scholarly journals SYNTHESIS AND STUDY OF SOME NOVEL BENZIMIDAZOLE ANALOGS AS POTENTIAL ANTIULCER AGENTS

2012 ◽  
Vol 2 (3) ◽  
Author(s):  
Avinash Patil ◽  
Swastika Ganguly ◽  
Jogendra Hundiwale ◽  
Santosh Tayade
Keyword(s):  
Antiulcer Agents

Evaluation of antiulcer agents with a human adenocarcinoma cell line (AGS)

1996 ◽  
Vol 129 (1-2) ◽  
pp. 103-112 ◽  
Author(s):  
Hongjian Zheng ◽  
Praful K. Shah ◽  
Kenneth L. Audus
Keyword(s):  
Cell Line ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Antiulcer Agents

Antiulcer agents. 4. Conformational considerations and the antiulcer activity of substituted imidazo[1,2-a]pyridines and related analogs

1989 ◽  
Vol 32 (8) ◽  
pp. 1686-1700 ◽  
Author(s):  
James J. Kaminski ◽  
Chester Puchalski ◽  
Daniel M. Solomon ◽  
Razia K. Rizvi ◽  
David J. Conn ◽  
...  
Keyword(s):  
Antiulcer Activity ◽  
Antiulcer Agents

Pharmacognostic Studies of the Stem Bark of Enantia chlorantha Oliver (Annonaceae)

2015 ◽  
Vol 19 ◽  
pp. 122-125
Author(s):  
TL Ohemu ◽  
A Agunu ◽  
DG Dafam ◽  
PN Olotu
Keyword(s):  
Cell Wall ◽  
Calcium Oxalate ◽  
Stem Bark ◽  
Standard Methods ◽  
Antiulcer Agents ◽  
Physiochemical Parameters ◽  
Microscopic Studies ◽  
Wall Materials ◽  
Cell Wall Materials

Enantia chlorantha Oliver (Annonaceae) is commonly known as African yellow wood used as hepatoprotective, antiviral, antimalarial, antibacterial and antiulcer agents. The study was aimed to investigate the pharmacognostic and physiochemical parameters of E. chlorantha stem bark. The macroscopy, microscopy and chemomicroscopy of E. chlorantha were carried out using standard methods. Cell wall materials, cell inclusions and other diagnostic characters, which can aid in the easy and proper identification of the plant, were identified. The microscopic studies revealed the presence of sclereids, fibres, medullary ray, and calcium oxalate prisms. The physiochemical evaluation of was done, in order to ascertain quality and purity. This study provides additional useful information needed for determination of its identity and quality that can be added as enrichment of the pharmacopoeia of the plant.Keywords: Pharmacognostic, Stem Bark, Enantia chlorantha

Biological Evaluations of some Synthesized Pyrimidothieno [2,3-b] Pyrimidine Candidates as Antiulcer Agents

2015 ◽  
Vol 11 (7) ◽  
pp. 840-845 ◽  
Author(s):  
Abd El-Galil E. Amr ◽  
Mohamed A. Al- Omar ◽  
Mohamed M. Abdalla
Keyword(s):  
Antiulcer Agents

Drug Interactions with Antiulcer Agents: Considerations in the Treatment of Acid-Peptic Disease

1994 ◽  
Vol 7 (4) ◽  
pp. 177-195 ◽  
Author(s):  
Lynda S. Welage ◽  
Rosemary R. Berardi
Keyword(s):  
Drug Interactions ◽  
Drug Selection ◽  
Antiulcer Drug ◽  
Detailed Understanding ◽  
Pharmacodynamic Response ◽  
Antiulcer Agents ◽  
Peptic Disease ◽  
Clinical Consequences ◽  
Insight Into

All of the antiulcer agents have been implicated in drug interactions. These agents generally influence the absorption, metabolism, or elimination of other medications. However, these interactions can lead to alterations in pharmacodynamic response. The mechanisms by which antiulcer agents produce drug interactions differ among the agents. It is beyond the scope of this article to review all of the drug interactions that have been reported with antiulcer agents. However, it is the intent to provide the reader with a detailed understanding of the mechanisms by which antiulcer agents may interact with other medications and to provide insight into factors that may influence the potential magnitude or clinical consequences of these interactions. An understanding of antiulcer drug interactions will aid pharmacists in assisting clinicians with drug selection and/or monitoring of drug interactions. Specifically, pharmacists can assist with the identification of potential antiulcer drug interactions and develop strategies designed to minimize adverse consequences of these interactions.

scholarly journals A direct comparison of effects of antiulcer agents on the healing of gastric and duodenal ulcers in rats.

1994 ◽  
Vol 64 ◽  
pp. 88
Author(s):  
Mikio Ito ◽  
Tetsuya Seaami ◽  
Kazuhide Inaguma ◽  
Yoshio Suzuki
Keyword(s):  
Duodenal Ulcers ◽  
Antiulcer Agents

scholarly journals Natural Products as Gastroprotective and Antiulcer Agents: Recent Developments

2008 ◽  
Vol 3 (12) ◽  
pp. 1934578X0800301 ◽  
Author(s):  
Rosa Tundis ◽  
Monica R Loizzo ◽  
Marco Bonesi ◽  
Federica Menichini ◽  
FilomenaConforti ◽  
...  
Keyword(s):  
Natural Products ◽  
Current Knowledge ◽  
Gastrointestinal Diseases ◽  
Chronic Inflammatory Disease ◽  
Future Perspectives ◽  
Duodenal Ulcers ◽  
Antiulcer Agents ◽  
Alternative Drug ◽  
Recent Developments ◽  
Upper Gastrointestinal

Peptic ulcer, one of the most common gastrointestinal diseases, is a chronic inflammatory disease characterized by ulceration in the regions of the upper gastrointestinal tract where parietal cells are found and where they secrete hydrochloric acid and pepsin. The anatomical sites where ulcer occurs commonly are stomach and duodenum, causing gastric and duodenal ulcer, respectively. Physiopathology of ulcer is due to an imbalance between aggressive factors, such as acid, pepsin, Helicobacter pylori and non-steroidal anti-inflammatory agents, and local mucosal defensive factors, such as mucus bicarbonate, blood flow and prostaglandins. Several drugs are widely used to prevent or treat gastro-duodenal ulcers. These include H2-receptor antagonists, proton pump inhibitors and cytoprotectives. Due to problems associated with recurrence after treatment, there is therefore the need to seek alternative drug sources against ulcers. In recent years, a widespread search has been launched to identify new gastroprotective drugs from natural sources. The aim of the present review is to highlight the recent advances in current knowledge on natural products as gastroprotective and antiulcer agents and consider the future perspectives for the use of these compounds.

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