The KLOE detector at the DA[Formula: see text]NE [Formula: see text]-factory has been operating in two periods from 2001–2006 and from 2014–2018 collecting a large sample of [Formula: see text]-meson decays. This allowed to perform precision measurements and studies of fundamental symmetries, and searches of New Physics phenomena. In this overview, the results of KLOE and KLOE-2 Collaborations are presented. The most recent results from the KLOE experiment are discussed, covering: the measurement of the running fine-structure constant [Formula: see text], the Dalitz plot measurement of [Formula: see text], the search of a [Formula: see text] boson, tests of discrete symmetries and quantum decoherence.