scholarly journals Zinc-responsive acral hyperkeratosis as a mimicker of cutaneous tuberculosis

2021 ◽  
Vol 12 (4) ◽  
pp. 445-447
Author(s):  
Vikash Paudel ◽  
Setu Mittal ◽  
Richa Tripathi
Keyword(s):  
Differential Diagnosis ◽  
Therapeutic Trial ◽  
Skin Disorders ◽  
Cutaneous Tuberculosis ◽  
Histopathological Features ◽  
Cutaneous Form ◽  
Anti Tubercular Therapy

Zinc-responsive acral hyperkeratosis is regarded as a novel entity masquerading numerous skin disorders, such as psoriasis, acral necrolytic erythema, and tuberculosis. Tuberculosis itself is a great imitator and so is its cutaneous form. Herein, we present the case of a female misdiagnosed as a case of tuberculosis verrucosa cutis due to clinical, biochemical, and histopathological features. The patient completed a full course of anti-tubercular therapy without an improvement and showed a dramatic response after a therapeutic trial of oral zinc. Thus, the patient was diagnosed as a case of zinc-responsive acral hyperkeratosis. In any form of acral hyperkeratotic lesions, zinc-responsive acral hyperkeratosis must be considered as a differential diagnosis.

Persistent urticarial rash in a newborn

2021 ◽  
Author(s):  
Iwona Dziewa ◽  
Timothy Hahn ◽  
Neeti Bhardwaj
Keyword(s):  
Differential Diagnosis ◽  
Inflammatory Markers ◽  
Initial Evaluation ◽  
Response To Treatment ◽  
Therapeutic Trial ◽  
Age Group ◽  
Diagnostic Modality ◽  
Urticarial Rash

We presented the case of a 1-month-old girl with diffuse urticarial-like rash since birth. The initial evaluation showed elevated inflammatory markers. The response to treatment helped to narrow the diagnosis. In this case, we explored the differential diagnosis of rashes in this age group and the role of a therapeutic trial of medication as a diagnostic modality.

scholarly journals Lupus Vulgaris: A Rare Case of Cutaneous Tuberculosis

2014 ◽  
Vol 41 (2) ◽  
pp. 57-58
Author(s):  
MA Chowdhury ◽  
TK Sikdar
Keyword(s):  
Medical Journal ◽  
Rare Case ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Lupus Vulgaris ◽  
Cutaneous Tuberculosis ◽  
Histological Sections ◽  
Epithelioid Granuloma ◽  
Affected Tissue ◽  
Anti Tubercular Therapy

Lupus vulgaris is an extremely chronic, progressive form of cutaneous tuberculosis. The earliest description of lupus vulgaris was given by Erasmus Wilson in 1865. It usually occurs through contagious extension of the disease from underlying affected tissue or hematogenous or lymphatic spread. A 55 years male, non diabetic, non hypertensive, non smoker, got himself admitted into Dermatology and Venereology Department of DMCH with the complaints of multiple ulcerated lesions over the left lower thigh and upper leg including knee for 8 years. Histological sections of skin revealed multiple epithelioid granuloma, multinucleated giant cells and infiltration of lymphocytes with areas of fibrosis and ESR was 80 in 1st hour. The patient was treated with anti tubercular therapy and cured completely. DOI: http://dx.doi.org/10.3329/bmj.v41i2.18811 Bangladesh Medical Journal 2012 Vol. 41 No. 2: 57-58

scholarly journals What is the appropriate duration of a therapeutic trial in cutaneous tuberculosis? Further observations

2007 ◽  
Vol 73 (4) ◽  
pp. 243 ◽  
Author(s):  
M Ramam ◽  
Trilokraj Tejasvi ◽  
Yashpal Manchanda ◽  
Sandeep Sharma ◽  
Rashmi Mittal
Keyword(s):  
Therapeutic Trial ◽  
Cutaneous Tuberculosis

scholarly journals Lupus vulgaris mimicking cutaneous leishmaniasis: A case report

2022 ◽  
Vol 13 (1) ◽  
pp. 53-56
Author(s):  
Nouf Faihan Bin Rubaian ◽  
Haya Fahad Alzamami ◽  
Gadah Abdulatif Alhosawi ◽  
Leena Abdulrahman Almuhaish
Keyword(s):  
Delayed Diagnosis ◽  
Punch Biopsy ◽  
Lupus Vulgaris ◽  
Cutaneous Tuberculosis ◽  
Dorsal Aspect ◽  
Skin Punch Biopsy ◽  
Diagnostic Difficulties ◽  
Anti Tubercular Therapy ◽  
The Right ◽  
Saudi Male

Lupus vulgaris (LV) is a progressive, chronic form of cutaneous tuberculosis (CTB). The head and neck regions are the most commonly affected sites, followed by the arms and legs. Occurring in unusual sites may pose diagnostic difficulties. Herein, we report a case of LV present on the dorsal aspect of the right hand in a twenty-year-old Saudi male. It was misdiagnosed as leishmaniasis as the patient lived in an area in which it was endemic, and was treated accordingly with no benefit. A skin punch biopsy was taken and the diagnosis of LV was confirmed. The lesion responded well to anti-tubercular therapy (ATT), yet healed with atrophic scarring. Although rare, clinicians must be aware of the importance of considering CTB as an important differential, as misdiagnosis or delayed diagnosis of this entity may eventually cause prolonged morbidity.

scholarly journals Angioleiomyoma as a rare cause of a painful subcutaneous nodule in the leg: a case report

Reumatismo ◽  
2019 ◽  
Vol 71 (2) ◽  
pp. 113-117
Author(s):  
A.A. Younis ◽  
R.A. Hamed ◽  
I.H. Abdulkareem
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Smooth Muscles ◽  
Subcutaneous Nodule ◽  
Leg Pain ◽  
Benign Tumors ◽  
Vascular Smooth Muscles ◽  
Histopathological Features ◽  
Rare Diagnosis

Angioleiomyomas are benign tumors originating in the vascular smooth muscles. The tumor typically presents as a painful, solitary, small subcutaneous nodule. Herein, we have described a case report of chronic leg pain due to angioleiomyoma. We outline the clinical, radiological and histopathological features of this rare diagnosis for a painful nodule of extremity. Although rare, angioleiomyoma should be included in the differential diagnosis of chronic leg pain.

scholarly journals Giant Cell Fibroma of Tongue: Understanding the Nature of an Unusual Histopathological Entity

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Wanjari Ghate Sonalika ◽  
Anshuta Sahu ◽  
Suryakant C. Deogade ◽  
Pushkar Gupta ◽  
Dinesh Naitam ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Oral Cavity ◽  
Giant Cell ◽  
Rare Case ◽  
Giant Cells ◽  
Basic Process ◽  
Broad Category ◽  
Histopathological Features

Giant cell fibroma (GCF) is a rare case with unique histopathology. It belongs to the broad category of fibrous hyperplastic lesions of the oral cavity. It is often mistaken with fibroma and papilloma due to its clinical resemblance. Only its peculiar histopathological features help us to distinguish it from them. The origin of the giant cell is still controversial. Data available is very sparse to predict the exact behavior. Hence, we report a case of GCF of tongue in a 19-year-old male. Special emphasis is given to understand the basic process of development of the lesion, nature of giant cells, and also the need for formation of these peculiar cells. Briefly, the differential diagnosis for GCF is tabulated.

scholarly journals Hailey-Hailey Disease: A Case Study Report with Review of Literature

2018 ◽  
pp. 13-17
Author(s):  
Shweta ◽  
Vijetha Rai ◽  
Kuladeepa Ananda Vaidhya ◽  
Sukesh
Keyword(s):  
Differential Diagnosis ◽  
Skin Disease ◽  
Autosomal Dominant ◽  
Clinical Course ◽  
Brick Wall ◽  
Review Of Literature ◽  
Histopathological Features ◽  
Study Report ◽  
Case Study Report

Hailey-Hailey disease (HHD), also called as familial benign chronic pemphigus, is a rare autosomal dominant blistering skin disease with waxing and waning in its clinical course. It is characterized by the presence of flaccid vesiculo-pustules, crusted erosions or expanding plaques in the areas of friction such as neck, axilla, groins, and perineum. His to pathologically shows suprabasal separations, inconspicuous dyskeratosis, acantholytic cells within the epidermis, giving a dilapidated brick wall appearance. Here we have discussed about the clinical and histopathological features of HHD and various differential diagnosis for this disease.

scholarly journals Solitary Mastocytoma of the Vulva

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Shasi Velusamy ◽  
Jayasree Karuthedath Areeppurath Mana ◽  
Chalissery Francis Mathew
Keyword(s):  
Differential Diagnosis ◽  
Case Reports ◽  
Surgical Excision ◽  
Rare Tumor ◽  
Unusual Site ◽  
Histopathological Features ◽  
Systemic Examination ◽  
Solitary Mastocytoma

Solitary mastocytoma of the skin is a rare tumor. Its occurrence in the vulva is extremely rare with only few case reports in the literature. We report a solitary mastocytoma of the vulva in a 10-year-old girl. Her systemic examination was unremarkable. The clinical and histopathological features were consistent with the diagnosis of solitary mastocytoma of the vulva. The follow-up after surgical excision was uneventful. The purpose of this communication is (i) to report a case of solitary mastocytoma occurring in an unusual site, the vulva and to show that (ii) in this case age at presentation is 10 years with infancy as common age of presentation of solitary mastocytoma, and to show that (iii) in appropriate setting this should be included in the differential diagnosis of vulval swelling.

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