Evaluating Predictive Value of Preoperative Clinical and Imaging Findings on the Short-Term Outcome of Surgery in Patients Undergoing Lower Lumbar Discectomy

ObjectivesTo investigate the tumor volume and its change on short-term outcome in esophageal squamous cell carcinoma (ESCC) patients who underwent definitive radiotherapy or chemoradiotherapy.Methods and MaterialsAll data were retrospectively collected from 418 ESCC patients who received radiotherapy or chemoradiotherapy at our institution between 2015 and 2019. Short-term outcome using the treatment response evaluation was assessed according to the RECIST 1.1. The tumor volume change rate (TVCR) was defined as follows: TVCR = {1 − [gross tumor volume (GTV) at shrinking irradiation field planning)]/(GTV at the initial treatment planning)} ×100%. Chi square test was used to compare the clinic characteristics in different TVCR groups, and the difference between initial GTV (GTVi) and shrinking GTV (GTVs) was compared using Wilcoxon’s sign rank test. Logistic regression analysis and Spearman correlation was performed.ResultsThere was a significant decrease in GTVi compared to GTVs (P < 0.001). In univariate analysis, age, cT-stage, TNM stage, treatment modality, GTVi, and TVCR were associated with short-term outcome (all P< 0.05). In multivariate analysis, gender and TVCR were statistically significant (P = 0.010, <0.001) with short-term outcome, and the combined predictive value of gender and TVCR exceeded that of TVCR (AUC, 0.876 vs 0.855).ConclusionsTVCR could serve to forecast short-term outcome of radiotherapy or chemoradiotherapy in ESCC. It was of great significance to guide the individualized treatment of ESCC.

Download Full-text

Evaluation of Magnetic Resonance Imaging Findings and Short-Term Outcome in Brain Metastatic Tumors after CyberKnife Treatment

International Journal of Medical Physics Clinical Engineering and Radiation Oncology ◽

10.4236/ijmpcero.2016.51010 ◽

2016 ◽

Vol 05 (01) ◽

pp. 96-99

Author(s):

Jiashou Hu ◽

Hongzi Tian ◽

Na Guo ◽

Di Wang ◽

Jinfeng Sun

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Imaging Findings ◽

Resonance Imaging ◽

Short Term ◽

Metastatic Tumors ◽

Term Outcome ◽

Short Term Outcome

Download Full-text

Early Diffusion MR Imaging Findings and Short-Term Outcome in Comatose Patients with Hypoglycemia

American Journal of Neuroradiology ◽

10.3174/ajnr.a2903 ◽

2012 ◽

Vol 33 (5) ◽

pp. 904-909 ◽

Cited By ~ 30

Author(s):

K. Johkura ◽

Y. Nakae ◽

Y. Kudo ◽

T.N. Yoshida ◽

Y. Kuroiwa

Keyword(s):

Mr Imaging ◽

Imaging Findings ◽

Short Term ◽

Term Outcome ◽

Diffusion Mr ◽

Short Term Outcome ◽

Diffusion Mr Imaging

Download Full-text

Increased Serum Soluble Urokinase Plasminogen Activator Receptor Predicts Short-Term Outcome in Patients with Hepatitis B-Related Acute-on-Chronic Liver Failure

Gastroenterology Research and Practice ◽

10.1155/2019/3467690 ◽

2019 ◽

Vol 2019 ◽

pp. 1-9

Author(s):

Zuxiong Huang ◽

Ning Wang ◽

Shuiwen Huang ◽

Yi Chen ◽

Shida Yang ◽

...

Keyword(s):

Hepatitis B ◽

Liver Failure ◽

Predictive Value ◽

Chronic Liver Failure ◽

Short Term ◽

Urokinase Plasminogen Activator Receptor ◽

Term Outcome ◽

Supar Level ◽

Short Term Outcome ◽

Plasminogen Activator Receptor

Aims. Soluble urokinase plasminogen activator receptor (suPAR) reflects the immune activation in circumstances of inflammation and infection. It has been considered as a risk biomarker associated with poor outcome in various low-grade inflammation and infectious diseases. The study is aimed at investigating whether suPAR has a predictive value with short-term survival in patients with hepatitis B-related acute-on-chronic liver failure (HB-ACLF). Methods. Serum suPAR expression was compared among patients with different states of chronic hepatitis B virus infection. Sixty HB-ACLF patients were recruited as the training cohort and followed up for 90 days. Serum suPAR level and the clinical relevance with short-term outcome were investigated. The temporal dynamics of suPAR were evaluated in 50 HB-ACLF patients with available serum sequentially at baseline, week 2 and week 4. Another 167 HB-ACLF patients were enrolled to validate the predictive value of suPAR with respect to the prognosis. Results. Serum suPAR level was significantly increased in HB-ACLF patients compared to non-ACLF patients. In the training set of HB-ACLF, we observed higher suPAR level, INR, MELD score, and more complications in nonsurvivors than survivors. Longitudinal analysis revealed an increased trend of suPAR level in nonsurvivors during week 0 to week 4 and the modest decline in survivors. It showed that the synchronous suPAR level was higher in nonsurvivors at all indicated time points. Elevated suPAR level at baseline was identified as a strong predictor of a 90-day mortality of HB-ACLF patients. It was confirmed suPAR>16.26 ng/ml had a positive predictive value of 72.22% and a negative predictive value of 77.88% for poor outcome in the validation cohort. Conclusions. Serum suPAR level increases significantly in HB-ACLF patients and associated with a 90-day mortality. It suggests that suPAR might be a potential biomarker to predict the prognosis of HB-ACLF patients.

Download Full-text

Commentary on “COVID-19 pneumonia in the emergency department: correlation of initial chest CT findings with short-term outcome”

Journal of Lung Health and Diseases ◽

10.29245/2689-999x/2021/1.1167 ◽

2021 ◽

Vol 5 (1) ◽

pp. 1-2

Author(s):

Camila Silva Barbosa ◽

Hye Ju Lee

Keyword(s):

Emergency Department ◽

Emergency Radiology ◽

Early Recognition ◽

Severe Disease ◽

Chest Ct ◽

Imaging Findings ◽

Short Term ◽

Term Outcome ◽

Short Term Outcome ◽

Ct Findings

On October 15th 2020, the Emergency Radiology Journal published our article entitled “COVID-19 pneumonia in the emergency department: correlation of initial chest CT findings with short-term outcome”, that evaluated clinical, laboratorial and imaging findings of laboratory confirmed COVID-19 patients as predictors of severe disease. In this paper, we will explore the context and significance of the early recognition of the disease severity on patients’ management.

Download Full-text