Assessment of cardiac morphology, function, and pathology requires the use of different pulse sequences (spin echo, gradient echo, hybrid echo), preparation pulses to manipulate image contrast, and data acquisition strategies such as parallel imaging, single-shot versus segmented acquisition, or contrast versus non-contrast imaging techniques. This chapter presents some of the main cardiac applications: morphology and function, stress perfusion imaging, viability assessment using late gadolinium enhancement, flow quantification, angiography, and fat suppression techniques. For each application, a description of its use within the clinical context is provided, along with the main sequence parameters and their effect on image contrast, acquisition time, and image quality.