intended target
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2021 ◽  
Vol 118 (52) ◽  
pp. e2107019118
Author(s):  
Chen Yu ◽  
Yayun Zhang ◽  
Lauren K. Slone ◽  
Linda B. Smith

The learning of first object names is deemed a hard problem due to the uncertainty inherent in mapping a heard name to the intended referent in a cluttered and variable world. However, human infants readily solve this problem. Despite considerable theoretical discussion, relatively little is known about the uncertainty infants face in the real world. We used head-mounted eye tracking during parent–infant toy play and quantified the uncertainty by measuring the distribution of infant attention to the potential referents when a parent named both familiar and unfamiliar toy objects. The results show that infant gaze upon hearing an object name is often directed to a single referent which is equally likely to be a wrong competitor or the intended target. This bimodal gaze distribution clarifies and redefines the uncertainty problem and constrains possible solutions.


2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi229-vi229
Author(s):  
Kirsten van Baarsen ◽  
Peter Woerdeman ◽  
Mariam Slot ◽  
Eelco Hoving

Abstract BACKGROUND With the incorporation of the robotic alignment module Cirq (Brainlab, Germany) into our neurosurgical armamentarium, we aimed to know our baseline accuracy in stererotactic biopsies. We therefore retrospectively reviewed our data on biopsy accuracy for brain(stem) tumors using the non-robotic alignment instrument Varioguide (Brainlab, Germany). Because of unexpectedly large deviations from the intended target, we sought to improve our registration accuracy when we introduced Cirq. Intraoperative 3D CT with bone fiducials was added to the pre-operative 3D T1 MRI with skin fiducials. This made it possible to compare surgical devices as well as registration methods. AIMS To share our experience with the new robotic alignment module Cirq for navigated brain(stem) tumor biopsies and to evaluate its target accuracy with bone fiducial registration, as compared to the previously used Varioguide with skin fiducial registration. METHODS All patients (0–18 years old) that underwent a brain(stem) biopsy in our institution were included. Over 2018–2020, data were collected retrospectively (cohort Varioguide with 3D T1 MRI registration with skin fiducials). From 2021, data were collected prospectively (cohort Cirq with both 3D T1 MRI registration with skin fiducials and intraoperative CT registration with bone fiducials). For both cohorts, Euclidian distances were calculated between the intended target and the obtained target. For the prospective cohort, registration errors were calculated for bone versus skin fiducials. PRELIMINARY REUSLTS The deviation from the intended target was much smaller in the Cirq cohort versus the Varioguide cohort. Within the Cirq cohort, registration errors were submillimetric for bone fiducial registration as compared to several millimeters for skin fiducial registration. CONCLUSION: The Cirq robotic arm is convenient, safe and highly accurate, especially when combined with intraoperative 3D CT bone fiducial registration. Skin fiducial registration does not offer the level of precision that is mandatory in brainstem tumor biopsies.


Author(s):  
Alexander Dukalskis

How exactly do authoritarian states manage their image abroad, and what are the causal chains linking their activities to their desired outcomes of internal and external security? This chapter proposes four sets of mechanisms to explain how authoritarian image management is meant to have tangible effects for states that undertake such a strategy. The framework categorizes specific tactics (i.e., soft power initiatives or silencing exiles) into higher-order groupings of mechanisms. The idea is to create a framework that can facilitate case study and comparative causal analysis across a range of contexts. Four mechanisms are proposed that vary along two dimensions: their form (promotional vs. obstructive) and their intended target (diffuse vs. specific). The chapter provides the tools to trace the causal processes associated with authoritarian image management.


2021 ◽  
Vol 20 (01) ◽  
pp. C08
Author(s):  
Maria Elena Villar

From a strategic communication perspective, for any communication to be effective, it must be audience-centered, with content and delivery channels that are relevant to its intended target. When trying to reach culturally specific communities or other groups that are not otherwise connected with science research, it is crucial to partner with community members to co-create content through media that is appealing and culturally competent. This commentary considers some examples including storytelling through ‘fotonovelas’ and radio stories, community drama and serious games.


2021 ◽  
Vol 13 (1) ◽  
pp. 1-20
Author(s):  
William R. Simpson ◽  
Kevin E. Foltz

Network defense implies a comprehensive set of software tools to preclude malicious entities from conducting activities such as exfiltration of data, theft of credentials, blocking of services and other nefarious activities. For most enterprises at this time, that defense builds upon a clear concept of the fortress approach. Many of the requirements are based on inspection and reporting prior to delivery of the communication to the intended target. These inspections require decryption of packets and this implies that the defensive suite either impersonates the requestor, or has access to the private cryptographic keysof the servers that are the target of communication. This is in contrast to an end-to-end paradigm where known good entities can communicate directly and no other entity has access to the content unless that content is provided to them. There are many new processes that require end-to-end encrypted communication, including distributed computing, endpoint architectures, and zero trust architectures and enterprise level security. In an end-to-end paradigm, the keys used for authentication, confidentiality, and integrity reside only with the endpoints. This paper examines a formulation that allows unbroken communication, while meeting the inspection and reporting requirements of a network defense. This work is part of a broader security architecture termed Enterprise Level Security (ELS)framework.


2021 ◽  
Vol 6 ◽  
pp. 3
Author(s):  
Erin E. Cutts ◽  
Gillian C. Taylor ◽  
Mercedes Pardo ◽  
Lu Yu ◽  
Jimi C. Wills ◽  
...  

Condensin complexes compact and disentangle chromosomes in preparation for cell division. Commercially available antibodies raised against condensin subunits have been widely used to characterise their cellular interactome. Here we have assessed the specificity of a polyclonal antibody (Bethyl A302-276A) that is commonly used as a probe for NCAPH2, the kleisin subunit of condensin II, in mammalian cells. We find that, in addition to its intended target, this antibody cross-reacts with one or more components of the SWI/SNF family of chromatin remodelling complexes in an NCAPH2-independent manner. This cross-reactivity, with an abundant chromatin-associated factor, is likely to affect the interpretation of protein and chromatin immunoprecipitation experiments that make use of this antibody probe.


Author(s):  
Tripti Dhote

Leveraging a celebrity for instant recognition and visibility or building significant brand credibility and driving sales has been a long-established recipe for success over the years. Engaging a reputed face for brand promotion has ever been an exorbitant investment. Digital or social media as a communication platform has not only driven brands to create a desired recall without the burden of unreasonable spends, but has also strengthened and empowered celebrity engagement like never before by throwing a versatile array of options for individual branding and visibility. This chapter aims to explore and analyse the engagement of celebrity on different social media platforms like Facebook and Instagram, Twitter etc. with special reference to Bollywood. It delves into understanding the engagement patterns; aspects of celebrity evoked; brand impact; media celebrity brand fit, and intended target audience whether it leads to action or Influences perceptions.


2020 ◽  
Vol 3 (4) ◽  
Author(s):  
Adi Sutrisno ◽  

Google Translate is a free and practical online translation service that allows millions of people around the globe to translate words, phrases, sentences, and paragraphs into an intended target language. However, in 2015, some Google Translate users in Indonesia, filed complaints, asserting that the machine was often inaccurate, speculating that it could only translate languages at the micro-level of words and phrases, rather than complete sentences or paragraphs. This research works to examine the accuracy as well as the shortcomings of Google Translate, in the context of English to Indonesian translations, in order to critically engage the complaints made by Google users. For the purpose of this study, 80 English sentences were translated using Google Translate and assessed for accuracy using a table adapted from Memsource criteria. Both the original sentences and their translated versions were analyzed using a sentence pair matrix to determine the machine’s failings and areas for improvement. The results challenged those initial speculations which suggested Google Translate is only effective with words and phrases. On the contrary, Memsource proved to be a useful tool in demonstrating a reasonable level of accuracy, accurately translating 60.37% of Indonesian-English sentences and vice versa.


2020 ◽  
Author(s):  
Adi Sutrisno

Google Translate is a free and practical online translation service that allows millions of people around the globe to translate words, phrases, sentences, and paragraphs into an intended target language. However, in 2015, some Google Translate users in Indonesia, filed complaints, asserting that the machine was often inaccurate, speculating that it could only translate languages at the micro-level of words and phrases, rather than complete sentences or paragraphs. This research works to examine the accuracy as well as the shortcomings of Google Translate, in the context of English to Indonesian translations, in order to critically engage the complaints made by Google users. For the purpose of this study, 80 English sentences were translated using Google Translate and assessed for accuracy using a table adapted from Memsource criteria. Both the original sentences and their translated versions were analyzed using a sentence pair matrix to determine the machine’s failings and areas for improvement. The results challenged those initial speculations which suggested Google Translate is only effective with words and phrases. On the contrary, Memsource proved to be a useful tool in demonstrating a reasonable level of accuracy, accurately translating 60.37% of Indonesian-English sentences and vice versa.


2020 ◽  
Author(s):  
Adi Sutrisno

Google Translate is a free and practical online translation service that allows millions of people around the globe to translate words, phrases, sentences, and paragraphs into an intended target language. However, in 2015, some Google Translate users in Indonesia, filed complaints, asserting that the machine was often inaccurate, speculating that it could only translate languages at the micro-level of words and phrases, rather than complete sentences or paragraphs. This research works to examine the accuracy as well as the shortcomings of Google Translate, in the context of English to Indonesian translations, in order to critically engage the complaints made by Google users. For the purpose of this study, 80 English sentences were translated using Google Translate and assessed for accuracy using a table adapted from Memsource criteria. Both the original sentences and their translated versions were analyzed using a sentence pair matrix to determine the machine’s failings and areas for improvement. The results challenged those initial speculations which suggested Google Translate is only effective with words and phrases. On the contrary, Memsource proved to be a useful tool in demonstrating a reasonable level of accuracy, accurately translating 60.37% of Indonesian-English sentences and vice versa.


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