Some experimental data on the etiology of uterine fibroids

Taking into account the great interest in identifying the role of the nervous system in the processes of tumor growth and the insufficient study of morphological changes in the nervous apparatus of neoplasms, in our clinic (Head - Prof. AM Foy), since 1955, work has been carried out to study the effect of prolonged hyperestrogenism on the nervous apparatus of the uterus during the development of experimental fibroids in it. Experiments with long-term administration of estrogenic hormones were carried out on 120 non-castrated female guinea pigs weighing from 150.0 to 250.0, which were divided into 4 groups.

To the morphology of the terminal nervous apparatus in the muscles of voluntary movement

According to the views prevailing at the present time, the muscles of voluntary movement do not have independent sensitive devices, and all the manifestations of muscle sensitivity, whether this latter is expressed in the form of pain sensitivity, or in the form of muscular feeling, are explained by the presence of tendon sensory nerve endings, internum , - in a word, in connective tissue and connective tissue formations, exposed to mechanical impact from the contracting muscles.

Structural changes in skeletal muscles in hypokinesia and physical loading in the posthypokinetic period of recovery of rats’ organisms

This article reports the study of histo-ultrastructural changes of different structural components of the direct muscle of the thigh of sexually mature male rats over a prolonged period of hypokinesia and subsequent application of physical loading of average aerobic power. Using a light optical, electron microscope (for the exposure of structural transformations of muscle components) and histochemical (for determination of activity of succinate dehydrogenase according to the Nahlas method to identify muscle fibers with different phenotypes) methods, we studied the structural manifestations of adaptation of muscle fibres under prolonged (240 day) hypokinesia and 15–30 episodes of physical loading of average aerobic power in the posthypokinetic period among 55 sexually mature rats. Under prolonged hypokinesis we primarily observed changes in the intramuscular network and morphometric changes in the blood vessels. These data closely correlate with the progression of changes of the subcellular components responsible for energetic and flexible balance of muscle fibres. We found that fast oxygen-glycolytic muscle fibers and their peripheral nervous apparatus are the most sensitive to prolonged hypokinesia. As a result of application of physical loading of average aerobic power, reparative regeneration is intensified, which substantially shortens the period of recovery of structural-functional properties of skeletal muscles in the conditions of hypokinetic disorders. Thus, in prolonged hypokinesia, changes primarily affect the sources of blood supply to skeletal muscles, with the secondary development of reverse processes in muscle fibers and peripheral nervous apparatus with certain morphometric signs.

Age-related changes in the nervous apparatus of the blood vessels in the spinal cord

This paper was designed to study changes in the nervous apparatus of the blood vessels in the spinal cord with a view to determining the biological age of man. The pial and intramedullary vascular systems of the brain and spinal cord were examined in different periods of postnatal ontogenesis (between the age of 1 to 90 years). The data obtained on the age-related rearrangement of the nervous apparatus of the spinocerebral arterial vessels can also be used for the solution of practical problems encountered in the practical work of forensic medical experts.

Laser therapy for tubal infertility

In the literature we found reports on anti-inflammatory, analgesic, resolving effect of low-energy laser light in the red part of the spectrum, its irritating effect on receptors of the nervous apparatus, ability to induce ovulation. We have not found any works on laser beams application in treatment of tubal infertility, but taking into account the above mentioned we can assume the possibility of restoration of female reproductive function by laser treatment.