scholarly journals Correlation of Serum Zinc Levels with Postpartum Depression- A Case- control Study in North Karnataka

2021 ◽  
Author(s):  
MM Kavitha ◽  
Shravya Dharambhat ◽  
Narayan Mutalik ◽  
SH Chandrashekaraya ◽  
SV Kashinakunti
Keyword(s):  
Postpartum Depression ◽  
Postnatal Depression ◽  
Case Control Study ◽  
Mode Of Delivery ◽  
Serum Zinc ◽  
Case Control ◽  
Healthy Controls ◽  
Zinc Levels ◽  
Control Study ◽  
Serum Zinc Levels

Introduction: Pregnancy is an important event in reproductive mother. At the same time it is associated with stress, which exaggerates the depression. Many factors leads to depression, among them nutrient deficiency like zinc, selenium, iron, calcium, folic acid and vitamin B12 plays a major role. Aim: To estimate and compare serum zinc levels in females with postpartum depression subjects and healthy controls. To find the relationship between serum zinc levels and extent of postpartum depression. Materials and Methods: The present study was a hospital- based case-control study, conducted over a period of three months. It included 40 postpartum depression cases and 40 healthy controls. All the participants were subjected to serum zinc levels estimation. Edinburgh Postnatal Depression Scale (EPDS) score was applied. The individuals who scored greater than 10 were taken as cases and those scoring less than 10 were taken as controls. Data was tabulated and results expressed as mean±SD, student’s t-test and Pearson correlation test was applied for correlation. Results: The present study found decreased serum zinc levels in postpartum depression cases compared to controls. It was found serum zinc levels in cases were 21.63±15.73 μg/dL and 54.16±19.72 μg/dL in controls. There was a negative correlation between the severity of postnatal depression and the serum zinc levels. Not only this, but certain risk factors were also identified, such as age of the mother, months of postpartum, mode of delivery, and the education of the mother. Conclusion: Decreased serum zinc levels do indeed correlate to a change in maternal mental health, and then the knowledge would not only help in diagnosis by tests, but also further patient care.

SERUM ZINC LEVELS IN CHILDREN HOSPITALIZED WITH PNEUMONIA: A CASE CONTROL STUDY

2014 ◽  
Vol 1 (12) ◽  
pp. 1553-1558
Author(s):  
Deepthi D ◽  
Shubha Jayaram ◽  
Savitha M R ◽  
Manjunath S N ◽  
Sreenivas N ◽  
...  
Keyword(s):  
Case Control Study ◽  
Serum Zinc ◽  
Case Control ◽  
Zinc Levels ◽  
Control Study ◽  
Serum Zinc Levels

scholarly journals Serum Zinc Levels in Iron Deficient Women: A Case-Control Study

2016 ◽  
Vol 33 (2) ◽  
pp. 156-158 ◽  
Author(s):  
Onur Özhan ◽  
Neslihan Erdem ◽  
İsmet Aydoğdu ◽  
Mehmet Ali Erkurt ◽  
İrfan Kuku
Keyword(s):  
Case Control Study ◽  
Serum Zinc ◽  
Case Control ◽  
Iron Deficient ◽  
Zinc Levels ◽  
Control Study ◽  
Serum Zinc Levels

scholarly journals Serum zinc levels in hospitalized children with pneumonia: a hospital-based case–control study

2019 ◽  
Vol 13 (5) ◽  
pp. 730
Author(s):  
HamadaK Fayed ◽  
AmiraM.M Hamed ◽  
YasserT Kassem ◽  
AhmedM Solaiman
Keyword(s):  
Case Control Study ◽  
Serum Zinc ◽  
Case Control ◽  
Hospitalized Children ◽  
Zinc Levels ◽  
Control Study ◽  
Serum Zinc Levels

Serum Zinc Levels in Hidradenitis Suppurativa: A Case–Control Study

2018 ◽  
Vol 19 (5) ◽  
pp. 771-777 ◽  
Author(s):  
Inés Poveda ◽  
Eva Vilarrasa ◽  
Antonio Martorell ◽  
Francisco Javier García-Martínez ◽  
Juan Manuel Segura ◽  
...  
Keyword(s):  
Hidradenitis Suppurativa ◽  
Case Control Study ◽  
Serum Zinc ◽  
Case Control ◽  
Zinc Levels ◽  
Control Study ◽  
Serum Zinc Levels

Low Serum Zinc Levels and Associated Risk Factors in Hospitalized Patients Receiving Oral or Enteral Nutrition: A Case-Control Study

2020 ◽  
Author(s):  
Cristina G.M. Pereira ◽  
Erely R.S. Santana ◽  
Joane E.R. Ramos ◽  
Heloísa M.B.S. da Silva ◽  
Marco A.P. Nunes ◽  
...  
Keyword(s):  
Risk Factors ◽  
Enteral Nutrition ◽  
Case Control Study ◽  
Serum Zinc ◽  
Case Control ◽  
Zinc Levels ◽  
Associated Risk Factors ◽  
Control Study ◽  
Serum Zinc Levels ◽  
Low Serum

scholarly journals Relationship between serum zinc levels and simple febrile seizures: hospital based case control study

2017 ◽  
Vol 5 (1) ◽  
pp. 42 ◽  
Author(s):  
. Hubaira ◽  
Zubir A. Wani ◽  
Syed Muneeb R. Qadri
Keyword(s):  
Case Control Study ◽  
Adult Life ◽  
Serum Zinc ◽  
Febrile Seizures ◽  
Case Control ◽  
Research Centre ◽  
History Of ◽  
Zinc Levels ◽  
Control Study ◽  
Serum Zinc Levels

Background: Owing to the excessive susceptibility of  the  immature  brain  to temperature, febrile seizures remain one of the common neurological conditions of childhood. Although simple febrile seizures do not pose any increased neurological problems in adult life, but the anxiety, hospitalization and prophylaxis for the episode do call for a genuine concern. A correlation between zinc deficiency and febrile seizures has been proposed and a few studies undertaken have shown mixed conclusions. This case control study was undertaken to compare the serum Zinc levels in patients with simple febrile seizures against the controlled patients with short febrile illness without seizures and to find the correlation if any between simple febrile seizures and serum zinc levels.Methods: The hospital based, observational case control study was done in Batra Hospital and Medical research Centre, New Delhi. A total of 200 children aged 6 months to 6 years admitted in the hospital with history of short pyrexia (fever for 2 days or less) and fulfilling our inclusion criteria were enrolled for the study after taking an informed consent from their attendants and classified into 2 groups of 100 each as cases and controls. Patients with history of simple febrile seizures as cases and those with fever without seizures as controls. A detailed history was taken, and complete physical examination was done on the patients and recorded on a precoded and pretested proforma. The data was analysed on SPSS 17.Results: Our results showed a mean of serum zinc levels in cases as 61.53±15.87 mcg/dl which was found to be lower compared to controls as 71.90+18.50 mcg /dl. Further the difference was found to be statistically significant (P<0.05).Conclusions: Low serum zinc levels in the patients of simple febrile seizures in association with other risk factors may enhance the occurrence of seizures triggered by fever. Thus, a possible correlation exists between the mean serum zinc level and simple febrile seizures.

scholarly journals Serum Copper and Zinc Levels and Risk of Hepatocellular Carcinoma: A 1:1 Matched Case-Control Study

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1397-1397
Author(s):  
Aiping Fang ◽  
Huilian Zhu
Keyword(s):  
Serum Zinc ◽  
Serum Levels ◽  
Case Control ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Copper Zinc ◽  
Matched Case ◽  
Zinc Levels ◽  
Control Study ◽  
Serum Zinc Levels

Abstract Objectives Copper and zinc have been involved in the development of liver cancer in laboratory models, yet data from epidemiological studies are limited. We investigated the association of serum levels of copper and zinc and their ratio with the risk of hepatocellular carcinoma (HCC) in a Chinese population. Methods This is a 1:1 matched case-control study conducted between September 2013 and February 2017. Each case with newly diagnosed HCC from the Guangdong Liver Cancer Cohort (GLCC) was matched to one healthy control from the Guangzhou Nutrition and Health Study by age (±1 years) and sex. Serum copper and zinc levels were quantified using inductively coupled plasma mass spectrometry. Conditional logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for age, sex, body mass index, hepatitis infection, smoking status, alcohol drinking status, diabetes, and chronic inflammation. Serum levels of copper and zinc and their ratio were included in models in tertiles with cutpoints based on the distribution of the control participants. Results A total of 556 case-control pairs were included in this study. Mean (SD) age was 60.3 (7.1) years and 83.8% of the participants were men. HCC cases had significantly higher copper and lower zinc levels, and thus higher copper/zinc, than controls. Higher serum zinc levels were associated with a lower risk of HCC (ORT3 vs T1 = 0.21; 95% CI: 0.07–0.64, P for trend = 0.005). However, there was no association between serum copper levels and HCC risk (ORT3 vs T1 = 1.53; 95% CI: 0.62–3.76, P for trend = 0.375). Higher copper/zinc ratio was associated with increased risk of HCC (ORT3 vs T1 = 3.06; 95% CI: 1.08–8.70, P for trend = 0.049). Conclusions Serum zinc levels were inversely associated with the risk of HCC, suggesting a protective role of zinc in preventing HCC development. Funding Sources This work was supported by the National Natural Science Foundation of China.

scholarly journals SAT0077 CARDIOVASCULAR RISK ASSESSMENT WITH CAROTID ULTRASONOGRAPHY IN ADDITION TO THE TRADITIONAL CARDIOVASCULAR RISK FACTORS IN RHEUMATOID ARTHRITIS PATIENTS: A CASE CONTROL STUDY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 973-973
Author(s):  
R. Gonzalez Mazario ◽  
J. J. Fragio-Gil ◽  
P. Martinez Calabuig ◽  
E. Grau García ◽  
M. De la Rubia Navarro ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Disease Duration ◽  
Case Control Study ◽  
Case Control ◽  
Healthy Controls ◽  
Carotid Ultrasonography ◽  
Control Study

Background:Cardiovascular disease (CV) is the most frequent cause of death in rheumatoid arthritis (RA) patients. It is well known that RA acts as an independent cardiovascular risk factor.Objectives:To assess the CV risk in RA patients using carotid ultrasonography (US) additionally to the traditional CV risk factors.Methods:A prospective transversal case control study was performed, including adult RA patients who fulfilled ACR/EULAR 2010 criteria and healthy controls matched according to CV risk factors. Population over 75 years old, patients with established CV disease and/or chronic kidney failure (from III stage) were excluded. The US evaluator was blinded to the case/control condition and evaluated the presence of plaques and the intima-media thickness. Statistical analysis was performed with R (3.6.1 version) and included a multivariate variance analysis (MANOVA) and a negative binomial regression adjusted by confounding factors (age, sex and CV risk factors).Results:A total of 200 cases and 111 healthy controls were included in the study. Demographical, clinical and US data are exposed in table 1. Not any difference was detected in terms of CV risk factors between the cases and controls. In both groups a relationship between age, BMI and high blood pressure was detected (p<0.001).Table 1.Table 2.RA basal characteristicsDisease duration (years)16,98 (11,38)Erosions (X-Ray of hands/feet)163 (81,5%)Seropositive (RF/anti-CCP)146 (73%)Extra-articular symptoms44 (22%)Intersticial difusse lung disease10 (5%)Rheumatoid nodules14 (7%)Prednisone use103 (51,5%)Median dose of Prednisone last year (mg)2,34 (2,84)sDMARDsMethotrexate104 (52%)Leflunomide29 (14,5%)Hydroxycloroquine9 (4,5%)bDMARDs89 (44,5%) TNFi41 (20,5%) Abatacept15 (7,5%) IL6i22 (11%) RTX11 (5,5%)JAKi26 (13%) Baricitinib11 (5,5%) Tofacitinib15 (7,5%)DAS 28-ESR3,1 (2,3, 3,9)SDAI7,85 (4,04, 13,41)HAQ0,88 (0,22, 1,5)RF (U/mL)51 (15, 164,25)Anti-CCP (U/mL)173 (22, 340)Patients showed higher intima-media (both right and left) thickness compared to controls (p<0.006). Moreover it was also related to the disease duration and DAS28 score (p<0.001). A higher plaque account was noted in cases(p<0.004) and it was also related to the disease duration (p<0.001).Conclusion:RA implies a higher CV risk. Traditional CV risk factors explains only partially the global risk. These findings support that RA acts as an independent cardiovascular risk factor.Disclosure of Interests:None declared

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