scholarly journals Giant Cell Fibroma of Tongue: Understanding the Nature of an Unusual Histopathological Entity

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Wanjari Ghate Sonalika ◽  
Anshuta Sahu ◽  
Suryakant C. Deogade ◽  
Pushkar Gupta ◽  
Dinesh Naitam ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Oral Cavity ◽  
Giant Cell ◽  
Rare Case ◽  
Giant Cells ◽  
Basic Process ◽  
Broad Category ◽  
Histopathological Features

Giant cell fibroma (GCF) is a rare case with unique histopathology. It belongs to the broad category of fibrous hyperplastic lesions of the oral cavity. It is often mistaken with fibroma and papilloma due to its clinical resemblance. Only its peculiar histopathological features help us to distinguish it from them. The origin of the giant cell is still controversial. Data available is very sparse to predict the exact behavior. Hence, we report a case of GCF of tongue in a 19-year-old male. Special emphasis is given to understand the basic process of development of the lesion, nature of giant cells, and also the need for formation of these peculiar cells. Briefly, the differential diagnosis for GCF is tabulated.

scholarly journals Tonsillar tuberculosis : A case report

2016 ◽  
Vol 6 (12) ◽  
pp. 1048-1050
Author(s):  
S Karki ◽  
D Karki
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Pulmonary Tuberculosis ◽  
Oral Cavity ◽  
Histopathological Examination ◽  
Giant Cells ◽  
Rare Entity ◽  
Definite Diagnosis ◽  
Active Pulmonary Tuberculosis ◽  
Clinical Differential Diagnosis

Tuberculosis of the oral cavity which is an uncommon occurrence can be primary or secondary. In the absence of active pulmonary tuberculosis, isolated tonsillar tuberculosis is rare. Herein, we report two cases of bilateral tonsillar tuberculosis who presented as recurrent sore throat for which tonsillectomy was done. No active primary pulmonary lesion was found in these cases. Histopathological examination revealed caseating epithelioid granulomas with Langhans giant cells. Ziehl Neelson stain for acid fast bacilli was positive in one case. Tonsillar tuberculosis, though a rare entity, should be considered in the clinical differential diagnosis of tonsillar lesions. Histopathological examination with Ziehl Neelson stain should be performed for definite diagnosis.

scholarly journals Nevus of Ota with Rare Palatal Involvement: A Case Report with Emphasis on Differential Diagnosis

2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Gaurav Sharma ◽  
Archna Nagpal
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Oral Cavity ◽  
Rare Case ◽  
Indian Subcontinent ◽  
English Literature ◽  
Melanocytic Nevus ◽  
Oral Manifestations ◽  
Nevus Of Ota ◽  
The Face

Nevus of Ota, a dermal melanocytic nevus, is rare in the Indian subcontinent. It presents as a brown, blue, or gray patch on the face and is within the distribution of the ophthalmic and maxillary branches of the trigeminal nerve. The oral cavity is infrequently involved in nevus of Ota. Only 11 cases have been documented in the English literature. We report a rare case of intraoral nevus of Ota in a 22-year-old male patient. This paper focuses on the differential diagnosis of oral manifestations of nevus of Ota to assist in proper followup to avert malignant transformation.

scholarly journals IDIOPATHIC GIANT CELL MYOCARDITIS PRESENTING AS SUDDEN CARDIAC DEATH- A RARE CASE REPORT

2014 ◽  
Vol 04 (02) ◽  
pp. 142-143
Author(s):  
Harish S. Permi
Keyword(s):  
Giant Cell ◽  
Rare Case ◽  
Plasma Cells ◽  
Myocardial Necrosis ◽  
Giant Cells ◽  
Cellular Infiltration ◽  
Healthy Male ◽  
Giant Cell Myocarditis ◽  
Unexplained Death ◽  
Rare Case Report

Abstract:Idiopathic giant cell myocarditis is a disease of relatively young, predominantly healthy adults which is usually known to cause death in more than half of the cases of sudden death due to heart failure and ventricular arrhythmia. The typical histological features are myocardial necrosis and a rich cellular infiltration of lymphocytes, macrophages, eosinophils, plasma cells and multinucleated giant cells. We report a rare case of idiopathic giant cell myocarditis in a 32 year old healthy male who died suddenly and stress the need to consider as one of the cause of unexplained death in young adults on autopsy.

Towards better understanding of giant cell granulomas of the oral cavity

2021 ◽  
pp. jclinpath-2020-206858
Author(s):  
Atif Ahmed ◽  
Aparna Naidu
Keyword(s):  
Oral Cavity ◽  
Giant Cell ◽  
Giant Cell Tumour ◽  
Bone Cyst ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Biological Behaviour ◽  
Precise Diagnosis ◽  
Insight Into ◽  
Recent Insight

Giant cell granulomas are enigmatic lesions of the oral cavity characterised by a peculiar combined proliferation of mononuclear and multinucleated giant cells in a mesenchymal stromal background. Central and peripheral giant cell granulomas may have similar pathogenesis and histology but differ in their location and biological behaviour. It is important to differentiate them from other giant cell lesions that can occur in the oral cavity, such as giant cell tumour of the bone, aneurysmal bone cyst, brown tumour of hyperparathyroidism, and giant cell lesions of Ramon syndrome, Noonan syndrome, neurofibromatosis and Jaffe-Campanacci syndrome. A recent insight into their molecular genetics and pathogenesis, with identification of KRAS, FGFR1 and TRPV4 mutations, allows for better diagnostic differentiation and opens the door to the use of pathway inhibitors in the treatment of recurrent or dysmorphic lesions. In this review, we provide an updated summary of the clinical and pathological features of oral cavity giant cell granulomas that help with their precise diagnosis and management.

scholarly journals Rare case of intra-oral palatal (soft palate) fibro-lipoma

2021 ◽  
Vol 7 (5) ◽  
pp. 885
Author(s):  
Manit M. Mandal ◽  
Ajay J. Panchal ◽  
Rakesh Kumar ◽  
Parth B. Kapadia ◽  
Neel Parmar
Keyword(s):  
Differential Diagnosis ◽  
Oral Cavity ◽  
Nasal Obstruction ◽  
Male Patient ◽  
Soft Palate ◽  
Rare Case ◽  
Endoscopic Examination ◽  
Chief Complaints ◽  
Dual Route

<p>Amongst various differential diagnoses possible for intra-oral (palatal) mass, possibility of fibro-lipoma is extremely rare but documented in literature, and hence should be a consideration. Such patient requires thorough evaluation and step-wise approach to treat. This case study documents for a 30-year-old male patient presenting with such mass and chief complaints of post nasal drip, nasal obstruction (right side&gt;left side) and intermittent headache for 3 years. After radiological and endoscopic examination, the mass was surgically removed in toto via dual route (trans-oral and endoscopic).  Lipomas are uncommon tumors in the oral cavity, and palate being the rarest amongst them as is our case. It would be strongly advocated to keep lipoma in the differential diagnosis when evaluating a palatal mass. Also, it is worth mentioning and recommending that a careful radiological examination of large lesions arising from the palate is a must before approaching for surgery.</p>

scholarly journals Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Vani Krishnamurthy ◽  
Sheela Devi C. Shivalingiah ◽  
Sunila Ravishankar ◽  
Gubbanna V. Manjunath
Keyword(s):  
Giant Cell ◽  
Rare Case ◽  
Giant Cells ◽  
Undifferentiated Carcinoma ◽  
Rare Tumor ◽  
Cell Type ◽  
Epithelial Component ◽  
Giant Cell Type

Carcinosarcoma is a rare tumor composed of variable proportions of carcinomatous and sarcomatous elements and comprises less than one percent of all gallbladder malignancies. In most reported cases of carcinosarcoma of gallbladder, the epithelial component is adenocarcinoma. The mesenchymal component varies from homogenous sarcoma to more heterotopic elements like malignant bone, cartilage, and other mesenchymal tissues. We report a rare case of carcinosarcoma of the gallbladder in an 83-year-old male, with the carcinomatous component represented by undifferentiated carcinoma (spindle and giant cell type with osteoclastic giant cells) and the mesenchymal component seen as foci of chondrosarcoma.

Giant Cells and Giant Cell Lesions of the Oral Cavity: a Review

2015 ◽  
Vol 1 (1) ◽  
pp. 79
Author(s):  
Shikha Shrivastava ◽  
OP Shrivastava ◽  
Manish Saxena ◽  
Chetan Shrivastava ◽  
Ayushi Shrivastava
Keyword(s):  
Oral Cavity ◽  
Giant Cell ◽  
Giant Cells

scholarly journals Collision Lesion of Mandible—Coexistence of Keratocystic Odontogenic Tumor with Central Giant Cell Granuloma: A Rare Case Report

2013 ◽  
Vol 14 (2) ◽  
pp. 355-359 ◽  
Author(s):  
C Prashanthi ◽  
Vinayak Karun ◽  
Mahesh Melkundi ◽  
Sanjay Nyamati ◽  
Annapoorna HB
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Rare Case ◽  
Giant Cells ◽  
Odontogenic Tumor ◽  
Biological Behavior ◽  
Keratocystic Odontogenic Tumor ◽  
Giant Cell Granuloma ◽  
Central Giant Cell Granuloma ◽  
Rare Case Report

ABSTRACT Aim and background An odontogenic keratocyst (OKC) or keratocystic odontogenic tumor (KCOT) and giant cell granuloma (GCG) in the jaws are common lesions which have been studied extensively in detail over the years. However, a lesion showing features of both is exceptionally rare and is reported only twice in the literature till date. Case description A rare case of OKC in mandible showing foci of GCG like areas is reported in a 29 years old male patient. Conclusion It seems to be a collision lesion, though the possibility of KCOT showing a reactive response to form giant cells or it being a rare variant cannot be totally ruled out. Clinical significance This entity requires aggressive treatment since biological behavior of this unique lesion is difficult to predict unless more of such lesions are reported and followed up in future. How to cite this article Ravi SB, Prashanthi C, Karun V, Melkundi M, Nyamati S, Annapoorna HB. Collision Lesion of Mandible: Coexistence of Keratocystic Odontogenic Tumor with Central Giant Cell Granuloma: A Rare Case Report. J Contemp Dent Pract 2013;14(2):355-359.

scholarly journals Congenital Giant Cell Fibroma – A Case Report

2020 ◽  
Vol 26 (1) ◽  
pp. 21-28
Author(s):  
Mohd Ridzuan Mohd Razi ◽  
Nabilah Sawani Harith ◽  
Nur Fazilah Mohd Tahir ◽  
Nishanti Selvaraj
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Giant Cell ◽  
Rare Case ◽  
Asymptomatic Patient ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Paediatric Dentistry ◽  
Alveolar Ridge ◽  
Alveolar Region

Background: This paper aims to report a rare case of congenital giant cell fibroma (GCF). To the best of our knowledge, this is the first reported case of GCF in new-born. Case Report: A healthy one-month-old baby boy was referred to Department of Paediatric Dentistry for management of swelling on the upper left alveolar region which presented since birth. Clinical examination demonstrated a well define firm swelling over the upper left alveolar ridge, otherwise the swelling was asymptomatic. Patient was monitored periodically. At 1 year and 9 months of age, there were episodes of ulcerations and bleeding from the lesion as a result of trauma from eruption of opposing teeth. Surgical excision of the lesion was carried out under general anaesthesia. The histopathological examination (HPE) report interpreted the lesion as GCF. Conclusion: GCF is rare fibrous lesion that could be diagnosed only on HPE. Although it is an uncommon congenital lesion, GCF should be considered as one of differential diagnosis of swelling over the gingiva.

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