Orthotic therapy in the management of osteoarthritis

1992 ◽  
Vol 82 (3) ◽  
pp. 136-139 ◽  
Author(s):  
JA Thompson ◽  
MB Jennings ◽  
W Hodge
Keyword(s):  
Drug Therapy ◽  
Pain Relief ◽  
Foot And Ankle ◽  
Inflammatory Drug ◽  
Treatment Regimens ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Term Management

The authors evaluate the use of orthoses as a primary therapeutic means in the long-term management of patients with osteoarthritis of the foot and ankle. A comparison of the amount of pain relief experienced by 64 subjects (mean age 63 years) with different treatment regimens for osteoarthritis was made to determine the role orthoses played in helping to reduce or eliminate pain. One hundred percent of the subjects wearing orthoses only for relief of pain had a statistically significant longer period of pain relief than those on nonsteroidal anti-inflammatory drugs. Fifty-five percent of the subjects using orthoses and nonsteroidal anti-inflammatory drug therapy also had a statistically significant longer period of pain relief than those receiving nonsteroidal anti-inflammatory drug therapy only.

Potential complications of nonsteroidal anti-inflammatory drug therapy

1989 ◽  
Vol 79 (12) ◽  
pp. 605-614
Author(s):  
GD Corrigan ◽  
L Pantig-Felix ◽  
IO Kanat
Keyword(s):  
Health Care ◽  
Patient Satisfaction ◽  
Drug Therapy ◽  
Side Effects ◽  
Mechanism Of Action ◽  
Drug Class ◽  
Inflammatory Drug ◽  
The Us ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Since indomethacin was first marketed, some 40 years ago, the class of nonsteroidal anti-inflammatory drugs has grown larger than any other drug class in history. At present, there are at least 25 such drugs being used in the US and abroad, both clinically and in research. Despite their widespread use, their implications to health care are just beginning to be understood. The authors review updated theories on the mechanism of action, side effects, and drug interactions of nonsteroidal anti-inflammatory drug therapy. Proposed guidelines for monitoring their use are given. A more thorough understanding of the risks-to-benefits ratio is provided in an effort to achieve maximum patient satisfaction and safety.

Bisphosphonate Increases Risk of Peptic Ulcer in Rheumatoid Arthritis Patients On Long-Term Non-Steroidal Anti-Inflammatory Drug Therapy

2008 ◽  
Vol 67 (5) ◽  
pp. AB276
Author(s):  
Masafumi Kusunoki ◽  
Kazumasa Miyake ◽  
Mariko Umezawa ◽  
Tomotaka Shindo ◽  
Nobue Ueki ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Peptic Ulcer ◽  
Drug Therapy ◽  
Inflammatory Drug ◽  
Anti Inflammatory

Long-term management of atopic dermatitis in infants with topical pimecrolimus, a nonsteroid anti-inflammatory drug

2002 ◽  
Vol 110 (2) ◽  
pp. 277-284 ◽  
Author(s):  
Alexander Kapp ◽  
Kim Papp ◽  
Ann Bingham ◽  
Regina Fölster-Holst ◽  
Jean-Paul Ortonne ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Inflammatory Drug ◽  
Anti Inflammatory ◽  
Term Management

scholarly journals LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY

2010 ◽  
Vol 0 (3) ◽  
pp. 23 ◽  
Author(s):  
Natalya Vladimirovna Chichasova ◽  
M Z Kanevskaya ◽  
G R Imametdinova ◽  
E V Igolkina ◽  
E L Nasonov
Keyword(s):  
Rheumatoid Arthritis ◽  
Drug Therapy ◽  
Long Term Outcomes ◽  
Inflammatory Drug ◽  
Anti Inflammatory

scholarly journals Disease-Modifying Effects of Long-Term and Continuous Use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) in Spondyloarthritis

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Rebecca S. Y. Wong
Keyword(s):  
Pain Relief ◽  
Adverse Effects ◽  
Musculoskeletal System ◽  
First Line ◽  
Disease Research ◽  
Inflammatory Drugs ◽  
Disease Modifying ◽  
Anti Inflammatory ◽  
Continuous Use

Spondyloarthritis or spondyloarthropathy (SpA) is a group of related rheumatic disorders, which presents with axial and nonaxial features, affecting structures within the musculoskeletal system, as well as other bodily systems. Both pharmacological and nonpharmacological therapeutic options are available for SpA. For decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been used as the first-line drugs to treat the disease. Research has shown that other than pain relief, NSAIDs have disease-modifying effects in SpA. However, to achieve these effects, continuous and/or long-term NSAID use is usually required. This review will give an overview of SpA, discuss NSAIDs and their disease-modifying effects in SpA, and highlight some of the important adverse effects of long-term and continuous NSAID use, particularly those related to the gastrointestinal, renal, and cardiovascular systems.

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