitrectomies and intravitreal injections in both eyes (BE). Visual acuity (VA) of 20/200 in right eye (RE) and 20/100 in left eye (LE). Subjected to the facectomy in RE and with cataract in LE. The fundoscopy was stable in BE. The VA went to 20/200 on 1st day of postoperative period and remained stable until 21st day. After integrative treatment with Ozone Therapy the patient got a VA of 20/60-2 in RE and 20/40-2 in LE, restoring vision and improving her quality of life. Furthermore, she stopped to be insulin dependent, only having to take oral medication. CONCLUSION: The result shows that Ozone therapy should be a therapeutic tool to be associated with Ophthalmology because in many cases, including difficult treatment and evolution, it recovers visual acuity and re-establishes ocular physiology, promoting the maintenance of eye health and vision, contributing to the preservation of autonomy in the lives of patients.

2021 ◽  
Vol 77 (3) ◽  
pp. 37-46
Author(s):  
K. A. Gudzenko ◽  
S. Yu. Mogilevskyy ◽  
М. L. Kyryliuk ◽  
D. S. Ziablitsev

The aim of this work was to identify risk factors for the occurrence of primary open-angle glaucoma in patients with diabetic retinopathy and type 2 diabetes mellitus by conducting a regression analysis of the mutual influence of these diseases. We examined 649 patients (649 eyes), among whom 301 patients (301 eyes) had diabetic retinopathy and glaucoma; 164 patients (164 eyes) had diabetic retinopathy only; 81 patients (81 eyes) had only glaucoma and 103 patients (103 eyes) did not have these diseases (control). The construction of logistic regression models was carried out in the GLZ module of the Statistica 10 software (StatSoft, Inc. USA). It was found that the development of primary open-angle glaucoma directly depended on the duration of diabetes and the intraocular pressure level, and vice versa — on visual acuity (p < 0.001). The development of diabetic retinopathy did not depend on the presence of glaucoma, but it was directly dependent on the blood content of glucose and glycated hemoglobin. Men had a lower risk of developing diabetic retinopathy than women(OR = 0.800; 95% CI 0.76-0.84). Also, men had a lower risk of glaucoma (OR = 0.95; 95% CI 0.94–0.96). Stratification by stages of diabetic retinopathy showed the effect of intraocular pressure, decreased visual acuity and glaucoma stages on the development of proliferative diabetic retinopathy (p < 0.001). Increased intraocular pressure was an independent factor in the development of retinopathy. The development of glaucoma of the initial stage was directly influenced by an increase of blood glycated hemoglobin and by the stage of diabetic retinopathy. The occurrence of stage 2 glaucoma was influenced by the duration of diabetes and visual acuity, stage 3 glaucoma — by visual acuity, and stage 4 glaucoma – by the age and duration of diabetes. Independent risk factors for glaucoma were duration of diabetes, increased intraocular pressure, and low visual acuity. When stratified by stage, there was no evidence of a reduction in the risk of developing diabetic retinopathy and glaucoma in men. Thus, the features of the mutual influence of the development of diabetic retinopathy and primary open-angle glaucoma in type 2 diabetes mellitus have been established.


2014 ◽  
Vol 7 (1) ◽  
pp. 19-27 ◽  
Author(s):  
R. V. Avdeyev ◽  
A. S. Aleksandrov ◽  
A. S. Basinskiy ◽  
Ye. A. Blyum ◽  
A. Yu. Brezhnev ◽  
...  

A study of cross-impact degree and morpho-functional correlation characteristics of primary open angle glaucoma and age-related macular degeneration was performed at 25 clinical sites in Russia and some CIS countries from January through May 2013. The study final protocol included 87 patients (108 eyes) divided into two groups, mean age of patients was 66.6 ± 5.65 years (min 55; max 81). Intragroup and intergroup variance analysis did not establish any significant difference in the macular area between the «glaucoma» group and the «glaucoma + AMD» group depending on the disease stage. The findings suggest that macular degeneration develops subsequent to a preexisting glaucomatous state.


2021 ◽  
Vol 2 (3) ◽  
pp. 5-10
Author(s):  
Saida Egamberdiyeva ◽  
◽  
Sarvarkhon Yuldashov ◽  
Azamjon Korabaev ◽  
Namunahon Askarova

Age-related macular degeneration (AMD) is a progressive eye disease in which the physiological function of the choriocapillaries, Bruch’s membrane, and retinal pigment epithelium (RPE) areimpaired, a defect in the photoreceptor layer occurs, and central vision is irreversible. Primary open-angle glaucoma (POAG)is a pathological process characterized by impaired hydrodynamicsof intraocular fluid and damage to the optic nerve, althoughthe anterior chamber angle is open. In this disease, intraocular pressure (IOP) often increases and peripheral vision decreases depending on the retinallayer's level of compression. According to WHO statistics, POAG is then complicated by the “dry” form of AMD in 41% of cases, i.e. an effectivecombination of the above two pathologies can be observed in clinical practice. Consumption of foods rich in antioxidant micronutrients and drugslikes“Ophthalmocomplex” in the prevention and treatment of chronic degenerative eye diseases such as primary open-angle glaucoma (POAG) and age-related macular degeneration (AMD) can shorten the rehabilitation period. Themechanisms of development of pathologicalprocesses (especially inflammation, degeneration) are different. Still,the main pathogenetic point is the disruption of the antioxidant defense system as a result of detoxification.Keywords: age-related macular degeneration (AMD), primary open-angle glaucoma (POAG), vitamins, antioxidants, partially oxidized free radicals, Ophthalmocomplex drug, healthy eating


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