scholarly journals Insomnia partially mediates the relationship between pathological personality traits and depression: a case-control study

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11061
Author(s):  
Fenglan Chen ◽  
Xiujin Lin ◽  
Yuli Pan ◽  
Xuan Zeng ◽  
Shengjie Zhang ◽  
...  
Keyword(s):  
Borderline Personality ◽  
Mediating Effect ◽  
Personality Pathology ◽  
Antisocial Personality ◽  
Depression Severity ◽  
Chinese Sample ◽  
Personality Score ◽  
Severity Of Depression ◽  
The Impact ◽  
Aggressive Personality

Background and Objective Personality disorders are frequently associated with insomnia and depression, but little is known about the inter-relationships among these variables. Therefore, this study examined these inter-relationships and the possible mediating effect of insomnia on the association between specific personality pathologies and depression severity. Methods There were 138 study participants, including 69 individuals with depression and 69 healthy controls. The main variables were measured by the Hamilton Depression Rating Scale-24 (HAMD-24), Athens Sleep Insomnia Scale (AIS), and the Personality Diagnostic Questionnaire (PDQ-4+). Multivariate linear regression and mediation analysis were conducted. Results With the exception of the antisocial personality score, all the PDQ-4+ scores and AIS scores were significantly higher in the depression group than in the healthy control group (p < 0.001). In the total sample, all personality pathology scores (p < 0.001), except the antisocial personality score, had significant positive correlations with the AIS scores and HAMD-24 scores, and the AIS scores and HAMD-24 scores were positively correlated (r = 0.620, p < 0.001). Regression analysis revealed that borderline personality, passive-aggressive personality, and insomnia positively predicted the severity of depression, after adjusting for sociodemographic covariates, and that insomnia partially mediated the associations of borderline personality and passive-aggressive personality with depression severity. Conclusions Borderline personality, passive-aggressive personality, and insomnia tend to increase the severity of depression, and the effect of borderline and passive-aggressive personality on depression severity may be partially mediated by insomnia. This is the first study to report these findings in a Chinese sample, and they may help researchers to understand the pathways from specific personality pathologies to the psychopathology of depression better, which should be useful for designing interventions to relieve depression severity, as the impact of specific personality pathology and insomnia should be considered.

scholarly journals Assessment of family function impact on depression severity among infertile women attending a teaching hospital in South-South Nigeria

2020 ◽  
Vol 6 (8) ◽  
pp. FSO595
Author(s):  
Alex A Adelosoye ◽  
Olumuyiwa J Fasipe ◽  
Elihu I Medunoye ◽  
Onyekachukwu C Adelosoye ◽  
Elisha O Sunday
Keyword(s):  
Teaching Hospital ◽  
Significant Relationship ◽  
Severe Depression ◽  
Family Dysfunction ◽  
University Teaching ◽  
Depression Severity ◽  
Family Function ◽  
Severity Of Depression ◽  
Husband Support ◽  
The Impact

Aim: Family function and husband support can impact depression severity in women with infertility disorder. The aim of this study was to assess the impact of family function and husband support on depression severity among women with infertility disorder at the fertility clinics of a University Teaching Hospital, South-South, Nigeria. Methodology: A cross-sectional descriptive study was carried out among 341 female respondents attending the University of Benin Teaching Hospital fertility clinics over a 3-month period, using a semistructured interviewer administered questionnaire. Data obtained were analyzed. Result: Respondents mean age was 36 ± 5.3 years. The overall prevalence for depression in this study was 42.5% with a breakdown of 64.2%, 30.4% and 5.4% of these depressed participants having mild, moderate and severe depression, respectively. Family dysfunction had a statistically significant relationship with severity of depression in women with infertility (p < 0.001). A statistically significant relationship was established between poor husband support and the severity of depression (p < 0.001). Conclusion: Depression is highly prevalent among women with infertility disorder, severe depression was associated with family dysfunction. Good family function would reduce the severity of depression.

Impact of painful physical symptoms on depression outcomes in elderly Asian patients

2014 ◽  
Vol 27 (2) ◽  
pp. 305-312 ◽  
Author(s):  
Diego Novick ◽  
William Montgomery ◽  
Jordan Bertsch ◽  
Xiaomei Peng ◽  
Roberto Brugnoli ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Physical Symptom ◽  
Physical Symptoms ◽  
Bivariate Analysis ◽  
Depression Severity ◽  
Linear Regression Models ◽  
Asian Patients ◽  
Severity Of Depression ◽  
Post Hoc ◽  
The Impact

ABSTRACTBackground:Painful physical symptoms (PPS) are prevalent among elderly patients with depression. We describe the impact of PPS on depression outcomes and quality of life (QOL) of elderly Asian patients with major depressive disorder (MDD).Methods:This post hoc analysis of data from a three-month prospective observational study of East Asian MDD in- or out-patients focused on elderly patients aged ≥60 years. Depression severity was evaluated using the Hamilton depression (HAMD-17) and clinical global impression of severity (CGI-S) scales, while QOL was measured using EuroQOL (EQ-5D and EQ-VAS) instruments. PPS were rated using the modified somatic symptom inventory (SSI).Results:At baseline, depression was moderate to severe and 49% of the 146 elderly patients were painful physical symptom positive (PPS+). Bivariate analysis showed significant correlations between PPS and depression severity and QOL at baseline. Linear regression models showed the baseline factor most significantly associated with depression severity at three months was baseline PPS status. PPS+ patients had a mean increase of 2.87 points in their HAMD-17 rating and 0.77 points in their CGI-S score. Response and remission were significantly lower in PPS+ patients; response was 60% and remission was 40% in PPS+ patients while 82% and 66% in painful physical symptom negative (PPS−) patients. QOL at endpoint was lower in PPS+ patients.Conclusions:PPS are common in elderly Asian patients with MDD and negatively influence depression outcomes and QOL. Patients with PPS had lower QOL at baseline, lower response and remission rates, higher severity of depression, and lower QOL after three months of treatment.

The impact of borderline personality pathology on mothers' responses to infant distress.

2011 ◽  
Vol 25 (6) ◽  
pp. 907-918 ◽  
Author(s):  
Elizabeth J. Kiel ◽  
Kim L. Gratz ◽  
Sarah Anne Moore ◽  
Robert D. Latzman ◽  
Matthew T. Tull
Keyword(s):  
Borderline Personality ◽  
Personality Pathology ◽  
Infant Distress ◽  
The Impact

scholarly journals The interaction between monoamine oxidase A (MAOA) and childhood maltreatment as a predictor of personality pathology in females: Emotional reactivity as a potential mediating mechanism

2018 ◽  
Vol 31 (1) ◽  
pp. 361-377 ◽  
Author(s):  
Amy L. Byrd ◽  
Stephen B. Manuck ◽  
Samuel W. Hawes ◽  
Tayler J. Vebares ◽  
Vishwajit Nimgaonkar ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Antisocial Personality Disorder ◽  
Childhood Maltreatment ◽  
Emotional Reactivity ◽  
Borderline Personality ◽  
Monoamine Oxidase A ◽  
Personality Pathology ◽  
Antisocial Personality ◽  
Gene Environment

AbstractResearch consistently demonstrates that common polymorphic variation in monoamine oxidase A (MAOA) moderates the influence of childhood maltreatment on later antisocial behavior, with growing evidence that the “risk” allele (high vs. low activity) differs for females. However, little is known abouthowthis Gene × Environment interaction functions to increase risk, or if this risk pathway is specific to antisocial behavior. Using a prospectively assessed, longitudinal sample of females (n= 2,004), we examined whether changes in emotional reactivity (ER) during adolescence mediated associations between this Gene × Environment and antisocial personality disorder in early adulthood. In addition, we assessed whether this putative risk pathway also conferred risk for borderline personality disorder, a related disorder characterized by high ER. While direct associations between early maltreatment and later personality pathology did not vary by genotype, there was a significant difference in the indirect path via ER during adolescence. Consistent with hypotheses, females with high-activityMAOAgenotype who experienced early maltreatment had greater increases in ER during adolescence, and higher levels of ER predicted both antisocial personality disorderandborderline personality disorder symptom severity. Taken together, findings suggest that the interaction betweenMAOAand early maltreatment places women at risk for a broader range of personality pathology via effects on ER.

The impact of familial personality disorder and alcoholism on the clinical features of depression

1987 ◽  
Vol 2 (3) ◽  
pp. 195-201
Author(s):  
C. VanValkenburg ◽  
S. Lilienfeld ◽  
H.S. Akiskal
Keyword(s):  
Borderline Personality Disorder ◽  
Family History ◽  
Personality Disorder ◽  
Antisocial Personality Disorder ◽  
Borderline Personality ◽  
Antisocial Personality ◽  
Degree Relative ◽  
The Impact ◽  
Disease Family ◽  
Irritable Mood

SummaryWe compared patients with DSD or depression spectrum disease (family history positive for alcoholism or antisocial personality disorder in a first degree relative) to other depressives. DSD patients were likely to be diagnosed as having antisocial or borderline personality disorder, to be alcoholics, amphetamine abusers, or hysterics. They had more chronic depressive features, including hostility and self-pitying, bad-tempered, labile, and irritable mood, and they were nervous, worrisome, immature, overly dependent, and had tempestuous relationships. Their depressions were usually described as “reactive”, but their social outcomes were more likely to be poor.

Silence in the psychotherapy of adolescents with borderline personality pathology.

2020 ◽  
Author(s):  
Ronan Zimmermann ◽  
Lukas Fürer ◽  
Nathalie Schenk ◽  
Julian Koenig ◽  
Volker Roth ◽  
...  
Keyword(s):  
Borderline Personality ◽  
Personality Pathology

Mediating Effect of Organizational Commitment Between Islamic Human Resource Practices and Organizational Performance Among Islamic Banks of Bangladesh

2018 ◽  
Vol 15 (2) ◽  
pp. 54-65
Author(s):  
Bablu Kumar Dhar ◽  
Rosnia Masruki ◽  
Mahazan Mutalib ◽  
Hatem Mohammed Rahouma ◽  
Farid A. Sobhani ◽  
...  
Keyword(s):  
Organizational Commitment ◽  
Organizational Performance ◽  
Human Resource ◽  
Structural Equation ◽  
Stock Exchange ◽  
Reliability And Validity ◽  
Mediating Effect ◽  
Islamic Banks ◽  
Hr Practices ◽  
The Impact

This paper aims at exploring the impact of Islamic human resource (HR) practices on organizational performance though organizational commitment. Data were collected from randomly selected 170 branch managers of six Islamic Banks listed on Dhaka Stock Exchange of Bangladesh. After collecting data, descriptive analysis and structural equation model were done to examine reliability and validity of the model. By analysis, the study finds that Islamic HR practices have more significant impact on organizational performance though organizational commitment rather than the direct effect of Islamic HR practices to organizational performance. The findings of the study advocate that Islamic banks should emphasize more on Islamic HR practices and organizational commitment to uphold their organizational performance.

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