Study provides important evidence about long-term effects on children

2019 ◽  
Vol 31 (5) ◽  
pp. 19-19
Author(s):  
Lucy Bray
Keyword(s):  
Long Term Effects ◽  
Effects On Children ◽  
Important Evidence

scholarly journals PERINATAL OUTCOMES AND LONG-TERM EFFECTS OF FETAL GROWTH RESTRICTION

2012 ◽  
Vol 61 (6) ◽  
pp. 68-75 ◽  
Author(s):  
Natalya Vladimirovna Artymuk ◽  
Aleksey Gennadyevich Trishkin ◽  
Ekaterina Sergeevna Bikmetova
Keyword(s):  
High Risk ◽  
Fetal Growth ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcomes ◽  
Growth Restriction ◽  
Fetal Life ◽  
Long Term Effects ◽  
Intrauterine Growth ◽  
Effects On Children

The article presents a review of sources concerning perinatal outcomes and long-term effects on children and adults born with intrauterine growth restriction (IUGR). Neonates with IUGR are at high risk for morbidity and mortality. The conditions of antenatal fetal life may program the range of unfavorable long-term effects in adulthood. This requires further study of the etiology, pathogenesis, diagnosis, and management of IUGR.

scholarly journals The long-term effects on children and adolescents of a policy providing work supports for low-income parents

2011 ◽  
Vol 30 (4) ◽  
pp. 729-754 ◽  
Author(s):  
Aletha C. Huston ◽  
Anjali E. Gupta ◽  
Jessica Thornton Walker ◽  
Chantelle J. Dowsett ◽  
Sylvia R. Epps ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Low Income ◽  
Long Term Effects ◽  
Effects On Children ◽  
Work Supports

Zentren für Familien: Nationale und internationale Evidenz – ein Resümee aus familienökonomischer Perspektive

2020 ◽  
Vol 69 (8-9) ◽  
pp. 545-560
Author(s):  
C. Katharina Spieß
Keyword(s):  
Social Space ◽  
Evaluation Studies ◽  
Empirical Studies ◽  
Long Term Effects ◽  
Children And Parents ◽  
Child And Youth Welfare ◽  
Effects On Children ◽  
Anglo American ◽  
Further Development

Zusammenfassung Während Kindertageseinrichtungen primär auf Kinder ausgerichtet sind, haben Zentren für Familien die gesamte Familie im Blick. Im Idealfall bilden sie einen Knotenpunkt in einem nachbarschaftlich orientierten Netzwerk. In den letzten Jahren haben entsprechende Ansätze deutschlandweit an Bedeutung gewonnen. Welche empirische Evidenz gibt es für ihre Wirkungen auf Kinder, Eltern und Familien? Dieser Frage widmet sich dieser Beitrag, um der Politik Anhaltspunkte für eine Weiterentwicklung von Angeboten der Kinder- und Jugendhilfe in diese Richtung zu geben. Insbesondere auf der Basis empirischer Studien aus dem anglo-amerikanischen Raum können für Programme, welche Kinder und Eltern adressieren, tatsächlich kurz- bis langfristige Effekte auf Kinder und Eltern nachgewiesen werden. Deutsche Begleitstudien von Zentren für Familien fokussieren dagegen eher auf andere Aspekte der Implementation oder auch der Sozialraumentwicklung. Sie sollten um mehr Wirkungsstudien, welche sich mit den direkten Effekten auf die Entwicklung von Kindern und Familien befassen, ergänzt werden. Abstract: Centres For Families – National And International Evidence While day care centres for children are primarily geared towards children, centres for families focus on the whole family. Ideally, they form a hub in a neighbourhood-oriented network. In recent years, such approaches have gained in importance throughout Germany. What empirical evidence is there for their impact on children, parents and families? This article is dedicated to this question in order to provide policymakers with pointers for the further development of child and youth welfare services. Particularly on the basis of empirical studies from the Anglo-American countries, short to long-term effects on children and parents can be demonstrated when evaluating programs that address children and parents. German evaluation studies on the activities of centres for families tend to focus more on other aspects, such as implementation or social space development. They should be supplemented by studies that are related to the direct effects of these centres on the development of children and families.

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

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