Determination of Dengue in Pregnancy, Maternal and Fetal Outcome: A Case Series from Zonal Hospital in India

2021 ◽  
pp. 37-43
Author(s):  
Tina Singh ◽  
S. M. Singh ◽  
M. M. Paprikar
Keyword(s):  
Case Series ◽  
Fetal Outcome ◽  
In Pregnancy

scholarly journals ENDOCRINOLOGY IN PREGNANCY: Pheochromocytoma in pregnancy: case series and review of literature

2017 ◽  
Vol 177 (2) ◽  
pp. R49-R58 ◽  
Author(s):  
K van der Weerd ◽  
C van Noord ◽  
M Loeve ◽  
M F C M Knapen ◽  
W Visser ◽  
...  
Keyword(s):  
Early Recognition ◽  
Case Series ◽  
Fetal Outcome ◽  
Fetal Mortality ◽  
Tertiary Referral Hospital ◽  
Common Causes ◽  
Alpha Blockade ◽  
Receptor Blockers ◽  
Dedicated Team ◽  
In Pregnancy

Pheochromocytoma in pregnancy is extremely rare. Early recognition is crucial as antepartum diagnosis can largely decrease maternal and fetal mortality rates. As symptoms of pheochromocytoma are rather similar to those of other far more common causes of hypertension during pregnancy, timely diagnosis is a challenge. In pregnant patients, similar to non-pregnant patients, increased plasma and/or 24-h urine (nor)metanephrine concentrations most reliably confirm the diagnosis of pheochromocytoma. MRI and ultrasound are the only imaging modalities that can be used safely during pregnancy to localize the tumor. During pregnancy, pretreatment consists of alpha blockade as usual. However, dosing of α-adrenergic receptor blockers during pregnancy is a challenge as hypertension must be treated while preserving adequate uteroplacental circulation. When the diagnosis is made within the first 24 weeks of pregnancy, it is generally recommended to remove the tumor in the second trimester, while resection is generally postponed till after delivery when the diagnosis is made in the third trimester and medical pretreatment is sufficient. Both during and after pregnancy, laparoscopic surgery is the preferred approach for resection of the tumor. There is no consensus in literature about the preferred route and timing of delivery. Therefore, in our opinion, decisions should be made on an individual basis by an experienced and dedicated multidisciplinary team. Over the last decades, maternal and fetal prognosis has improved considerably. Further increasing awareness of this rare diagnosis and treatment of these patients by a dedicated team in a tertiary referral hospital are critical factors for optimal maternal and fetal outcome.

scholarly journals Compassionate use of remdesivir in pregnancy: a case series

2021 ◽  
Vol 10 (10) ◽  
pp. 3950
Author(s):  
Jui R. Shah ◽  
Khushali P. Parikh ◽  
Aayushi A. Suthar ◽  
Sushma R. Shah ◽  
Supriya D. Malhotra
Keyword(s):  
Pregnant Women ◽  
Birth Defects ◽  
Treatment Options ◽  
Antiviral Drug ◽  
Case Series ◽  
Fetal Outcome ◽  
Limited Data ◽  
Compassionate Use ◽  
Healthcare Crisis ◽  
In Pregnancy

Coronavirus disease 2019 (COVID-19) has resulted in an unprecedented global healthcare crisis. One special population that poses a challenge is pregnant women with COVID-19. However, there is limited data on treatment options for severe coronavirus disease in pregnancy. Remdesivir, an antiviral drug, is currently being studied as a potential treatment of COVID-19 pneumonia. Nevertheless, pregnant women are also being excluded from various clinical trials for the disease. There are some studies mentioned in the literature which have shown no adverse effects of remdesivir during pregnancy. In this study, we present four serial cases of COVID-19 in pregnant women with moderate to severe symptoms who were treated with remdesivir. All of the them showed positive fetal outcome without any birth defects or malformations. However, further studies are necessary to evaluate the biosafety and effects of remdesivir in pregnant women.

scholarly journals Clinical characteristics, management, maternal and neonatal outcome among seven severe and critically ill pregnant women with COVID-19 pneumonia

2020 ◽  
Vol 3 (2) ◽  
pp. 158-166
Author(s):  
Hazari Komal Sundeep ◽  
Paulose Litty ◽  
Kurien Nimmi ◽  
Mohammad Hozaifah ◽  
A Elgergawi Taghrid Faek ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Clinical Characteristics ◽  
Case Series ◽  
Fetal Outcome ◽  
World Health ◽  
Investigational Therapies ◽  
Serious Disease ◽  
Novel Coronavirus ◽  
Health Organization ◽  
In Pregnancy

Pneumonia caused by the Novel coronavirus disease 2019 (COVID-19) is a highly infectious disease and the ongoing outbreak has been declared as a Pandemic by the World health organization. Pneumonia is a serious disease in pregnancy and requires prompt attention. Viral pneumonia has higher morbidity and mortality compared to bacterial pneumonia in pregnancy. All efforts are well exerted to understand the newly emerged disease features but still some areas are gray. The treatment is primarily supportive with antivirals, steroids, anticoagulation and antibiotics for secondary bacterial infection. Severe cases require intensive care monitoring with oxygen support, mechanical ventilation. Investigational therapies include convalescent plasma, cytokine release inhibitors and other immunomodulatory agents like interferons. The mortality appears driven by the presence of severe Adult Respiratory Syndrome (ARDS) and organs failure. COVID pandemic is a challenging and stressful socio-economic situation with widespread fear of infection, disease and death. In the specialty of obstetrics and gynecology, studies are being conducted to ascertain the manifestation of disease in pregnant women and the fetal outcome. The aim of our case series is to describe the demographics, clinical characteristics, laboratory and radiological findings, feto- maternal outcome of severe and critical COVID pneumonia in pregnant women in Latifa Hospital.

scholarly journals Successful maternal and fetal outcome in a patient with chronic myeloid leukemia on chemotherapy

2020 ◽  
Vol 9 (2) ◽  
pp. 832
Author(s):  
Nishtha Jaiswal ◽  
Harsha Khullar ◽  
Geeta Mediratta ◽  
Sharmistha Garg
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Philadelphia Chromosome ◽  
Myeloproliferative Neoplasm ◽  
Case Series ◽  
Fetal Outcome ◽  
Total Leucocyte Count ◽  
Term Survival ◽  
Drug Of Choice ◽  
In Pregnancy

Chronic myeloid leukemia (CML) is a myeloproliferative-neoplasm accounting for 15% of adult leukemias. Management of leukemia in pregnancy and effect of anti-neoplastic agents on pregnancy outcomes is not well investigated. Management of pregnancy in CML is complicated by the fact that drug used in its treatment i.e. imatinib can lead to teratogenicity in fetus, whereas withholding the drug may lead to relapse of disease. However, pregnancy itself does not alter course of CML. A 19-year-old female, was diagnosed with CML at 15 years of age. She was positive for Philadelphia chromosome. She was on imatinib and had achieved clinical, hematologic and molecular remission. Patient was on regular follow-up till 18 years of age. 45 months post diagnosis she presented with 8 weeks amenorrhoea. Ultrasound (USG) done at 5 weeks gestation showed a single live intrauterine fetus. She took imatinib during this period of organogenesis, so she was advised medical termination of pregnancy (MTP) by treating oncologist. However, patient denied MTP, so her imatinib was stopped and pregnancy continued. The quantitative Bcr/Abl PCR transcript levels at 16, 20 and 28 weeks of gestation were not detectable. The patient did not develop any symptoms or signs suggestive of CML and total leucocyte count remained normal throughout pregnancy. Patient went into preterm-labor at 36 weeks gestation and delivered a healthy male baby weighing 3.1 kg. The baby was well and had a normal examination. USG abdomen of baby was also normal. CML in pregnancy is rare and imatinib is the drug of choice with which long term survival is possible. Imatinib in large case series has been known to be associated with adverse fetal outcomes although evidence to the contrary also exists. Further studies are needed to draw a conclusion on this debatable issue.

scholarly journals Hypertrophic Obstructive Cardiomyopathy and Pregnancy: A Clinical Case Series

2018 ◽  
Vol 03 (02/03) ◽  
pp. 193-197
Author(s):  
Anupama Hari ◽  
Momina Zulfeen ◽  
Sindhu Madhavaneni
Keyword(s):  
Regional Anesthesia ◽  
Clinical Case ◽  
Case Series ◽  
Hypertrophic Obstructive Cardiomyopathy ◽  
Fetal Outcome ◽  
Reproductive Age ◽  
Fetal Demise ◽  
Screening Programs ◽  
High Risk Women ◽  
In Pregnancy

AbstractHypertrophic obstructive cardiomyopathy (HOCM) is a primary myocardial disorder caused by mutations in several different genes coding for contractile proteins. Although HOCM is being increasingly diagnosed in women of reproductive age due to widespread use of echocardiography and screening programs, there are fewer studies of HOCM in pregnancy owing to the rarity of the disease and poor recognition. Our clinical case series includes five cases of hypertrophic cardiomyopathy and its management. The authors describe five women presenting with HOCM with varied symptoms. All patients except one had favorable outcome. Neonatal outcome was good except for a second trimester intrauterine fetal demise. Intensive care unit (ICU) requirement ranged from 5 to 10 days. Two cases were established cases of HOCM. Pain relief was adequate with narcotics, although regional anesthesia was given to one with HOCM with corrected obstruction. No hypotension or deterioration was noted. Although it is believed that HOCM is well tolerated in pregnancy, it is important to have the diagnosis since management differs. Inadvertent regional anesthesia or hypotension due to blood loss or heightened sympathetic response to pain may prove detrimental to these patients. Maternal and fetal outcome are good. Prenatal routine echocardiography screening may prove efficient in identifying high-risk women, for early referral and better management.

scholarly journals Takayasu arteritis in pregnancy: A case series

2020 ◽  
Vol 8 (2) ◽  
pp. 109-113
Author(s):  
Ipsita Mohapatra ◽  
Subha Ranjan Samantaray ◽  
priyanka G ◽  
Vivekananda Achanta
Keyword(s):  
Takayasu Arteritis ◽  
Neonatal Outcome ◽  
Systemic Vasculitis ◽  
Case Series ◽  
Fetal Outcome ◽  
Chronic Inflammatory Disease ◽  
Unknown Etiology ◽  
Primary Systemic Vasculitis ◽  
Sparing Effect ◽  
In Pregnancy

Takayasu arteritis is a disease of unknown etiology which is a primary systemic vasculitis leading to stenotic and occlusive changes. Takayasu arteritis is a chronic inflammatory disease in progressive pattern which chiefly affects the aorta and its main branches. The diagnosis of the disease is mainly based on the clinical suspicion, history, physical examination and vascular imaging. We present here three cases of takayasu arteritis in pregnancy that were treated at our institute in the last 5 years. 1st case had complications like severe preeclampsia, abruption, temporary loss of vision, and intra uterine death of fetus. In 2nd case there was brain sparing effect of fetus, but other than that she did not have any other complications and neonatal outcome was also good without any neonatal complications. In the 3rd case antenatal and postnatal periods were uneventful and with good neonatal outcome. Pregnancy with takayasu arteritis needs to be timely diagnosed and treated for best maternal and fetal outcome.

CASE SERIES: ERCP IN PREGNANCY- CAN WE AVOID RADIATION?

2018 ◽  
Author(s):  
F Rhodes ◽  
S Murray ◽  
R Aguilo ◽  
R Shidrawi
Keyword(s):  
Case Series ◽  
In Pregnancy

TO REVIEW THE TIMING OF INTERVENTION WHICH WILL PROVIDE THE BEST OUTCOME IN HYPOTHYROIDISM IN PREGNANCY

2019 ◽  
Vol 3 (4) ◽  
Author(s):  
Dr. Archana Mohana ◽  
Dr. Sujata Badoniya
Keyword(s):  
Pregnant Women ◽  
Thyroid Disease ◽  
Fetal Outcome ◽  
Thyroxine Therapy ◽  
In Pregnancy

The Aim of this study is to Review the timing of intervention which will provide the Best Outcome in Hypothyroidism in Pregnancy. Hypothyroid pregnant women are appropriately managed with regular antenatal checkup and thyroxine therapy during pregnancy, a good maternal and fetal outcome can be achieved and congenital cretinism and other neuro developmental sequele in the offspring can be averted. Keywords: Intervention, Hyperthyroidism, Pregnancy & Thyroid disease.

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