scholarly journals Blood Flow Imaging Using 4D Flow MRI and Clinical Application in Fontan Circulation

2018 ◽  
Vol 34 (4) ◽  
pp. 205-206
Author(s):  
Jun Maeda
Keyword(s):  
Blood Flow ◽  
Clinical Application ◽  
Fontan Circulation ◽  
Flow Imaging ◽  
4D Flow Mri ◽  
4D Flow ◽  
Blood Flow Imaging ◽  
Flow Mri

scholarly journals Associations between haemodynamics and wall enhancement of intracranial aneurysm

2021 ◽  
pp. svn-2020-000636
Author(s):  
Miaoqi Zhang ◽  
Fei Peng ◽  
Xin Tong ◽  
Xin Feng ◽  
Yunduo Li ◽  
...  
Keyword(s):  
Blood Flow ◽  
High Resolution ◽  
Ordinal Regression ◽  
Parent Artery ◽  
Black Blood ◽  
4D Flow Mri ◽  
4D Flow ◽  
Unruptured Intracranial Aneurysms ◽  
Black Blood Mri ◽  
Flow Mri

Background and purposePrevious studies have reported about inflammation processes (IPs) that play important roles in aneurysm formation and rupture, which could be driven by blood flow. IPs can be identified using aneurysmal wall enhancement (AWE) on high-resolution black-blood MRI (BB-MRI) and blood flow haemodynamics can be demonstrated by four-dimensional-flow MRI (4D-flow MRI). Thus, this study investigated the associations between AWE and haemodynamics in unruptured intracranial aneurysms (IA) by combining 4D-flow MRI and high-resolution BB-MRI.Materials and methodsBetween April 2014 and October 2017, 48 patients with 49 unruptured IA who underwent both 4D-flow MRI and high-resolution BB-MRI were retrospectively included in this study. The haemodynamic parameters demonstrated using 4D-flow MRI were compared between different AWE patterns using the Kruskal-Wallis test and ordinal regression.ResultsThe results of Kruskal-Wallis test showed that the average wall shear stress in the IA (WSSavg-IA), maximum through-plane velocity in the adjacent parent artery, inflow jet patterns and the average vorticity in IA (vorticityavg-IA) were significantly associated with the AWE patterns. Ordinal regression analysis identified WSSavg-IA (p=0.002) and vorticityavg-IA (p=0.033) as independent predictors of AWE patterns.ConclusionA low WSS and low average vorticity were independently associated with a high AWE grade for IAs larger than 4 mm. Therefore, WSS and average vorticity could predict AWE and circumferential AWE.

scholarly journals A pilot study investigating the use of 4D flow MRI for the assessment of splanchnic flow in patients suspected of mesenteric ischaemia

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pauline Hall Barrientos ◽  
Katrina Knight ◽  
Douglas Black ◽  
Alexander Vesey ◽  
Giles Roditi
Keyword(s):  
Blood Flow ◽  
Pilot Study ◽  
Splenic Vein ◽  
Normal Subjects ◽  
Mesenteric Ischaemia ◽  
4D Flow Mri ◽  
4D Flow ◽  
Flow Mri ◽  
Mesenteric Vessels ◽  
Flow Changes

AbstractThe most common cause of chronic mesenteric ischaemia is atherosclerosis which results in limitation of blood flow to the gastrointestinal tract. This pilot study aimed to evaluate 4D flow MRI as a potential tool for the analysis of blood flow changes post-prandial within the mesenteric vessels. The mesenteric vessels of twelve people were scanned; patients and healthy volunteers. A baseline MRI scan was performed after 6 h of fasting followed by a post-meal scan. Two 4D flow datasets were acquired, over the superior mesenteric artery (SMA) and the main portal venous vessels. Standard 2D time-resolved PC-MRI slices were also obtained across the aorta above the coeliac trunk, superior mesenteric vein, splenic vein and portal vein (PV). In the volunteer cohort there was a marked increase in blood flow post-meal within the PV (p = 0.028), not seen in the patient cohort (p = 0.116). Similarly, there were significant flow changes within the SMA of volunteers (p = 0.028) but not for the patient group (p = 0.116). Our pilot data has shown that there is a significant haemodynamic response to meal challenge in the PV and SMA in normal subjects compared to clinically apparent CMI patients. Therefore, the interrogation of mesenteric venous vessels exclusively is a feasible method to measure post-prandial flow changes in CMI patients.

scholarly journals Four-Dimensional Flow MRI of Abdominal Veins: A Systematic Review

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 767
Author(s):  
Simon O. Haarbye ◽  
Michael B. Nielsen ◽  
Adam E. Hansen ◽  
Carsten A. Lauridsen
Keyword(s):  
Systematic Review ◽  
Blood Flow ◽  
Portal Hypertension ◽  
Healthy Subjects ◽  
Visual Quality ◽  
Sampling Strategies ◽  
4D Flow Mri ◽  
4D Flow ◽  
Dimensional Flow ◽  
Flow Mri

The aim of this systematic review is to provide an overview of the use of Four-Dimensional Magnetic Resonance Imaging of vector blood flow (4D Flow MRI) in the abdominal veins. This study was composed according to the PRISMA guidelines 2009. The literature search was conducted in MEDLINE, Cochrane Library, EMBASE, and Web of Science. Quality assessment of the included studies was performed using the QUADAS-2 tool. The initial search yielded 781 studies and 21 studies were included. All studies successfully applied 4D Flow MRI in abdominal veins. Four-Dimensional Flow MRI was capable of discerning between healthy subjects and patients with cirrhosis and/or portal hypertension. The visual quality and inter-observer agreement of 4D Flow MRI were rated as excellent and good to excellent, respectively, and the studies utilized several different MRI data sampling strategies. By applying spiral sampling with compressed sensing to 4D Flow MRI, the blood flow of several abdominal veins could be imaged simultaneously in 18–25 s, without a significant loss of visual quality. Four-Dimensional Flow MRI might be a useful alternative to Doppler sonography for the diagnosis of cirrhosis and portal hypertension. Further clinical studies need to establish consensus regarding MRI sampling strategies in patients and healthy subjects.

scholarly journals 4D flow MRI—Automatic assessment of blood flow in cerebral arteries

2018 ◽  
Vol 5 (1) ◽  
pp. 015003
Author(s):  
Tora Dunås ◽  
Anders Wåhlin ◽  
Laleh Zarrinkoob ◽  
Jan Malm ◽  
Anders Eklund
Keyword(s):  
Blood Flow ◽  
Cerebral Arteries ◽  
Automatic Assessment ◽  
4D Flow Mri ◽  
4D Flow ◽  
Flow Mri

scholarly journals 4D Flow with MRI

2020 ◽  
Vol 22 (1) ◽  
pp. 103-126 ◽  
Author(s):  
Gilles Soulat ◽  
Patrick McCarthy ◽  
Michael Markl
Keyword(s):  
3D Visualization ◽  
Three Dimensional ◽  
Circulatory System ◽  
Vascular Diseases ◽  
Cerebrovascular Diseases ◽  
Flow Imaging ◽  
4D Flow Mri ◽  
4D Flow ◽  
Flow Mri ◽  
Human Circulatory System

Magnetic resonance imaging (MRI) has become an important tool for the clinical evaluation of patients with cardiac and vascular diseases. Since its introduction in the late 1980s, quantitative flow imaging with MRI has become a routine part of standard-of-care cardiothoracic and vascular MRI for the assessment of pathological changes in blood flow in patients with cardiovascular disease. More recently, time-resolved flow imaging with velocity encoding along all three flow directions and three-dimensional (3D) anatomic coverage (4D flow MRI) has been developed and applied to enable comprehensive 3D visualization and quantification of hemodynamics throughout the human circulatory system. This article provides an overview of the use of 4D flow applications in different cardiac and vascular regions in the human circulatory system, with a focus on using 4D flow MRI in cardiothoracic and cerebrovascular diseases.

Usefulness of 4D-Flow MRI in Mapping Flow Distribution Through Failing Fontan Circulation Prior to Cardiac Intervention

2019 ◽  
Vol 40 (5) ◽  
pp. 1093-1096 ◽  
Author(s):  
Daniel McLennan ◽  
Michal Schäfer ◽  
Max B. Mitchell ◽  
Gareth J. Morgan ◽  
Dunbar Ivy ◽  
...  
Keyword(s):  
Flow Distribution ◽  
Fontan Circulation ◽  
4D Flow Mri ◽  
4D Flow ◽  
Cardiac Intervention ◽  
Flow Mri ◽  
Failing Fontan

scholarly journals 4D flow MRI of the aorta demonstrates age- and gender-related differences in aortic size and blood flow velocity in healthy subjects

2015 ◽  
Vol 17 (S1) ◽  
Author(s):  
Julio Garcia ◽  
Kelly B Jarvis ◽  
Susanne Schnell ◽  
SC Malaisrie ◽  
Colleen Clennon ◽  
...  
Keyword(s):  
Blood Flow ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Healthy Subjects ◽  
4D Flow Mri ◽  
4D Flow ◽  
Age And Gender ◽  
Flow Mri ◽  
And Gender ◽  
Aortic Size
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