scholarly journals The role of PDF neurons in setting the preferred temperature before dawn in Drosophila

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Xin Tang ◽  
Sanne Roessingh ◽  
Sean E Hayley ◽  
Michelle L Chu ◽  
Nobuaki K Tanaka ◽  
...  
Keyword(s):  
Body Temperature ◽  
Neural Circuit ◽  
Sleep Regulation ◽  
Temperature Preference ◽  
Preferred Temperature ◽  
Pigment Dispersing Factor ◽  
Temperature Rhythm ◽  
Body Temperature Rhythm ◽  
Serotonin Signaling

Animals have sophisticated homeostatic controls. While mammalian body temperature fluctuates throughout the day, small ectotherms, such as Drosophila achieve a body temperature rhythm (BTR) through their preference of environmental temperature. Here, we demonstrate that pigment dispersing factor (PDF) neurons play an important role in setting preferred temperature before dawn. We show that small lateral ventral neurons (sLNvs), a subset of PDF neurons, activate the dorsal neurons 2 (DN2s), the main circadian clock cells that regulate temperature preference rhythm (TPR). The number of temporal contacts between sLNvs and DN2s peak before dawn. Our data suggest that the thermosensory anterior cells (ACs) likely contact sLNvs via serotonin signaling. Together, the ACs-sLNs-DN2s neural circuit regulates the proper setting of temperature preference before dawn. Given that sLNvs are important for sleep and that BTR and sleep have a close temporal relationship, our data highlight a possible neuronal interaction between body temperature and sleep regulation.

scholarly journals Drosophila Temperature Preference Rhythms: An Innovative Model to Understand Body Temperature Rhythms

2019 ◽  
Vol 20 (8) ◽  
pp. 1988 ◽  
Author(s):  
Tadahiro Goda ◽  
Fumika N. Hamada
Keyword(s):  
Locomotor Activity ◽  
Body Temperature ◽  
The Body ◽  
Metabolic Energy ◽  
Temperature Preference ◽  
Preferred Temperature ◽  
Activity Rhythms ◽  
Temperature Rhythm ◽  
Body Temperature Rhythm ◽  
Human Body Temperature

Human body temperature increases during wakefulness and decreases during sleep. The body temperature rhythm (BTR) is a robust output of the circadian clock and is fundamental for maintaining homeostasis, such as generating metabolic energy and sleep, as well as entraining peripheral clocks in mammals. However, the mechanisms that regulate BTR are largely unknown. Drosophila are ectotherms, and their body temperatures are close to ambient temperature; therefore, flies select a preferred environmental temperature to set their body temperature. We identified a novel circadian output, the temperature preference rhythm (TPR), in which the preferred temperature in flies increases during the day and decreases at night. TPR, thereby, produces a daily BTR. We found that fly TPR shares many features with mammalian BTR. We demonstrated that diuretic hormone 31 receptor (DH31R) mediates Drosophila TPR and that the closest mouse homolog of DH31R, calcitonin receptor (Calcr), is essential for mice BTR. Importantly, both TPR and BTR are regulated in a distinct manner from locomotor activity rhythms, and neither DH31R nor Calcr regulates locomotor activity rhythms. Our findings suggest that DH31R/Calcr is an ancient and specific mediator of BTR. Thus, understanding fly TPR will provide fundamental insights into the molecular and neural mechanisms that control BTR in mammals.

REGULATION OF THE 24H BODY TEMPERATURE RHYTHM OF WOMEN IN LUTEAL PHASE: ROLE OF GONADAL STEROIDS AND PROSTAGLANDINS

2002 ◽  
Vol 19 (4) ◽  
pp. 721-730 ◽  
Author(s):  
Angelo Cagnacci ◽  
Serenella Arangino ◽  
Federica Tuveri ◽  
Anna Maria Paoletti ◽  
Annibale Volpe
Keyword(s):  
Body Temperature ◽  
Luteal Phase ◽  
Gonadal Steroids ◽  
Temperature Rhythm ◽  
Body Temperature Rhythm

Modification of circadian body temperature rhythm during the luteal menstrual phase: role of melatonin

1996 ◽  
Vol 80 (1) ◽  
pp. 25-29 ◽  
Author(s):  
A. Cagnacci ◽  
R. Soldani ◽  
G. A. Laughlin ◽  
S. S. Yen
Keyword(s):  
Body Temperature ◽  
Core Body Temperature ◽  
Menstrual Phase ◽  
Temperature Rhythm ◽  
Melatonin Administration ◽  
Early Follicular Phase ◽  
Body Temperature Rhythm ◽  
The Mean ◽  
Core Body

In women during early follicular phase (FP), the rise of melatonin at night accounts for 40% of the nocturnal core body temperature (Tc) decline. In seven normal-cycling women, the circadian rhythms of Tc and melatonin of the FP were compared with those of the luteal phase (LP). In addition, in both phases the Tc response to daytime melatonin administration was investigated. Melatonin levels were comparable during the two menstrual phases, but the nocturnal melatonin onset was delayed by 90 min in the LP (P < 0.01). This was accompanied by a delay of the nadir of the Tc circadian rhythm (P < 0.002), a 0.3 degrees C elevation (P < 0.005) of the mean 24-h value, and a 40% blunting (P < 0.002) of the amplitude. This attenuation of circadian Tc in LP women was replicated in two estrogen-treated hypogonadal women by the administration of medroxyprogesterone acetate. The daytime administration of melatonin (2.5 mg) decreased Tc during the FP (P < 0.01) but was ineffective in the LP. Present data indicate that in LP, in association with high progesterone levels, an attenuated and phase-delayed circadian Tc rhythm may, in part, be due to a reduced effect of melatonin.

Role of huddling on the energetic of growth in a newborn altricial mammal

2007 ◽  
Vol 293 (2) ◽  
pp. R867-R876 ◽  
Author(s):  
Caroline Gilbert ◽  
Stéphane Blanc ◽  
Sylvain Giroud ◽  
Marie Trabalon ◽  
Yvon Le Maho ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Temperature ◽  
Early Time ◽  
Total Energy Expenditure ◽  
Energy Partitioning ◽  
Social Strategy ◽  
Temperature Rhythm ◽  
Body Temperature Rhythm ◽  
Temperature Rhythms

Huddling is considered as a social strategy to reduce thermal stress and promote growth in newborn altricial mammals. So far, the role of huddling on the allocation of saved energy has not been quantified nor have the related impacts on body temperature rhythms. To determine the energy partitioning of rabbit pups either raised alone or in groups of eight, four, or two individuals, when thermoregulatory inefficient (TI) and efficient (TE), we first investigated their total energy expenditure and body composition. We then monitored body temperature and activity rhythms to test whether huddling may impact these rhythms, centered on the suckling event. Pups in a group of eight utilized 40% less energy for thermogenesis when TI than did pups alone and 32% less energy when TE. Pups in groups of eight and four had significantly lower thermoregulatory costs in the TI period, whereas pups in groups of two, four, and eight had lower costs during the TE period. Huddling pups could therefore channel the energy saved into processes of growth and accrued more fat mass (on average 4.5 ± 1.4 g) than isolated pups, which lost 0.7 g of fat. Pups in groups of four and eight had a body temperature significantly higher by 0.8°C than pups in groups of two and one when TI, whereas no more differences were noted when the TE period was reached. Moreover, pups alone showed an endogenous circadian body temperature rhythm that differed when compared with that of huddling pups, with no rise before suckling. Thus huddling enables pups to invest the saved energy into growth and to regulate their body temperature to be more competitive during nursing, particularly at the early time when they are TI.

The glycemic index of a mid morning snack modifies the body temperature rhythm

2013 ◽  
Vol 14 ◽  
pp. e242-e243
Author(s):  
J. Belzunce ◽  
C. Noguera ◽  
L. Gené ◽  
R. Rial
Keyword(s):  
Body Temperature ◽  
Glycemic Index ◽  
The Body ◽  
Temperature Rhythm ◽  
Body Temperature Rhythm

Estimation of Circadian Body Temperature Rhythm Based on Heart Rate in Healthy, Ambulatory Subjects

2017 ◽  
Vol 21 (2) ◽  
pp. 407-415 ◽  
Author(s):  
Soo Young Sim ◽  
Kwang Min Joo ◽  
Han Byul Kim ◽  
Seungjin Jang ◽  
Beomoh Kim ◽  
...  
Keyword(s):  
Heart Rate ◽  
Body Temperature ◽  
Temperature Rhythm ◽  
Body Temperature Rhythm

scholarly journals Effects of Resveratrol on Daily Rhythms of Locomotor Activity and Body Temperature in Young and Aged Grey Mouse Lemurs

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Fabien Pifferi ◽  
Alexandre Dal-Pan ◽  
Solène Languille ◽  
Fabienne Aujard
Keyword(s):  
Locomotor Activity ◽  
Body Temperature ◽  
Biological Clock ◽  
The Elderly ◽  
Aged Mouse ◽  
Dark Cycle ◽  
Temperature Rhythm ◽  
Mouse Lemurs ◽  
Body Temperature Rhythm ◽  
Activity Onset

In several species, resveratrol, a polyphenolic compound, activates sirtuin proteins implicated in the regulation of energy balance and biological clock processes. To demonstrate the effect of resveratrol on clock function in an aged primate, young and aged mouse lemurs(Microcebus murinus)were studied over a 4-week dietary supplementation with resveratrol. Spontaneous locomotor activity and daily variations in body temperature were continuously recorded. Reduction in locomotor activity onset and changes in body temperature rhythm in resveratrol-supplemented aged animals suggest an improved synchronisation on the light-dark cycle. Resveratrol could be a good candidate to restore the circadian rhythms in the elderly.

Milking frequency affects the circadian body temperature rhythm in dairy cows

2008 ◽  
Vol 117 (2-3) ◽  
pp. 130-138 ◽  
Author(s):  
P.E. Kendall ◽  
C.B. Tucker ◽  
D.E. Dalley ◽  
D.A. Clark ◽  
J.R. Webster
Keyword(s):  
Body Temperature ◽  
Dairy Cows ◽  
Temperature Rhythm ◽  
Body Temperature Rhythm ◽  
Milking Frequency
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