A Prospective Observational Study on Prevalence and Prognostic Indicators among Tuberculosis and Multidrug Resistance Tuberculosis Patients in Tertiary Care Teaching Hospital

2021 ◽  
pp. 43-48
Author(s):  
A. Noorjahan ◽  
B. Bhargavi ◽  
K. Mallikarjuna ◽  
B. Mohammad Ishaq ◽  
L. Siva Sankar Reddy ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Tertiary Care ◽  
Observational Research ◽  
Prognostic Indicators ◽  
Treatment Result ◽  
High Morbidity ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Number Of Patients ◽  
Mdr Tb

Tuberculosis (TB) is a communicable systemic infectious disease with high morbidity and mortality associated with it. Resistance to medications used to treat tuberculosis has been on the rise in recent years. (multidrug-resistant tuberculosis)  (MDR-TB)  is a significant challenge to (TB) control around the world. An observational research was conducted in a tertiary care teaching hospital to determine the interim pharmacological and microbial results of Rifampicin resistance TB patients. Data from Santhiram Medical College and General Hospital, Nandyal, Kurnool Dist. Andhra Pradesh were obtained from Aug 2020 to Feb 2021, after receiving ethical approval from the Institutional Ethics Committee. The effects of the regimen are determined in terms of cure, finished treatment, treatment failure, number of patients moved to MDR-TB, number of patients who died in long-term MDR-TB regimen patients. Microsoft Excel 2007 was used to analyse the data. There were 82 male and 23 female out of 105 patients included in the study. Of these 75 patients were from rural areas and 40 from urban areas Using the Chi-square test and X2=12.1026, p=0.0005, which was important, the correlation between geographical spread and treatment result was determined. Out of 115 patients, 99 (86.09 percent) were cured of their disease, 06 (5.22 percent) died, 10 (8.69 percent) developed MDR-TB, and 2 (1.74 percent) were deemed medication errors. Males between the ages of 51 and 70 are more vulnerable to TB than females, according to our results. Compared to females of the same age, male patients over 40 years of age are more vulnerable to MDRTB. this was not part of the research objectives, emphasis should not be placed on this as either conclusion or recommendation.

scholarly journals Comparative evaluation of adverse drug reactions in patients of acne prescribed with either topical benzyl peroxide or retinoic acid in a tertiary care teaching hospital

2017 ◽  
Vol 3 (2) ◽  
pp. 228
Author(s):  
Ishan Pandya ◽  
Purna Pandya ◽  
Neha Pethani ◽  
Rima Bharatbhai Shah
Keyword(s):  
Retinoic Acid ◽  
Adverse Events ◽  
Teaching Hospital ◽  
Adverse Drug Events ◽  
Tertiary Care ◽  
Dermatology Department ◽  
Tertiary Care Teaching Hospital ◽  
Male Predominance ◽  
Care Teaching ◽  
Number Of Patients

<p class="abstract"><strong>Background:</strong> To evaluate and compare the profile of adverse drug reaction, its causality, severity and preventability in patients of acne prescribed with either topical benzyl peroxide or topical retinoic acid in a tertiary care teaching hospital.</p><p class="abstract"><strong>Methods:</strong> Two hundred patients attending to dermatology department with acne and prescribed with either topical benzyl peroxide or topical retinoic acid were observed for occurrence of adverse drug events (ADEs). ADEs were either spontaneously reported or elucidated from personal interviews and analyzed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of total 200 patients, 110 (55%) were given benzoyl peroxide gel (2.5%) and remaining 90 (45%) were given retinoic acid cream (0.025%). Total 54 adverse events were reported in 47 (23.5%) patients. Highest number of patients having ADR was from 16-20 years (35, 74.46%) with male predominance (59.57%). Number of adverse events reported was significantly higher (p &lt;0.05) in retinoic acid group (34, 62.96%) as compare to benzyl peroxide group (20, 37.03%). Most common ADRs were exfoliation (14, 25.92%) and burning sensation (13, 24.07%). Most of the ADRs fell in category of ‘probable’ and ‘possible’ in causality assessment by both WHO-UMC method and Narenjo’s scale. All the ADRs were of mild (44, 81.48%) and moderate (10, 18.52%) severity. Majority of ADRs were not preventable (24, 44.44%) followed by definitely preventable 22(40.74%) and 8 (14.81%) probably preventable.</p><p><strong>Conclusions:</strong> ADRs is a common problem associated with topically used medications for acne and its occurrence is significantly higher with retinoic acid as compare to benzyl peroxide. Early diagnosis and proper education about use of topical drugs can prevent some of the ADRs. </p>

scholarly journals Evaluation of used eye drop containers for microbial contamination in outpatient department of tertiary care teaching hospital

2018 ◽  
Vol 7 (5) ◽  
pp. 895
Author(s):  
Narendra P. Bachewar ◽  
Durgesh Deshmukh ◽  
Sachin R. Choudhari ◽  
R. S. Joshi
Keyword(s):  
Teaching Hospital ◽  
Microbial Contamination ◽  
Tertiary Care ◽  
Observational Research ◽  
Eye Drops ◽  
Risk Of Infection ◽  
Tertiary Care Teaching Hospital ◽  
E Coli ◽  
Care Teaching ◽  
Ocular Infections

Background: Contaminated eyedrops are considered as serious risk factor for many iatrogenic ocular infections. Apart from the risk of infection, microbial contamination may alter the pH of the solution thereby reducing the efficacy of drugs. Presently many preservatives are added to these eye drops preparations to extend the duration of use. Hence authors aimed this study to find the contamination rates in such eye drop preparations.Methods: This was a prospective observational research conducted at Ophthalmology OPD, of tertiary care teaching hospital for the period of 2 months. Total fifty five used eyedrops were collected.Results: Authors found that 25.45% of the collected eye drops were contaminated with various organisms, viz. E. coli (10.90%), Staphylococcus aureus (9.09%), Pseudomonas aerugenosa (1.81%), Bacillus subtilis (1.81%) and Candida albicans (1.81%). Among various eyedrops, mydriatic (60%) eyedrops had the highest rate of contamination. We also found that, different preservatives in the eye drops were presents with different level of microbial contamination.Conclusions: The present study showed that there is a definite co-occurrence between eyedrop contamination and ocular infections irrespective of preservatives. This research raises a concern about questionable efficacy of preservatives. 

scholarly journals Retrospective Evaluation of Patients Leaving Against Medical Advice from Intensive Care Unit (ICU) in Tertiary Care Teaching Hospital

2021 ◽  
Vol 6 (1) ◽  
pp. 2-7
Author(s):  
Kiran Adhikari ◽  
Kriti Devkota ◽  
Rajesh Kumar Yadav ◽  
Rakesh Sah
Keyword(s):  
Teaching Hospital ◽  
Tertiary Care ◽  
Medical Advice ◽  
Optimum Level ◽  
Against Medical Advice ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Number Of Patients ◽  
The Mean ◽  
Leaving Against Medical Advice

Introduction: Leaving Against Medical Advice (LAMA) can cause a state of dilemma among the treating physician whether to continue the treatment or to de-escalate from the treatment. It can deteriorate the primary disease of the patient, leading to an increase rate of re-admission to the hospital, increased morbidity and mortality. This is a worldwide phenomenon and the prevalence of LAMA varies between various countries and between different region, religion, and the socioeconomic status of the patient in the same country.Methods: The hospital records from 1st December 2018 to 30th November 2019 of a tertiary care teaching hospital were studied. Patient demography, disease characteristics and length of ICU stay and the factors leading to LAMA were noted and statistically analysed.Results: During the study period, 14.5% of patients asked for LAMA. The mean age was 51.22 ± 22.39 years (range 8 months to 97 years) with Male predominance (n= 288, 62.60%) over Female (n= 172, 37.39%). Patients residing in rural areas were 56.08% (n=258) and 63.91% were financially dependent on others for their living. The mean length of stay in hospital was 3.02 ± 3.50 days while 30.86% of patients required mechanical ventilation. About 51.73% of patients taking LAMA were admitted from the Internal medicine department. Around 79.56% were Hindus, with 54.34% opting for LAMA due to financial restrain followed by poor prognosis (22.60 %).Conclusion: The large number of patients admitted in ICU opts out for LAMA. This necessitates formulation and implementation of strategies to reduce the prevalence of LAMA discharge so that patient gets the optimum level of care and the burden in the health care system is reduced

Congenital Anomalies Among Singleton Live Births in a Tertiary Care Teaching Hospital

2011 ◽  
Vol 3 (11) ◽  
pp. 358-360
Author(s):  
Manikanta Reddy. V Manikanta Reddy. V ◽  
◽  
Senthil Kumar. S Senthil Kumar. S ◽  
Sanjeeva Reddy. N Sanjeeva Reddy. N
Keyword(s):  
Teaching Hospital ◽  
Congenital Anomalies ◽  
Tertiary Care ◽  
Tertiary Care Teaching Hospital ◽  
Live Births ◽  
Care Teaching
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