Next Generation Diagnostic Pathology Using Digital Pathology and Artificial Intelligence (AI) Tools to Augment a Pathological Diagnosis

Approximately 850,000 American women are diagnosed with the dreaded word cancer every year, while two-thirds of cancer deaths in the country are preventable. Although different types of cancer are worrisome, experts say that more than worrying, one should look for ways to control and prevent them, which are also readily available. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening; Treatment; Management

Diagnostic Pathology in the Era of Precision Medicine

The ever-increasing importance of targeted therapy in the management of cancerous and non-neoplastic diseases calls for novel, advanced techniques of diagnostic pathology. The past decade has witnessed substantial changes in how cancer patients are managed, with a pronounced focus on precision medicine based on genomic profiles and gene expression analysis, thus discarding the “one-size-fits-all” approach1.

On the Shoulders of a Giant: Contributions of Thomas Grogan, MD to Hematopathology

The story of Thomas Grogan, MD is one of the most compelling narratives in the modern history of pathology. Progressing from a quintessential academic pathologist to an entrepreneur and a renowned inventor, his remarkable journey is one of creativity, courage, and a keen focus on improving the care of cancer patients. By enabling precision health and empowering the pathologist in that mission, he transformed the landscape of diagnostic pathology. In this review, we describe some of his salient contributions and how his vision has shaped and continues to shape hematopathology today.

Down the rabbit hole: a quick guide for histopathology description

ABSTRACT: Histopathology is an old science that is still currently utilized for disease diagnosis and research. The routinely processed histologic slides stained with hematoxylin and eosin are still used worldwide in most if not every histopathology laboratory. The technique is inexpensive, quick to perform, and allows the diagnosis of a fantastic variety of tissue changes and diseases. Skills in description and interpretation in histopathology are a craft that can be learned by repeatedly and systematically observing simple rules. In this article, we offer a few advices to help trainees in veterinary pathology at the start of their careers. Those advices are drawn from our experience in the diagnostic pathology routine and from the veterinary pathology literature. To enhance the understanding of these important steps in the histopathologic description of tissues, we decided to illustrate most concepts expressed here. We hope that our effort can add a bit to the development of future pathologists. Just like Alice, let us follow the White Rabbit into his burrow for this challenging experience!