scholarly journals EFFICACY AND TOLERABILITY OF FLUPIRTINE VERSUS TRAMADOL IN THE TREATMENT OF MODERATE CHRONIC LOW BACK PAIN

Author(s):  
VINEELA KARTHIK NAGURI ◽  
RAVI BABU KOMARAM ◽  
TAMILISETTI VIDYA SAGAR

Objective: The objective of the study was to assess and compare the efficacy and tolerability of flupirtine versus tramadol in patients with chronic moderate low back pain (LBP). Materials and Methods: A prospective study was conducted in the outpatient department of orthopaedics at tertiary care hospital, Rajamahendravarm. After meeting the inclusion criteria, a total of 60 patients were randomly allocated to tablet flupirtine 100 mg in Group A and tablet tramadol 50 mg in Group B. The efficacy of the study drugs was assessed at baseline and the end of treatment by numerical rating scale11, visual analog scale-100 mm, physician’s, and patient’s global assessment. Statistical analysis was done using paired and unpaired t-test and data were presented as mean±standard deviation. Adverse drug reactions were monitored during the treatment. Results: The study results showed that 90% of the patients in Group A and 78% of the patients in Group B had shown a good response to their respective drugs. 30% of flupirtine group patients reported adverse drug reactions which were mild. Conclusion: Both the drugs are effective in the treatment of moderate chronic LBP, but the advantage of flupirtine was, the incidence of adverse drug reactions was less when compared to tramadol group.

Author(s):  
H. Rathi ◽  
P. Rathi ◽  
M. Biyani

Background. Use of Hydroxychloroquine with or without Azithromycin is repurposed in SARS-CoV-2 in the absence of definitive treatment. Objective. To evaluate the association between the use of Hydroxychloroquine and Azithromycin when given alone or in combination on clinical outcomes and adverse drug reactions among lab confirmed SARS CoV-2 positive patients admitted in a COVID tertiary care hospital of a University Medical college. Methods. a retrospective observational comparative study was conducted. COVID-19 positive patients admitted in study hospital for management of COVID-19 were enrolled into the study. The patients were categorized into 4 treatment groups based on having received the following treatment during hospitalization: (A) Hydroxychloroquine with Azithromycin, (B) Hydroxychloroquine without Azithromycin (Hydroxychloroquine alone), (C) Azithromycin alone, and (D) Neither drug, defined as no receipt of either Hydroxychloroquine or Azithromycin in the record; other medications may have been dispensed. Results. 800 patients were enrolled. Mean±Standard deviation of duration of hospital stay (in days) for study Group A was 11.37±7.11, for Group B was 8.37±4.77, for Group C was 18.22 ± 5.69 and for Group D was 6.12±2.97. Mortality in Group A was 29.74%, Group B – 33.16%, Group C – 0% and in Group D – 1.32%. Conclusion. Among hospitalized patients with COVID-19 treatment, Group C was associated with good clinical outcome. However, the interpretation of these findings may be limited by the observational design.


2013 ◽  
Vol 2 (2) ◽  
pp. 10-14
Author(s):  
Samreen Yasmeen ◽  
Syeda Amool Sakeena Rizvi

Acute back pain is the fifth most common reason for visiting the physicians and practitioners. It is one of the most common musculoskeletal problems in the society. This research has been conducted on experimental method by using sample size of 60 patients including both the genders. The participants have been selected from the OPD of physical therapy and rehabilitation of the tertiary care hospital. 60 patients was divided into two groups where Group A was treated with hot packs at low back for 25 minutes with low back strengthening exercises and whereas Group B was treated with SWD (continuous mode) for 15 minutes with the exercises. Exercises were started from the 4th day of treatment in both conditions after being relieved from acute back pain and spasm. Both groups received 5 sessions per week for consecutive 3 weeks. Therefore, the symptoms have been reassessed at 8th and 15th day of treatment. After analyzing the data it was found that, the patients in group A treated with hot packs and back strengthening exercises were relieved from pain more quickly and efficiently than the group B treated with short wave and exercises.


2021 ◽  
Vol 15 (11) ◽  
pp. 3219-3221
Author(s):  
Maryam Liaquat ◽  
Wajida Perveen ◽  
Danish Hassan ◽  
Misbah Amanat Ali ◽  
Muhammad Akhtar ◽  
...  

Lower back pain is one of the most common problems in adults all over the world, and chances of having back pain increases with the age. Objectives: To determine the effect of tailored motor control rehabilitation versus standard exercise program in chronic nonspecific lower back pain. Study Design: Non randomized clinical study. Methodology: A non randomized clinical study was conducted in six-month during 2018 after ethical approval. 40 patients were enrolled through non-probability purposive sampling technique and allocated into two groups (Group A & B). Informed consent was obtained. Individuals between twenty to forty years with chronic nonspecific low back pain with intensity at least 3 on a 10cm visual analog scale (VAS) were included and individuals with past history of trauma of the spine and hip and with any red flags were excluded. Outcomes were measures by Modified Oswestry Disability Index (MODI) and Visual Analogue Scale (VAS). Statistical analysis: Data was analyzed by SPSS software, version 19 as qualitative variables were expressed as mean ± SD. Independent sample T test was also applied. Results: The mean age Group A was 29.05±8.58 and Group B, was 32.05±6.53 years. The result shows that there was a significant difference in outcomes among tailored motorcontrol rehabilitation (Group A) and standard exercise program (Group B). Conclusion: We concluded that motor control rehabilitation was more effective than standard exercise program in decreasing low back pain and improving quality of life. Key Words: Low Back Pain, Tailored Motor Control Rehabilitation, Standard Exercise Program and Modified Oswastry Disability Index.


Author(s):  
Bijal Majiwala ◽  
Trupti Warude ◽  
Amrutkuvar Pawar

Objective: To compare the effects of isometric (stability) and isotonic training on core muscle in patients with non-specific low back pain on pain, endurance, and functional disability.Methods: Forty participants of both genders aged between 20 and 35 years suffering from non-specific low back pain were taken and equally divided into two groups: Group A isometric exercise and Group B isotonic exercise, both the group received baseline treatment of transcutaneous electrical nerve stimulation and hot moist pack. Outcomes measure visual analog scale, endurance test, and modified Oswestry disability index were used the pre-treatment and at the end of 4 weeks.Results: Experiment of both the groups showed a non-significant improvement in pain, endurance, and functional disability. Except for extensor endurance test which shows significant different in Group A.Conclusion: Both isometric and isotonic exercises are equally effective in reducing pain, increase endurance, and improve functional disability in patients with non-specific low back pain.


Author(s):  
Jay Kumar Soni ◽  
Edrish Contractor

Aims: Non specific Low back pain is defined as pain without any known pathology which affects almost all the leading occupation where body's awkward posture, twisting and stress forces are commonly encountered across the globe and it is highly prevalent 60% to 70% in a year. Studies have shown various exercise regimen individual effect on the same but superiority of regimen out of these is not clear. Study Design: Comparative Study Place and Duration of Study: Ahmedabad Institute of Medical Sciences, Duration 2013-15 Objective: To assess and compare the effect of core stability exercise, back school program and Swiss ball exercise on Pain, core endurance and Functional disability. Methodology: A group of 24 patients having non-specific low back pain between age groups 18-40 were randomly selected and allocated in to two groups. Group A(n=12) received traditional exercise whereas Swiss ball exercise was given to Group B(n=12). The subjects were treated for two weeks. Baseline data for VAS, Core endurance and MODI were taken on day1 and at the end of two weeks Result: The results were analyzed by wilcoxon signed rank test within both groups. Both groups showed significant improvement in VAS, core endurance and MODI at the end of 2weeks.Comparison between both the Group A and Group B was done by Mann- whitney U test and statistically no significant difference was seen in VAS, core endurance and MODI between the groups Conclusion: The study concluded that both the exercises are equally effective in reducing pain intensity, improves core endurance and functional status in subjects with non specific low back pain


Cureus ◽  
2020 ◽  
Author(s):  
Mukesh Kumar ◽  
Masroor Ahmed ◽  
Ghulam Hussain ◽  
Muhammad Bux ◽  
Naveed Ahmed ◽  
...  

2012 ◽  
Vol 1 (1) ◽  
pp. 23-27
Author(s):  
Syed Abid Mehdi Kazmi ◽  
Nabiha Mujahid Faruq ◽  
Sumaira Imran Farooqui ◽  
Jharna Devi

OBJECTIVES To assess the effectiveness of lumbar manipulation (high velocity low amplitude) for the treatment of low back pain in comparison to back stretching exercises. Randomized Control Trial (Experimental Study) The study was conducted on 200 patients at the Physiotherapy Department of Ziauddin Hospital among patients with history of low back pain of acute, sub acute or chronic origin. In this study, patients were divided into two groups, group A and group B equally. Group A of 100 patients received Lumbar Manipulation (High Velocity Low Amplitude) and at the same time Group B of 100 patients were treated by back stretching exercises. A pre tested and structured questionnaire was used to collect data. Data was entered and analyzed by using SPSS. Pain was measured on Visual Analogue Scale before and after the given treatment. The study showed significant results for both the interventions in the treatment of low back pain but Lumbar Manipulation has been more effective in different types of low back pain while stretching exercises are less effective. On the basis of this study, we are very confident that lumbar manipulation is more effective for the treatment of low back pain compared to back stretching


2012 ◽  
Vol 7 (2) ◽  
pp. 29-32
Author(s):  
B Ahmed ◽  
S Alam ◽  
I Rashid ◽  
N Rahman ◽  
A Rahman ◽  
...  

Background: Acute low back pain (LBP) affects a significant proportion of the population. Transcutaneous electrical nerve stimulation (TENS) was introduced more than 30 years ago as an adjunct to the pharmacological management of pain. However, despite its widespread use, the usefulness of TENS in LBP is still controversial. Introduction: LBP is a common problem in Bangladesh. Acute LBP is usually defined by a period of complaints of LBP of six weeks or shorter. TENS may improve acute LBP. Objective: To evaluate the effectiveness of TENS on acute LBP and also to ensure the patients wellbeing by shortening recovery time who have acute LBP. Methods: A prospective study was carried out in the Department of Physical Medicine and Rehabilitation, Bangubandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from July 2008 to December 2008. The patients were divided into two groups (A and B). Patients of Group A (30 patients) were treated with TENS, Non-steroidal anti-inflammatory drugs (NSAIDs) and activities of daily living (ADLs) instruction. Patients of group B (28 patients) were treated with NSAIDs and ADLs instructions. Results: A total of 58 Patients of acute LBP were included in this study. The mean age of the patients was 38.5 ± 9.01 years. Main causes of pain were muscle strain (39.65%), nonspecific LBP (22.41%), prolapsed lumber intervertebral disc (17.24%), lumbar spondylosis (13.79%) and sciatica (6.91%). After treatment the result was compared and student's 't' test was done to see the level of significance. Method was found significant after treatment (p<0.05). Twenty four (80%) patients were improved in group A and 18 (64.28%) patients in group B. Patient compliances of group A were better than that in group B. Conclusion: Effect of TENS on patients with acute low back pain is beneficial. DOI: http://dx.doi.org/10.3329/jafmc.v7i2.10393 JAFMC 2011; 7(2): 29-32


Author(s):  
Rishabh Gupta ◽  
Shavi Mahajan ◽  
Deepika Dewan ◽  
Rajat Gupta

Background: Backache is a national, personal and clinical problem. It is experienced by most of the population at some time and is a drain on the nation’s resources. Personally, it is distressing because it can remain a major unresolved dilemma and clinically it poses challenges in diagnosis and treatment.Methods: The present cross sectional study was conducted among 200 patients presenting with chronic low back pain, in the OPD of Post Graduate Department of Orthopaedics, Govt. Medical College, Jammu over a period of one year from November 2006 to October 2007.Results: The average age of patients was 38.39 years with slight male predominance. Majority of the patients were non-sedentary workers. In majority of the cases (58%), duration of low backache was from 3 months to 1 year with the average of 25.8 months (2.158 years). The commonest mode of presentation was low back pain with radiation to lower limbs. Seasonal variation in the intensity of pain was observed in 50% of the cases. Tenderness of the spine was the commonest physical sign. Disc degenerative disease was found to be commonest cause of low backache, being present in 72% of the cases.Conclusions: Low back pain is common in 3rd and 4th decade of life. The commonest mode of presentation was low back pain with radiation to lower limbs. Disc degenerative disease was found to be commonest cause of low backache, being present in 72% of the cases.


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