Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are common
<br>conditions with a rising burden. Yet, there are significant management gaps between clinical
<br>guidelines and practice in patients with NAFLD and NASH. Further, there is no single global
<br>guiding strategy for the management of NAFLD and NASH. The American Gastroenterological
<br>Association, in collaboration with seven professional associations, convened an international
<br>conference comprising 32 experts in gastroenterology, hepatology, endocrinology, and primary
<br>care providers from the U.S., Europe, Asia, and Australia. Conference content was informed by
<br>the results of a national NASH Needs Assessment Survey. The participants reviewed and
<br>discussed published literature on global burden, screening, risk stratification, diagnosis, and
<br>management of individuals with NAFLD, including those with NASH. Participants identified
<br>promising approaches for clinical practice and prepared a comprehensive, unified strategy for
<br>primary care providers and relevant specialists encompassing the full spectrum of NAFLD/NASH
<br>care. They also identified specific high-yield targets for clinical research and called for a unified,
<br>international public health response to NAFLD and NASH.