Prevalence of Upper Extremity Deep Venous Thrombosis Diagnosed by Color Doppler Duplex Sonography in Cancer Patients With Central Venous Catheters

Central venous catheters are widely used in the care of patients with cancer. Indwelling catheters are associated with upper extremity deep venous thrombosis in some patients, and recognition of this entity is an important aspect of treating patients with malignancies. This article will review the incidence, pathogenesis, clinical presentation, diagnosis, treatment, and prophylaxis of catheter-assocated thrombosis in patients with malignancy. The care of pediatric patients with malignancy and catheter-associated thrombosis will also be addressed.

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Peripherally inserted central venous catheters did not increase the risk of deep venous thrombosis in advanced colorectal cancer and lung cancer patients with bevacizumab

Annals of Oncology ◽

10.1093/annonc/mdy277.005 ◽

2018 ◽

Vol 29 ◽

pp. viii696

Author(s):

M. Qiu ◽

Y. Chen ◽

B.-L. Zhang ◽

X.-Y. Wang

Keyword(s):

Colorectal Cancer ◽

Lung Cancer ◽

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Cancer Patients ◽

Advanced Colorectal Cancer ◽

Central Venous Catheters ◽

Central Venous ◽

Lung Cancer Patients

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UPPER EXTREMITY DEEP VENOUS THROMBOSIS

10.54185/tbem/vol14_iss3/a7 ◽

2021 ◽

Vol 14 (3) ◽

Author(s):

A Venkatesh ◽

V Nanda ◽

B Ramesh

Keyword(s):

Emergency Department ◽

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Upper Extremity ◽

Central Venous Catheters ◽

Central Venous ◽

Vein Thrombosis ◽

Patients With Cancer ◽

Monary Embolism ◽

Deep Vein

Upper extremity deep vein thrombosis (UEDVT) constitutes around 10% of all DVT, and can cause both pul-monary embolism (PE) and post-thrombotic syndrome (PTS) in the arm. The incidence of secondary UED-VT is increasing due to widespread use of central venous catheters in patients with cancer and other chronic diseases. We report a case of 51-year-old female diagnosed with upper extremity deep venous thrombosis in emergency department with no co-morbidities and its successful treatment.

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Catheter-related deep venous thrombosis in children with hemophilia

Blood ◽

10.1182/blood.v98.6.1727 ◽

2001 ◽

Vol 98 (6) ◽

pp. 1727-1731 ◽

Cited By ~ 91

Author(s):

Janna M. Journeycake ◽

Charles T. Quinn ◽

Kim L. Miller ◽

Joy L. Zajac ◽

George R. Buchanan

Keyword(s):

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Central Venous Catheters ◽

Catheter Placement ◽

Central Venous ◽

Radiographic Evidence ◽

Catheter Dysfunction ◽

The Mean ◽

Clinical Problems

Abstract Central venous catheters (CVCs) are a common adjunct to hemophilia therapy, but the risk of CVC-related deep venous thrombosis (DVT) in hemophiliacs is not well defined. In a previous study, 13 patients with CVCs had no radiographic evidence of DVT. However, recent abstracts and case studies demonstrate that DVT does occur. Therefore, this study sought to determine the frequency of DVT in children with hemophilia and long-term CVCs and to correlate venographic findings with clinical features. All hemophilia patients with tunneled subclavian CVCs in place for 12 months or more were candidates for evaluation. Patients were examined for physical signs of DVT and questioned about catheter dysfunction. Contrast venograms were obtained to identify DVT. Fifteen boys with severe hemophilia were evaluated, including 9 from the initially studied group of 13. Eight patients had evidence of DVT, 5 of whom previously had normal venograms. Five of 15 patients had clinical problems related to the CVC, all of whom had DVT. Four of 15 patients had suggestive physical signs; 3 had DVT. The mean duration of catheter placement for all patients was 57.5 months (range, 12-102 months). For patients with DVT, the mean duration was 66.6 ± 7.5 months, compared to 49.5 ± 7.2 months for patients without DVT (P = .06). No patient whose CVC was in place fewer than 48 months had an abnormal venogram. Many hemophilia patients with CVCs develop DVT of the upper venous system, and the risk increases with duration of catheter placement.

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Color Doppler Sonographic Imaging in the Assessment of Upper Extremity Deep Venous Thrombosis

Journal of Diagnostic Medical Sonography ◽

10.1177/875647939000600425 ◽

1990 ◽

Vol 6 (4) ◽

pp. 246-246

Keyword(s):

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Upper Extremity ◽

Color Doppler ◽

Sonographic Imaging

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Upper Extremity Venous Thrombosis in Patients With Cancer With Peripherally Inserted Central Venous Catheters: A Retrospective Analysis of Risk Factors

Journal of Oncology Practice ◽

10.1200/jop.2012.000595 ◽

2013 ◽

Vol 9 (1) ◽

pp. e8-e12 ◽

Cited By ~ 26

Author(s):

Daniel H. Ahn ◽

Henrik Bo Illum ◽

David H. Wang ◽

Anant Sharma ◽

Jonathan E. Dowell

Keyword(s):

Risk Factors ◽

Protective Effect ◽

Venous Thrombosis ◽

Retrospective Analysis ◽

Upper Extremity ◽

Central Venous Catheters ◽

Central Venous ◽

Patients With Cancer ◽

Specific Factors

Specific factors significantly increase the risk of upper extremity venous thrombosis in patients with cancer with PICCs, whereas use of anti-platelet agents seems to have a protective effect against it.

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The Risk of Deep Venous Thrombosis and Sepsis in Cancer Patients Due to PICC Lines.

Blood ◽

10.1182/blood.v104.11.4082.4082 ◽

2004 ◽

Vol 104 (11) ◽

pp. 4082-4082

Author(s):

Lee Lin ◽

Stanley Walker

Keyword(s):

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Cancer Patients ◽

Upper Extremity ◽

Retrospective Chart Review ◽

Small Population ◽

Average Patient ◽

Cancer Types ◽

Picc Line

Abstract Context Upper extremity deep venous thrombosis (DVT) represents 8–10% of total DVT of the limb. Long term central venous catheters represent a major cause of upper extremity DVT, especially in cancer patients. This study looks specifically at the risk posed by peripherally inserted central catheters (PICC). Purpose of the Study: To assess the risk of DVT and sepsis due to PICC lines in cancer patients as compared to non-cancer patients. Furthermore, to assess the risk of PICC line related DVT and sepsis among different cancer types. Design, Setting, and Patients: Retrospective chart review of all 190 patients (representing n=244 procedures) who had undergone a PICC line procedure in Union Memorial Hospital (Baltimore, MD) from August 2003 to December 2003. Based on their medical records, it was determined whether or not the patient had experienced PICC line related sepsis or thrombosis. Cancer as a potential risk factor was included in the information collected. 33 of 190 patients were cancer patients. Average patient age 56.7 years. Results: Preliminary results show that from August 1, 2003 to December 5, 2003, among the non-cancer patients 6 (3.8%) patients with DVT and 6 (3.8%) patients with sepsis were identified. Among the cancer patients, 3 (9.1%) patients with DVT and 3 (9.1%) patients with sepsis were identified. Though cancer patients made up only 17.4% of the patient population, they represented 33.3% of the cases of DVT and sepsis. Conclusion: Cancer patients are at a greater risk of thromboses and sepsis due to PICC lines as compared to non-cancer patients. Cancer patients, therefore, represent a unique population of PICC line patients who may require a different protocol of prophylaxis and complication prevention. While different types of cancers may pose different levels of risk (Sorensen et al), this could not be determined with confidence with the preliminary findings due to the small population evaluated so far. Non-cancer patients Cancer patients DVT 6 3.8% Sepsis 6 3.8% DVT 3 9.1% Sepsis 3 9.1%

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