scholarly journals Extragenital lichen sclerosus of the breast and silicone breast implants

2022 ◽  
Vol 13 (1) ◽  
pp. 67-69
Author(s):  
Alberto Goldman ◽  
Uwe Wollina
Keyword(s):  
Skin Biopsy ◽  
Breast Implant ◽  
Lichen Sclerosus ◽  
Breast Implants ◽  
Autoimmune Disorders ◽  
Silicone Breast Implant ◽  
Silicone Breast Implants ◽  
Inflammatory Dermatosis ◽  
Basal Keratinocyte

Lichen sclerosus of the breast (LSB) is an uncommon inflammatory dermatosis of an incompletely understood pathogenesis. Herein, we report the case of a 29-year-old female who developed LSB 23 years after a silicone breast implant. A diagnostic skin biopsy revealed the typical three-layered pathology of an atrophic epidermis with the loss of rete ridges and basal keratinocyte vacuolization, a subepidermal band of sclerosis, and a lichenoid infiltrate of lymphocytes beneath that band. We discuss the possible relationship between silicone breast implants and autoimmune disorders.

scholarly journals An Unusual Case of Fever and Lymphadenopathy

2009 ◽  
Vol 8 (2) ◽  
pp. 73-74
Author(s):  
John Ho ◽  
Keyword(s):  
Unusual Case ◽  
Breast Implant ◽  
Breast Implants ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Medical Team ◽  
Radiological Imaging ◽  
Silicone Breast Implant ◽  
Silicone Breast Implants ◽  
Breast Implant Rupture

A 62 year old female presented to the acute medical team with headache, fevers and enlarged axillary lymph nodes. Initial biochemical, microbiological and immunological investigations were normal. However, radiological imaging revealed that her silicone breast implants had ruptured, which may have been responsible for her presentation. A brief overview of the clinical features and management of silicone breast implant rupture is provided.

The Silicone Gel Breast Implant Controversy—A Chronology of Recent Regulations and Decisions

1993 ◽  
Vol 10 (2) ◽  
pp. 89-93
Author(s):  
Howard A. Tobin
Keyword(s):  
Drug Administration ◽  
Breast Implant ◽  
Breast Implants ◽  
Press Coverage ◽  
Silicone Breast Implants ◽  
Consumer Activism ◽  
Silicone Gel ◽  
Congressional Investigations ◽  
Regulatory Actions

This article summarizes the regulatory actions of the Food & Drug Administration as related to gel-filled silicone breast implants. It also relates the actions to the influences of outside forces such as press coverage, congressional investigations, and consumer activism.

IgA Myeloma and Still’s Disease in a patient with bilateral silicone breast implants

Open Medicine ◽  
2008 ◽  
Vol 3 (2) ◽  
pp. 229-231
Author(s):  
Punit Yadav ◽  
Iwona Ordyniec ◽  
Salem Madi
Keyword(s):  
Bone Marrow ◽  
Breast Implant ◽  
Breast Implants ◽  
Bone Marrow Examination ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Silicone Breast Implants ◽  
Still's Disease ◽  
Adult Onset Still's Disease

AbstractWe report a case of a woman with bilateral silicone breast implants who presented with recurrent high grade fever, joint and muscle aches. An extensive workup failed to indicate an infectious source of her illness, so based on her symptoms a clinical diagnosis of Adult Onset Still’s disease was made. However, subsequent investigations revealed raised IgA paraprotein levels in her serum which led to a bone marrow examination. Bone marrow examination was consistent with IgA Myeloma. Chemotherapy was commenced which led to a decrease in the paraprotein level. In addition, she was treated with non steroidal anti-inflammatory drugs and intraarticular steroid injections which provided marked symptomatic relief. The case indicates a possible association of Myeloma and Adult Onset Still’s Disease in a patient with bilateral silicone breast implant.

Granuloma of Silicone Breast Implants A case report and literature review

2019 ◽  
Vol 70 (3) ◽  
pp. 940-942
Author(s):  
Irina Jari ◽  
Alexandru G. Naum ◽  
Liliana Gheorghe ◽  
Dragos Negru ◽  
Paloma Horjinec ◽  
...  
Keyword(s):  
Rare Complication ◽  
Breast Implant ◽  
Breast Implants ◽  
Breast Ultrasound ◽  
Synthetic Polymer ◽  
Silicone Breast Implants ◽  
Implant Placement ◽  
Clinical Literature ◽  
Mri Scans ◽  
Breast Implant Rupture

Silicone, a synthetic polymer containing the element silicon, has been used for breast implants. Complications resulting from the placement of silicone breast implants are becoming more frequent in clinical practice. Breast implant rupture is common and poses challenges for radiologists and physicians. Radiologists must be familiar with the normal and abnormal findings of common implants. Clinically apparent silicone granulomas are a relatively rare complication of breast implant placement and surgical resection is indicated when they are symptomatic or of diagnostic concern. The objective of this study is to examine the latest generations of silicone breast implants and the clinical literature related to silicone granulomas together with a case of silicon granuloma diagnosed in our service. The findings are based on diagnostic breast Ultrasound and MRI scans performed at our service.

scholarly journals Diagnosis, investigation and management of breast implant illness

2021 ◽  
Vol 4 (1) ◽  
pp. 9-21
Author(s):  
Daniel WH Wong ◽  
Tai K Lam
Keyword(s):  
Case Reports ◽  
Breast Implant ◽  
Case Series ◽  
Breast Implants ◽  
Silicone Implants ◽  
Exact Nature ◽  
Cochrane Central Register ◽  
Case Control Studies ◽  
Silicone Breast Implants ◽  
Retrospective Cohort Studies

Introduction: An increasing pool of literature proposes a link between silicone implants and autoimmune-related symptoms known colloquially as breast implant illness (BII). We describe the history of BII, reported symptoms, risk factors and previously published diagnostic criteria to aid clinicians in the diagnosis, investigations and management of patients presenting with symptoms that they attribute to their silicone breast implants. Methods: A literature search was performed using MEDLINE®, the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials (CENTRAL), the Database of Abstracts of Reviews of Effect (DARE) and PubMed in September 2018. The search terms ‘autoimmune inflammatory syndrome induced by adjuvants’, ‘breast implants’ and ‘silicone’ were used alone and in combination. Results: Thirty-four studies were reviewed including three case reports, 12 case series, 14 retrospective cohort studies, four case control studies and one prospective cohort study. Within this cohort, 18 studies were found regarding the explantation of implants relating to BII. Conclusion: Studies have demonstrated no association between silicone breast implants and any known autoimmune diseases, but there exists a pool of literature suggestive of a relatively undefined condition colloquially known as BII. Serological testing and imaging play an important role in the assessment of patients to exclude other pathology, but these tests remain non-diagnostic for BII. Although medical treatment has shown promise, there is no established treatment for patients. The surgical explantation of implants appears to have positive outcomes for patients; however, the exact nature of the surgery required to achieve this remains unclear.

scholarly journals Research Related to Capsular Contracture after Breast Augmentation for Cosmetic or Reconstructive Purposes

2019 ◽  
Vol 70 (5) ◽  
pp. 1619-1624
Author(s):  
Silviu Adrian Marinescu ◽  
Dan Mircea Enescu ◽  
Catalin Gheorghe Bejinariu ◽  
Carmen Giuglea
Keyword(s):  
Breast Augmentation ◽  
Cell Lymphoma ◽  
Breast Implant ◽  
Capsular Contracture ◽  
Breast Implants ◽  
Large Cell ◽  
Upward Trend ◽  
Silicone Breast Implants ◽  
Number Of Patients ◽  
Alloplastic Breast Reconstruction

The upward trend of patients opting for elective breast augmentation, as well as the large number of patients benefiting from alloplastic breast reconstruction, require further studies on the safety profile of these techniques. Without any doubt, the incidence of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) has drawn attention to the possible unknown complications characteristic of these procedures, creating the context of further studies devoted to this issue. The present research examines the capsular contracture rate on a group of 253 patients between 2015 and 2019, also proposing a scoring system based on the integration of the main diagnostic criteria related to the capsular contracture. The results of the literature review indicate that a lower incidence of capsular contracture could be achieved by using the newest techniques in the field involving the application of chemical substances on the surface of the latest generation of silicone breast implants.

THE $4.3 BILLION MISTAKE

PEDIATRICS ◽  
1994 ◽  
Vol 94 (3) ◽  
pp. 290-290
Author(s):  
J. F. L.
Keyword(s):  
Scientific Method ◽  
Breast Implant ◽  
Breast Implants ◽  
Economic Incentive ◽  
Epidemiological Studies ◽  
Silicone Implants ◽  
Silicone Breast Implant ◽  
Contingency Fees ◽  
The Media ◽  
Set Up

Three recent epidemiological studies of purported links between breast implants and a variety of ailments, notably the skin hardening disease scleroderma, have concluded that the linkage simply cannot be established. Gee, that's nice to know. Better late than never. Too bad, though, that in our era the scientific method can't compete anymore with lawyers marauding after some $1 billion in contingency fees, politically correct mind-sets in the media, or Dr. Kessler's Food and Drug Administration. It's too bad, because as a result of the atmosphere of fright created by this triumvirate, nearly all companies withdrew from the silicone breast-implant market. Mastectomy patients, past and future, now face a destroyed market for silicone implants. It has to be understood that these plaintiffs' lawyers have a huge economic incentive in the outcome of such cases because they get an enormous percentage cut of any settlement. It is in their economic interest to make the stories of diseases related to silicone implants as lurid and horrible as possible, because it drives deep-pockets defendants toward settlements like the $4.3 billion pot set up by Dow Corning, Bristol-Myers, Baxter Labs, 3M, and others in this case. Only about 22 lawyers will be divvying up most of the $1 billion in contingency fees.

Hydrogel-Filled Mammary Prosthesis

1998 ◽  
Vol 15 (3) ◽  
pp. 259-262
Author(s):  
Guy-Henri Muller
Keyword(s):  
Breast Implant ◽  
Breast Implants ◽  
Living Tissue ◽  
Silicone Breast Implant ◽  
Postoperative Results ◽  
Silicone Gel ◽  
Mammary Prosthesis ◽  
One Year ◽  
Visual Results ◽  
Better Than

Introduction: The silicone breast implant controversy and the moratorium on the use of silicone-gel-filled breast implants in the U.S., Canada, and France has led to a search for substitutes for silicone-gel implants that are safe, pliable, and still firm enough to hold its shape. Hydrogel is being evaluated as an alternative to silicone gel for filling breast implants. Materials and Methods: Eighteen hundred ninety hydrogel-filled breast implants were inserted into patients in France and Italy between 1992 and 1993. The postoperative results of these procedures were reviewed. Results: Twelve implant ruptures occurred at the time of insertion secondary to too small an incision and lack of prewarming of the implant. Two ruptures went unnoticed and were satisfactorily resolved with a revision of the first procedure. One capsule contracture occurred within one year. Visual results according to patients and surgeons were satisfactory. The palpable results are less favorable than silicone-gel implants, but better than saline-filled implants. Discussion: Hydrogel is biocompatible. The breakdown products of the implant filler, if they migrate outside the shell, should not be toxic. Because hydrogel is a biomaterial filler to which water is added to reach an equilibrium point, it mimics the consistency of living tissue. Conclusions: Hydrogel appears to be a favorable substitute for silicone gel.

Kikuchi-Fujimoto Disease-Like Inflammatory Reaction in a Silicone Breast Implant Seroma

2020 ◽  
Vol 64 (4) ◽  
pp. 386-389
Author(s):  
José A. Jiménez-Heffernan ◽  
Patricia Muñoz-Hernández ◽  
Carmen Bárcena
Keyword(s):  
Lymph Nodes ◽  
Inflammatory Reaction ◽  
Breast Implant ◽  
Breast Implants ◽  
Large Cell ◽  
Needle Aspiration ◽  
Cervical Lymph Nodes ◽  
Cytologic Examination ◽  
Silicone Breast Implants ◽  
Autoimmune Etiology

Introduction: Kikuchi-Fujimoto disease (KFD) may have an autoimmune etiology and some cases have been associated with silicone breast implants. Cytomorphologic features of the disease have been well characterized by fine-needle aspiration of lymph nodes. They are so specific as to permit a precise cytologic diagnosis. Cytologic features have not been reported in fluid specimens. Case: A 33-year-old female presented with a unilateral periprosthetic silicone breast seroma. The fluid was drained, and cytological analysis revealed numerous lymphocytes with no neutrophils, karyorrhectic nuclear debris, and peculiar histiocytes with eccentrically located nuclei showing a crescentic shape. Many of those histiocytes showed intracellular apoptotic debris. Conclusion: A Kikuchi disease-like inflammatory reaction is possible not only in axillary and cervical lymph nodes of patients with silicone breast implants but also in breast seromas. There is still not enough evidence to establish if there is an association between KFD and breast implants. A detailed cytologic examination of periprosthetic silicone breast seromas may help answer this question. In any case, pathologists must be aware of this possibility. Cytologic features are characteristic enough to permit differentiation from breast implant-associated anaplastic large-cell lymphoma.

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