scholarly journals Comparative Clinical Trial on Aragwadha Erand and Trivrutta Eranda Nitya Virechana in Gridhrasi (Lumbago Sciatica Syndrome): A Study Protocol

Author(s):  
Shweta Parwe ◽  
Sandip Jadhav ◽  
Milind Nisargandha

Background: At present, the life style is gradually shifting away from healthy living, and therefore people fall victim of various diseases. Sedentary lifestyle, stress, improper posture, continuous jerky movements, long travelling, etc., put maximum pressure on the spine and lower portion of the pelvis. About 80–90% of people get affected by low back pain and 5% of those become victims of sciatica. Aim: Studying the effect of Trivrut Eranda Tailam and Aragvadha Eranda Tailam Virechana in Gridhrasi (Lumbago sciatica syndrome). Objectives: To study the effect of Trivrut Eranda Tailam in Gridhrasi, To study the effect of Aragvadha Eranda Tailam in Gridhrasi and to compare the effect of Trivrutta Eranda Tailam and Aragavadha Eranda Tailam in Gridhrasi. Methodology: This study will be a Randomized controlled interventional trial to be conducted on 30 participants. The participants will be divided into two groups viz. Group A and Group B. The patient in Group A will be given Trivrutt Eranda Tailam (15 patients) and Group B will be given Aragvadha Eranda Tailam (15 patients). Results: Nitya virechan will be carried out in both these groups. The results will be compared on the basis of SLR test [Straight leg raising test], Lassegue sign, Flip test, Bowstring test and Serum electrolytes used for Gridhrasi. Conclusion: Conclusions will be drawn on the result.

Author(s):  
Zulekha Saleem ◽  
Amna Aamir Khan ◽  
Sumaira Imran Farooqui ◽  
Rehana Yasmeen ◽  
Jaza Rizvi

Objective: This study aimed to emphasize facilitation training and strengthening of abdominal and core muscles in improving the inter-recti distance (IRD) and associated low back pain (LBP) among young postpartum females. Materials and methods: A single-blinded randomized controlled trial, among forty young postpartum females, was conducted at a community health center. The females were divided into two equal groups through the envelope method where Group A received abdominal crunch training protocol whereas group B received double straight leg raise (DSLR) exercise protocol for 6 weeks and pre and post IRD and Oswestry disability index (ODI) scores were recorded. Results: Group A showed improvement in IRD with a mean difference of 1.95±0.4 whereas in group B it was found to be 2.85±0.35 when assessed through finger palpation method.  The mean difference of IRD, when measured through digital nylon caliper method in abdominal crunch and DSLR exercise group was 4.06±0.74 and 1.2±0.49 respectively. Moreover, ODI scores of group A were 2.70±1.05 whereas, group B scores were found to be 1.1±0.06 showing that LBP reduced in participants who performed abdominal crunch exercise. Conclusion: This study reveals that 6 weeks of exercise protocol was observed to be effective in the management of DRA. Thus, abdominal crunch exercise seemed to produce promising results in a reduction of IRD and associated LBP.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Bing-xin Kang ◽  
Hui Xu ◽  
Chen-xin Gao ◽  
Sheng Zhong ◽  
Jing Zhang ◽  
...  

Abstract Background We aimed to determine the efficacy and safety of multiple doses of intravenous tranexamic acid (IV-TXA) on perioperative blood loss in patients with rheumatoid arthritis (RA) who had undergone primary unilateral total knee arthroplasty (TKA). Methods For this single-center, single-blind randomized controlled clinical trial, 10 male and 87 female participants with RA, aged 50–75 years, who underwent unilateral primary TKA were recruited. The patients received one dose of 1 g IV-TXA 10 min before skin incision, followed by articular injection of 1.5 g tranexamic acid after cavity suture during the surgery. The patients were randomly assigned (1:1) into two groups and received an additional single dose of IV-TXA (1 g) for 3 h (group A) or three doses of IV-TXA (1 g) for 3, 6, and 12 h (group B) postoperatively. Primary outcomes were total blood loss (TBL), hidden blood loss (HBL), and maximum hemoglobin (Hb) level decrease. Secondary outcomes were transfusion rate and D-dimer levels. All parameters were measured postoperatively during inpatient hospital stay. Results The mean TBL, HBL, and maximum Hb level decrease in group B (506.1 ± 227.0 mL, 471.6 ± 224.0 mL, and 17.5 ± 7.7 g/L, respectively) were significantly lower than those in group A (608.8 ± 244.8 mL, P = 0.035; 574.0 ± 242.3 mL, P = 0.033; and 23.42 ± 9.2 g/L, P = 0.001, respectively). No episode of transfusion occurred. The D-dimer level was lower in group B than in group A on postoperative day 1 (P <  0.001), and the incidence of thromboembolic events was similar between the groups (P > 0.05). Conclusion In patients with RA, three doses of postoperative IV-TXA further facilitated HBL and Hb level decrease without increasing the incidence of adverse events in a short period after TKA. Trial registration The trial was registered in the Chinese Clinical Trial Registry (ChiCTR1900025013).


2021 ◽  
Vol 15 (11) ◽  
pp. 3219-3221
Author(s):  
Maryam Liaquat ◽  
Wajida Perveen ◽  
Danish Hassan ◽  
Misbah Amanat Ali ◽  
Muhammad Akhtar ◽  
...  

Lower back pain is one of the most common problems in adults all over the world, and chances of having back pain increases with the age. Objectives: To determine the effect of tailored motor control rehabilitation versus standard exercise program in chronic nonspecific lower back pain. Study Design: Non randomized clinical study. Methodology: A non randomized clinical study was conducted in six-month during 2018 after ethical approval. 40 patients were enrolled through non-probability purposive sampling technique and allocated into two groups (Group A & B). Informed consent was obtained. Individuals between twenty to forty years with chronic nonspecific low back pain with intensity at least 3 on a 10cm visual analog scale (VAS) were included and individuals with past history of trauma of the spine and hip and with any red flags were excluded. Outcomes were measures by Modified Oswestry Disability Index (MODI) and Visual Analogue Scale (VAS). Statistical analysis: Data was analyzed by SPSS software, version 19 as qualitative variables were expressed as mean ± SD. Independent sample T test was also applied. Results: The mean age Group A was 29.05±8.58 and Group B, was 32.05±6.53 years. The result shows that there was a significant difference in outcomes among tailored motorcontrol rehabilitation (Group A) and standard exercise program (Group B). Conclusion: We concluded that motor control rehabilitation was more effective than standard exercise program in decreasing low back pain and improving quality of life. Key Words: Low Back Pain, Tailored Motor Control Rehabilitation, Standard Exercise Program and Modified Oswastry Disability Index.


Author(s):  
Bijal Majiwala ◽  
Trupti Warude ◽  
Amrutkuvar Pawar

Objective: To compare the effects of isometric (stability) and isotonic training on core muscle in patients with non-specific low back pain on pain, endurance, and functional disability.Methods: Forty participants of both genders aged between 20 and 35 years suffering from non-specific low back pain were taken and equally divided into two groups: Group A isometric exercise and Group B isotonic exercise, both the group received baseline treatment of transcutaneous electrical nerve stimulation and hot moist pack. Outcomes measure visual analog scale, endurance test, and modified Oswestry disability index were used the pre-treatment and at the end of 4 weeks.Results: Experiment of both the groups showed a non-significant improvement in pain, endurance, and functional disability. Except for extensor endurance test which shows significant different in Group A.Conclusion: Both isometric and isotonic exercises are equally effective in reducing pain, increase endurance, and improve functional disability in patients with non-specific low back pain.


Author(s):  
Jay Kumar Soni ◽  
Edrish Contractor

Aims: Non specific Low back pain is defined as pain without any known pathology which affects almost all the leading occupation where body's awkward posture, twisting and stress forces are commonly encountered across the globe and it is highly prevalent 60% to 70% in a year. Studies have shown various exercise regimen individual effect on the same but superiority of regimen out of these is not clear. Study Design: Comparative Study Place and Duration of Study: Ahmedabad Institute of Medical Sciences, Duration 2013-15 Objective: To assess and compare the effect of core stability exercise, back school program and Swiss ball exercise on Pain, core endurance and Functional disability. Methodology: A group of 24 patients having non-specific low back pain between age groups 18-40 were randomly selected and allocated in to two groups. Group A(n=12) received traditional exercise whereas Swiss ball exercise was given to Group B(n=12). The subjects were treated for two weeks. Baseline data for VAS, Core endurance and MODI were taken on day1 and at the end of two weeks Result: The results were analyzed by wilcoxon signed rank test within both groups. Both groups showed significant improvement in VAS, core endurance and MODI at the end of 2weeks.Comparison between both the Group A and Group B was done by Mann- whitney U test and statistically no significant difference was seen in VAS, core endurance and MODI between the groups Conclusion: The study concluded that both the exercises are equally effective in reducing pain intensity, improves core endurance and functional status in subjects with non specific low back pain


2012 ◽  
Vol 1 (1) ◽  
pp. 23-27
Author(s):  
Syed Abid Mehdi Kazmi ◽  
Nabiha Mujahid Faruq ◽  
Sumaira Imran Farooqui ◽  
Jharna Devi

OBJECTIVES To assess the effectiveness of lumbar manipulation (high velocity low amplitude) for the treatment of low back pain in comparison to back stretching exercises. Randomized Control Trial (Experimental Study) The study was conducted on 200 patients at the Physiotherapy Department of Ziauddin Hospital among patients with history of low back pain of acute, sub acute or chronic origin. In this study, patients were divided into two groups, group A and group B equally. Group A of 100 patients received Lumbar Manipulation (High Velocity Low Amplitude) and at the same time Group B of 100 patients were treated by back stretching exercises. A pre tested and structured questionnaire was used to collect data. Data was entered and analyzed by using SPSS. Pain was measured on Visual Analogue Scale before and after the given treatment. The study showed significant results for both the interventions in the treatment of low back pain but Lumbar Manipulation has been more effective in different types of low back pain while stretching exercises are less effective. On the basis of this study, we are very confident that lumbar manipulation is more effective for the treatment of low back pain compared to back stretching


Author(s):  
VINEELA KARTHIK NAGURI ◽  
RAVI BABU KOMARAM ◽  
TAMILISETTI VIDYA SAGAR

Objective: The objective of the study was to assess and compare the efficacy and tolerability of flupirtine versus tramadol in patients with chronic moderate low back pain (LBP). Materials and Methods: A prospective study was conducted in the outpatient department of orthopaedics at tertiary care hospital, Rajamahendravarm. After meeting the inclusion criteria, a total of 60 patients were randomly allocated to tablet flupirtine 100 mg in Group A and tablet tramadol 50 mg in Group B. The efficacy of the study drugs was assessed at baseline and the end of treatment by numerical rating scale11, visual analog scale-100 mm, physician’s, and patient’s global assessment. Statistical analysis was done using paired and unpaired t-test and data were presented as mean±standard deviation. Adverse drug reactions were monitored during the treatment. Results: The study results showed that 90% of the patients in Group A and 78% of the patients in Group B had shown a good response to their respective drugs. 30% of flupirtine group patients reported adverse drug reactions which were mild. Conclusion: Both the drugs are effective in the treatment of moderate chronic LBP, but the advantage of flupirtine was, the incidence of adverse drug reactions was less when compared to tramadol group.


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