Amiri Baraka's "In Memory of Radio": Marxist Dialectics

The paper discusses the dialectics of Baraka's Marxism in relation to "In Memory of Radio," one of his best poems written during his Beat period and published in 1962. Though much of his poetry written during this period is judged by critics as having nothing to do with Marxism and thus no attempt is to be made to discuss his poetic production in the light of this literary theory, other literary critics prove that the seeds of establishing himself as a Marxist poet can find its roots in his Beat poetry prior to his transition to other two phases, namely the phase of Black nationalism and the phase of Marxist-Leninism.

A Clustering Analysis Method for Massive Music Data

Clustering analysis plays a very important role in the field of data mining, image segmentation and pattern recognition. The method of cluster analysis is introduced to analyze NetEYun music data. In addition, different types of music data are clustered to find the commonness among the same kind of music. A music data-oriented clustering analysis method is proposed: Firstly, the audio beat period is calculated by reading the audio file data, and the emotional features of the audio are extracted; Secondly, the audio beat period is calculated by Fourier transform. Finally, a clustering algorithm is designed to obtain the clustering results of music data.

New observations of DW Cnc: where is the 38 min signal?

ABSTRACT We present extensive radial velocity observations of the intermediate polar DW Cnc during its 2018–2019 low state. We show that the 86 min signal associated with the orbital period is strong in our radial velocity analysis, power spectrum search, and in our Doppler tomography. However, we find that the velocity modulation associated with the 70 min beat period and the 38 min spin cycle is dramatically weaker than that previously observed. We put forward two interpretations for this change. The first is that a sudden drop into a low state detected in 2018–2019 caused an episode of low mass transfer from the companion, thus inhibiting the lighthouse effect produced by the rebound emission. The second is that this is a consequence of a rare outburst detected in 2007 by Crawford et al. (2008). We find this post-outburst hypothesis to be less likely. If the first scenario is correct, we predict that DW Cnc will recover its intermediate polar characteristics. A new ephemeris is presented by combining Patterson et al. (2004) radial velocities with ours.

Modulated Pseudo-hermitian dimer

We investigate a modulated pseudo-Hermitian optical dimer. The parameter regions where the eigenmodes of the dimer retain their power are determined. It was shown that such a dimer has several exceptional points and it was found that the dimer modes can maintain their average power over the period, even if each of the segments is in the PT-broken phase. On the other hand, even if each segment is in the PT-symmetric phase, the average power of the dimer may not preserve. This feature is determined by the ratio between the length of the dimer and the beat period of the signal that occurs in individual segments of the dimer.

TESS observations of the asynchronous polar CD Ind: mapping the changing accretion geometry

ABSTRACT We present the results of near continuous TESS optical observations of the asynchronous polar CD Ind (RX J2115−5840). The 27.9 d long light curve, with 2 min resolution, reveals remarkable changes in the magnetic accretion geometry of the system over the 7.3 d beat period. We have modelled the changes in the optical spin period pulse shape using a cyclotron emission mapping technique. The resulting cyclotron emission maps of the magnetic white dwarf reveal how the accretion geometry changes from single- to two-pole accretion and back over the beat cycle. Finally, we present the results from particle-based numerical magnetic accretion simulations, which agree with our interpretation of the changing accretion scenario.

Abstract 95: Pharmacological Characterization of Adenosine Effects on Spontaneously Beating Human-IPSC-Derived Cardiomyocytes

Purified human-Induced Pluripotent Stem Cell-derived cardiomyocytes (hIPSC-CMs: iCells®, Cellular Dynamics) form electrically coupled, spontaneously beating cell monolayers (syncytia) upon plating and continuous culture. In this study, we investigate the pharmacology of the hIPSC-CM adenosine (ADO) response via the use of selective A1 and A2A-receptor antagonists and equilibrative nucleoside transporter type-1 (ENT1) inhibitors. After a 14-day culture in 96-well impedance electrode-plates (ACEA Biosciences), the spontaneous iCell beating rates are highly stable from well to well, with a mean beat period of 1.7 sec at 37°C, and a coefficient of variation (CV) < 1% . Extracellularly applied ADO inhibits the spontaneous beating rate of iCells with an IC 50 = 2.2 μM, and a saturation value of near 50% inhibition. ADO also destabilizes the beat period (CV EC 50 = 1.2 μM) with a maximum CV of 20% at saturating ADO concentrations. The ADO IC 50 is shifted to 248 μM upon pre-incubation of the iCells with 1 μM of an A1-selective antagonist DPCPX (A1 K i =3.9 nM), but not the A2A-selective antagonist ZM241385 (A2A K i =1nM). The duration of the depressive effect of ADO on beating rate is transient, even at super-saturating ADO concentrations, and depends on the well ADO concentration. The ENT1 inhibitor Draflazine (ENT1 pK i =9.5) pre-applied at 0.1 μM increases ADO sensitivity by 4-fold one hour after ADO application. Moreover, at any given ADO concentration, the duration of beating rate depression can be prolonged in a concentration-dependent manner by ENT1 inhibitors, with the prolongation-response curve nearly matching the ENT1 IC 50 s for tested ENT1 inhibitors (Draflazine, NBTI, Dilazep, and Dipyridamole). These findings suggest that the pool of ADO in the test well is cleared by uptake via endogenous ENT1 and support the role of equilibrative ADO uptake in limiting the duration of action of ADO on A1 receptors in cardiomyocytes. We are extending our investigation to the downstream target of A1 receptor activity, and the putative role of IK ACH/ADO as the underlying mechanism of beat rate slowing and irregularity. In conclusion, the hIPSC-CM model provides a useful model for investigation of ADO pharmacology of the heart.