scholarly journals De cigalas y humanos. Perspectiva evolucionista de la adicción

2021 ◽  
Author(s):  
Carmen Ferrer-Pérez ◽  
José Miñarro López
Keyword(s):  
Complex Disease ◽  
Drugs Of Abuse ◽  
Reward System ◽  
Holistic View ◽  
Biopsychosocial Approach ◽  
Behavioural Effects ◽  
The Brain

Addiction is a complex disease whose manifestation is unique to each individual patient. Despite this, our knowledge suggests that many of the consequences of using drugs of abuse are due to alterations in the brain, which would be similar from one individual to another. Specifically, abuse drugs act on the brain’s reward system to trigger behavioural effects. In this paper, we will unravel the functions and phylogenetic roots of this system and then explain how drugs of abuse can affect the functioning of the brain. Addiction research and treatment requires a biopsychosocial approach and hence, being aware of the phylogenetic side of this problem can help to build a holistic view of the disease.

Art and the Brain’s Reward System

2018 ◽  
Author(s):  
Henrik Hogh-Olesen
Keyword(s):  
Human Brain ◽  
Reward System ◽  
Human Existence ◽  
Brain Scans ◽  
System P ◽  
The Aesthetic ◽  
The Brain ◽  
Reward Circuit

Chapter 7 takes the investigation of the aesthetic impulse into the human brain to understand, first, why only we—and not our closest relatives among the primates—express ourselves aesthetically; and second, how the brain reacts when presented with aesthetic material. Brain scans are less useful when you are interested in the Why of aesthetic behavior rather than the How. Nevertheless, some brain studies have been ground-breaking, and neuroaesthetics offers a pivotal argument for the key function of the aesthetic impulse in human lives; it shows us that the brain’s reward circuit is activated when we are presented with aesthetic objects and stimuli. For why reward a perception or an activity that is evolutionarily useless and worthless in relation to human existence?

scholarly journals Learning of food preferences: mechanisms and implications for obesity & metabolic diseases

2021 ◽  
Author(s):  
Hans-Rudolf Berthoud ◽  
Christopher D. Morrison ◽  
Karen Ackroff ◽  
Anthony Sclafani
Keyword(s):  
Metabolic Diseases ◽  
Food Preferences ◽  
Reward System ◽  
Nutrient Sensing ◽  
Vagal Afferents ◽  
Dietary Knowledge ◽  
Ongoing Work ◽  
Brain Reward ◽  
The Brain ◽  
Vagal Function

AbstractOmnivores, including rodents and humans, compose their diets from a wide variety of potential foods. Beyond the guidance of a few basic orosensory biases such as attraction to sweet and avoidance of bitter, they have limited innate dietary knowledge and must learn to prefer foods based on their flavors and postoral effects. This review focuses on postoral nutrient sensing and signaling as an essential part of the reward system that shapes preferences for the associated flavors of foods. We discuss the extensive array of sensors in the gastrointestinal system and the vagal pathways conveying information about ingested nutrients to the brain. Earlier studies of vagal contributions were limited by nonselective methods that could not easily distinguish the contributions of subsets of vagal afferents. Recent advances in technique have generated substantial new details on sugar- and fat-responsive signaling pathways. We explain methods for conditioning flavor preferences and their use in evaluating gut–brain communication. The SGLT1 intestinal sugar sensor is important in sugar conditioning; the critical sensors for fat are less certain, though GPR40 and 120 fatty acid sensors have been implicated. Ongoing work points to particular vagal pathways to brain reward areas. An implication for obesity treatment is that bariatric surgery may alter vagal function.

scholarly journals How Intelligence is Understood Today

2021 ◽  
Vol 16 (3) ◽  
pp. 0
Author(s):  
Rustam Khasanov
Keyword(s):  
Animal Behavior ◽  
Learning Algorithms ◽  
Cognitive Activity ◽  
Reward System ◽  
Assessment System ◽  
New Developments ◽  
Intellectual Abilities ◽  
Complex Adaptive ◽  
The Brain ◽  
Adaptive Abilities

The article is devoted to understanding the ways of explaining intellectual abilities in the light of new developments in the field of artificial intelligence and discoveries related to the study of complex adaptive animal behavior based on the reward system. The paper reviews the latest advances in the development of biologically plausible learning algorithms, the purpose of which is to explain the large amount of accumulated data from the field of neuroscience. Within the framework of this approach, reinforcement learning algorithms are proposed as the basis for any kind of cognitive activity. Understanding intelligence as a set of flexible adaptive abilities to achieve a goal provides a new conceptual framework for explaining how the brain works at a functional level. The formation of forecasts for the future, the construction of time steps and the existence of an internal assessment system in such systems is psychologically and biologically plausible and can potentially become a new milestone in the study of intelligence.

Have Sexual Pheromones Their Own Reward System in the Brain of Female Mice?

2007 ◽  
pp. 261-270 ◽  
Author(s):  
Fernando Martínez-García ◽  
Carmen Agustín-Pavón ◽  
Jose Martínez-Hernández ◽  
Joana Martínez-Ricós ◽  
Jose Moncho-Bogani ◽  
...  
Keyword(s):  
Reward System ◽  
Female Mice ◽  
Sexual Pheromones ◽  
The Brain

Mental and behavioural disorders

2020 ◽  
pp. 333-365
Author(s):  
Fabrizio Benedetti
Keyword(s):  
Clinical Trials ◽  
Mental Disorders ◽  
Placebo Effect ◽  
Crucial Role ◽  
Drugs Of Abuse ◽  
Placebo Treatment ◽  
Brain Regions ◽  
Psychotherapeutic Interventions ◽  
Psychotherapeutic Outcome ◽  
The Brain

In this chapter some mental disorders are described. For example, in depression, fluoxetine treatment and a placebo treatment affect similar brain regions. In anxiety, patients’ expectations play a crucial role, as covert (unexpected) administration of anti-anxiety drugs is less effective than overt (expected) administration. The disruption of prefrontal executive control in Alzheimer’s disease decreases the magnitude of placebo responses. In addition, expectations appear to be particularly important when associated with the effects of drugs of abuse. Placebo effects appear to be powerful in psychotherapy as well, and the brain areas involved in the psychotherapeutic outcome are different from those involved in the placebo effect. As clinical trials for psychotherapeutic interventions represent a major problem, new recommendations are presented.

Neurochemical Systems in the Central Nervous System

2013 ◽  
pp. 12-26
Author(s):  
Ariel Y. Deutch ◽  
Robert H. Roth
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Psychiatric Disorders ◽  
Neurotrophic Factors ◽  
Drugs Of Abuse ◽  
Large Majority ◽  
System P ◽  
Target Neuron ◽  
The Central Nervous System ◽  
The Brain

Chapter 2 describes the neurochemical organization of the brain. It summarizes the diverse types of molecules that neurons in the brain use as neurotransmitters and neurotrophic factors, and how these molecules are synthesized and metabolized. The chapter also presents the array of receptor proteins through which these molecules regulate target neuron functioning and the reuptake proteins that generally terminate the neurotransmitter signal. Today a large majority of all drugs used to treat psychiatric disorders, as well as most drugs of abuse, still have as their initial targets proteins involved directly in neurotransmitter function.

Cellular and Molecular Mechanisms of Addiction

2017 ◽  
Author(s):  
Kathryn J. Reissner ◽  
Peter W. Kalivas
Keyword(s):  
Molecular Mechanisms ◽  
Drugs Of Abuse ◽  
Drug Seeking ◽  
Molecular Changes ◽  
Cellular Changes ◽  
Continued Use ◽  
Brain Reward ◽  
Social Use ◽  
The Brain

Exposure to drugs of abuse can be a reinforcing experience that, in vulnerable individuals, can lead to continued use and the development of an addiction disorder. Evidence indicates that the escalation in use and compulsive motivation to obtain the drug is linked to long-lasting cellular changes within the brain reward neurocircuitry. In this chapter we describe the stages of transition in use from social use to habitual relapse, and within that context we describe the implicated neurocircuitry, and the enduring cellular and molecular changes that occur within that circuitry, that may mediate the preoccupation with drug seeking in addiction-vulnerable individuals.

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